COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,082 Articles (22,658 medRxiv, 8,424 bioRxiv)

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Glycans modulate the adsorption of RBD Glycoproteins on polarizable surfaces
Bosch, A., Menacho, W., Perez, R., V. Guzman, H. V.
10.1101/2025.09.30.679433 — Posted: 2025-10-01
Enhanced human antigen-specific B cell responses using in vitro 3D tonsil cultures containing stromal cells
Braham, M. V. J., de Gast, M., Babii, L., Kruijer, S., Bestebroer, T. M., Richard, M., Claireaux, M., van Ham, M. S., de Wit, J., van Els, C. A. C. M., ten Brinke, A., van Gils, M.
10.1101/2025.09.30.679470 — Posted: 2025-10-01
Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase
Georgiou, I., Robinson, C., O'Byrne, S., Matsuda, A., Grygier, P., Smith, C., O'Neill, S., Ahmad, S. A., Post, J. M., Groenewold, M. G., Urakova, N., Wanningen, P., Kresik, L., Plewka, J., Delpal, A., See, K., Eadsforth, T., Norval, S., Wierzbicka, K., Decroly, E., Saikatendu, K. S., Chang, E., Snijder, E. J., Pyrc, K., Czarna, A., Scott, D. E., Gilbert, I. H.
10.1101/2025.09.30.679521 — Posted: 2025-10-01
Rational Design of Multiclade Coronavirus Spike Immunodominant Domain Nanoparticles Elicit Broad Antibody Responses
Dzuvor, C. K. O., Moak, S., McManus, L. R., Thomas, A., Dzordzorme, A. E., Kim, T., Joseph, J., Foley, V., Gordon, I. J., Novik, L., Holman, L. A., Dropulic, L. K., McNamara, R. P., Corbett-Helaire, K. S.
10.1101/2025.10.01.679649 — Posted: 2025-10-01
Plasma nirmatrelvir and molnupiravir concentrations required for inhibition of SARS CoV-2 replication differ between rhesus macaques and humans
Avila-Ponce de Leon, U., Esmaeili, S., Owens, K., Schiffer, J. T.
10.1101/2025.09.25.678525 — Posted: 2025-10-01
Approaches for estimating COVID-19 vaccine effectiveness using observational data in administrative databases: a systematic review
Chow, J. Y., Goh, Z. J., Li, R., Lim, D. Y., Wee, L. E., Lye, D. C. B., Tan, K. B., Lim, J. T.
10.1101/2025.09.29.25336864 — Posted: 2025-09-30
Longterm Impact of COVID-19 in Hospitalized and Ambulatory Jamaican Children
Mosha Miller, S. A.-P., Hicar, M. D., Berry, C.-L. S., Anderson, K. B., Lindo, J. F., Morse, G. D., Christie, C. D. C.
10.1101/2025.09.29.25335807 — Posted: 2025-09-30
Intensive care unit (ICU) healthcare workers' experiences during the COVID-19 pandemic in Chile: A qualitative interview study.
Castro-Avila, A. C., Aguilera, J.
10.1101/2025.09.28.25336848 — Posted: 2025-09-30
Entry, replication and innate immunity evasion of BANAL-236, a SARS-CoV-2-related bat virus, in Rhinolophus and human cells
Gracias, S., Donaire-Carpio, S., Vuillier, F., Le Seach, E., Vendramini, L., Moundib, A., Rutkowska, M., Cupic, A., Juste, J., Temmam, S., Donati, F., Martinez-Romero, C., Morel, N., SCHWARTZ, O., Krogan, N., Miorin, L., Demeret, C., Roingeard, P., Munier, S., Batra, J., Garcia-Sastre, A., Caval, v., Jouvenet, N.
10.1101/2025.09.29.679146 — Posted: 2025-09-29
Pre-Omicron Immunity Generates IgG⁺ but Not IgA⁺ Memory B Cells Reactive to Omicron Spike Protein
Tsoleridis, T., Singh, I., Onion, D., Chappell, J. G., Kelly, A., Nightingale, J., Valdes, A. M., Ollivere, B. J., Hoehn, K. B., Urbanowicz, R. A., Ball, J. K.
10.1101/2025.09.26.678818 — Posted: 2025-09-29

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).