COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,386 Articles (22,816 medRxiv, 8,570 bioRxiv)

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Effects of Mutations in the Receptor-Binding Domain of SARS-CoV-2 Spike on its Binding Affinity to ACE2 and Neutralizing Antibodies Revealed by Computational Analysis
Bozdaganyan, M. E., Sokolova, O. S., Shaitan, K. V., Kirpichnikov, M. P., Orekhov, P. S.
10.1101/2021.03.14.435322 — Posted: 2021-03-15
One-shot identification of SARS-CoV-2 S RBD escape mutants using yeast screening
Francino Urdaniz, I., Steiner, P. J., Kirby, M., Zhao, F., Haas, C. M., Barman, S., Rhodes, E. R., Peng, L., Sprenger, K., Jardine, J., Whitehead, T. A.
10.1101/2021.03.15.435309 — Posted: 2021-03-15
S-acylation controls SARS-Cov-2 membrane lipid organization and enhances infectivity
Mesquita, F. S., Abrami, L., Sergeeva, O., Turelli, P., Kunz, B., Raclot, C., Paz Montoya, J., Abriata, L., Dal Peraro, M., Trono, D., D'Angelo, G., van der Goot, F. G.
10.1101/2021.03.14.435299 — Posted: 2021-03-15
Structure, Mechanism and Crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase
Newman, J. A., Douangamath, A., Yazdani, S., Yosaatmadja, Y., Aimon, A., Brandao-Neto, J., Dunnett, L., Gorrie-Stone, T., Skyner, R., Fearon, D., Schapira, M., von Delft, F., Gileadi, O.
10.1101/2021.03.15.435326 — Posted: 2021-03-15
Differential gene expression by RNA-Seq in Sigma-2 Receptor/TMEM97 knockout cells reveals its role in complement activation and SARS-CoV-2 viral uptake
Riad, A., Aubert, Y., Zeng, C., Graham, T. J. A., Petersson, E. J., Capell, B. C., Mach, R. H.
10.1101/2021.03.14.435180 — Posted: 2021-03-15
A map of direct SARS-CoV-2 protein interactions implicates specific human host processes
Kim, D.-K., Weller, B., Lin, C.-W., Sheykhkarimli, D., Knapp, J. J., Kishore, N., Sauer, M., Rayhan, A., Young, V., Marin-de la Rosa, N., Pogoutse, O., Spirohn, K., Strobel, A., Laval, F., Schwehn, P., Li, R., Simin, R., Altmann, M., Cassonnet, P., Dugied, G., Cote, A. G., Elorduy Vergara, L., Hazelwood, I., Liu, B. B., Nguyen, M., Pandiarajan, R., Rodriguez Coloma, P. A., Willems, L., Twizere, J.-C., Demeret, C., Jacob, Y., Hao, T., Hill, D. E., Falter, C., Vidal, M., Calderwood, M. A., Roth, F. P., Falter-Braun, P.
10.1101/2021.03.15.433877 — Posted: 2021-03-15
A novel soluble ACE2 protein totally protects from lethal disease caused by SARS-CoV-2 infection
Hassler, L., Wysocki, J., Gelarden, I., Tomatsidou, A., Nicoleascu, V., Randall, G., Henkin, J., Yeldandi, A., Batlle, D.
10.1101/2021.03.12.435191 — Posted: 2021-03-15
Durability of SARS-CoV-2-specific IgG responses in saliva for up to 8 months after infection
Randad, P. R., Pisanic, N., Kruczynski, K., Howard, T., Gregory Rivera, M., Spicer, K., Antar, A. A. R., Penson, T., Thomas, D. L., Pekosz, A., Ndahiro, N., Aliyu, L., Betenbaugh, M. J., Manley, H., Detrick, B., Katz, M., Cosgrove, S., Rock, C., Zyskind, I., Silverberg, J. I., Rosenberg, A. Z., Duggal, P., Manabe, Y. C., Collins, M. H., Heaney, C. D.
10.1101/2021.03.12.21252149 — Posted: 2021-03-15
HIV service interruptions during the COVID-19 pandemic in China: the role of HIV service challenges and institutional response from healthcare professional's perspective
Yang, X., Zeng, C., Tam, C. C., Qiao, S., Li, X., Shen, Z., Zhou, Y.
10.1101/2021.03.12.21253463 — Posted: 2021-03-15
Novel highly divergent SARS-CoV-2 lineage with the Spike substitutions L249S and E484K
Laiton-Donato, K., Usme-Ciro, J. A., Franco-Munoz, C., Alvarez-Diaz, D. A., Ruiz-Moreno, H. A., Reales-Gonzalez, J., Prada, D. A., Corchuelo, S., Herrera-Sepulveda, M. T., Naizaque, J., Santamaria, G., Wiesner, M., Walteros, D. M., Ospina Martinez, M. L., Marcela Mercado-Reyes, M.
10.1101/2021.03.12.21253000 — Posted: 2021-03-15 Discussion: Onsite

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).