COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,382 Articles (22,816 medRxiv, 8,566 bioRxiv)

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Pharmacokinetic-Pharmacodynamic Trade-offs in SARS-CoV-2 Main Protease Inhibitors Unveiled through Machine Learning and Molecular Dynamics Simulations
Souza, A. S. d., Amorim, V. M. d. F., Soares, E. P., de Souza, R. F., Guzzo, C. R.
10.1101/2025.05.14.654028 — Posted: 2025-05-15
Risk of new diagnoses and exacerbations of chronic conditions after SARS-CoV-2 infection: a systematic review update
Gaudet, L. A., Pillay, J., Zakaria, D., Saba, S., Tan, M., Vandermeer, B., Hartling, L.
10.1101/2025.05.13.25326692 — Posted: 2025-05-14
IL-4 and TGF-β Regulate Inflammatory cytokines and Cellular Infiltration in the Lung in Mouse-adapted SARS-CoV-2 Infection
Sima, S. T., Puebla-Clark, L., Gonzalez-Orozco, M., Endrino, M. J., Shelite, T. R., Tseng, H.-c., Martinez-Martinez, Y. B., Huante, M. B., Federman, H. G., Gbedande, K., Menachery, V. D., Siracusa, M. C., Dann, S. M., Endsley, J. J., Rajsbaum, R., Stephens, R.
10.1101/2025.05.13.653138 — Posted: 2025-05-14
Uridine cytidine kinases dictate the therapeutic response of molnupiravir via its bioactivation
Shu, H., Sharma, S., Alam, S., Frank, L., Tampere, M., van Kuilenburg, A. B. P., Valerie, N. C. K., Altun, M., Chabes, A., Rudd, S. G., Zhang, S. M.
10.1101/2025.05.13.653844 — Posted: 2025-05-14
Pre-pandemic mental health and brain characteristics predict adolescent stress and emotions during the COVID-19 pandemic
Risner, M., Hu, L., Stamoulis, C.
10.1101/2025.05.12.25327434 — Posted: 2025-05-13
Self-health Management and Role of Nurses of Diabetic Patients: A systematic review during COVID-19 Pandemic
Bo, Y.
10.1101/2025.05.12.25327369 — Posted: 2025-05-13
Self-Collected Finger-Prick Blood for Gene Expression Profiling: Unveiling Early Immune Responses in Mild COVID-19
Thiebaut, R., Lhomme, E., Hocini, H., Pellegrin, I., Boizard-Moracchini, A., Duvignaud, A., Perpere, M., Huchon, M., Lacabaratz, C., Surenaud, M., Anglaret, X., Malvy, D., Hejblum, B., COVERAGE study group, , Levy, Y.
10.1101/2025.05.06.25327063 — Posted: 2025-05-13
A luminescent attenuated SARS-CoV-2 for the identification and validation of drug-resistant mutants
Ma, Y., Ye, C., Khalil, A. M., Mahmoud, S. H., Sobolik, E. B., Greninger, A. L., Castro, E., Jackson, N., Bayoumi, M., Plemper, R. K., Martinez-Sobrido, L.
10.1101/2025.05.09.653029 — Posted: 2025-05-13
Phylogeny-driven design of broadly protective sarbecovirus receptor-binding domain nanoparticle vaccines
Addetia, A., Schaefer, A., Sprouse, K., Valdez, A., Taylor, A., Navarro, M.-J., Brown, J. T., Leaf, E., Miranda, M., Walls, A. C., Lee, J., Catanzaro, N. J., Treichel, C., Willoughby, I., Powers, J., Martinez, D. R., Vesari, B., Ravichandran, R., Seo, A. J., Stewart, C., Merz, B., Beirne, E., Zepeda, S., Cook, A., Pessaint, L., Sharma, A., Edwards, D., Lee, K., Smith, K., Starr, T. N., Baric, R., King, N. P., Veesler, D.
10.1101/2025.05.11.652904 — Posted: 2025-05-13
Generative model of SARS-CoV-2 variants under functional and immune pressure unveils viral escape potential and antibody resilience
Huot, M., Rosenbaum, P., Planchais, C., Mouquet, H., Monasson, R., Cocco, S.
10.1101/2025.05.12.653592 — Posted: 2025-05-13

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).