COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,822 Articles (22,968 medRxiv, 8,854 bioRxiv)

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Preferential boosting of SARS-CoV-2 Omicron lineage-specific immune responses by monovalent XBB.1.5 vaccination
Geers, D., Aguilar-Bretones, M., Zaeck, L. M., Gill, P. A., Gonzalez-Lopez, C., Handrejk, K., Tan, N. H., den Hartog, Y., Gommers, L., Bogers, S., Mykytyn, A. Z., Sablerolles, R. S. G., Goorhuis, A., Postma, D. F., Visser, L. G., Dalm, V. A. S. H., Lafeber, M., Kootstra, N. A., van Baarle, D., Haagmans, B. L., Koopmans, M. P. G., GeurtsvanKessel, C. H., van der Kuy, P. H. M., van Nierop, G. P., van Zelm, M. C., de Vries, R. D.
10.1101/2025.10.30.25339006 — Posted: 2025-11-02
Psycho-social and behavioral trends in Type 2 Diabetes self-management amongst medically underserved patients during the COVID-19 pandemic in an mHealth intervention
Campbell, E., Jia, H., Cassells, A., Lin, T., Cortez Lainez, J., Tobin, J. N., Smaldone, A., Desai, P., Hripcsak, G., Mamykina, L.
10.1101/2025.10.28.25338894 — Posted: 2025-11-02
Refined fully automated RT-qPCR assay for simultaneous detection of SARS-CoV-2, Influenza A/B, and RSV with target optimization for improved variant resilience
Pfefferle, S., Giersch, K., Noerz, D. S., Grunwald, M., Tang, H. T., Pflueger, L. S., Luetgehetmann, M.
10.1101/2025.10.29.25339068 — Posted: 2025-10-31
Fine-tuned Protein Language Model Identifies Antigen-specific B Cell Receptors from Immune Repertoires
Paco, K., Mendivil, M. P., Zhang, Z., Zebardast, S., Davila, C., Mooney, R. M., Olatoyinbo, P., Yang, T., Bassi, S., Gonzales, V., Chen, E., Ashraf, F. B., Roman, I. C., Felix, J. R., Alam, R. M., Lay, J. A., Johal, M. S., Le Roch, K. G., Tolstorukov, I., Hernandez, J. B., da Silva, F. L. B., Lonardi, S., Sazinsky, M. H., Ray, A.
10.1101/2025.10.30.685465 — Posted: 2025-10-31
Mechanism of substrate binding by the SARS-CoV-2 NiRAN domain and modulation of its activities during replication
Uday, A., Navas, M., Sivaprasad, P. S., Bhat, U., Saikrishnan, K.
10.1101/2025.10.31.685727 — Posted: 2025-10-31
Multimodal single-cell analysis following SARS-CoV-2 breakthrough infection reveals distinct B cell populations
Graus, L. T. M., Guerra, D., Chrysostomou, A., Kerster, G., van der Straten, K., van Rijswijk, J., Tejjani, K., Beaumont, T., Bree, G. J., Sanders, R. W., van Gils, M. J., Claireaux, M.
10.1101/2025.10.30.685644 — Posted: 2025-10-31
Efficacy and Safety of Vitamin D for COVID-19: A Living Evidence Synthesis Baseline report
Sabalete, T., Blasco, J. A., Rodriguez, R., Rosario, M. P., Rojas Reyes, M. X.
10.1101/2025.10.24.25338314 — Posted: 2025-10-30
Genetic Diversity Drives the Rate and Fitness Jumps of Detectable SARS-CoV-2 Recombination
Smith, K., Gangwar, P., Wertheim, J. O., Turakhia, Y.
10.1101/2025.10.28.25338993 — Posted: 2025-10-30
Persistent Spike antigenemia is not associated with Post-COVID condition
Coppens, L., Gorska, A., Hotterbeekx, A., Canziani, L. M., Mateescu, V. O., Gentilotti, E., Pirici, D., Berkell, M., Orchestra Biomarker Study Group, , Malhotra, S., Tacconelli, E., Kumar-Singh, S.
10.1101/2025.10.24.25338528 — Posted: 2025-10-30
Human Coronavirus HKU1 Neutralizing Monoclonal Antibodies Target Diverse Epitopes Within and Around the TMPRSS2 Receptor Binding Site
Wang, L., Joseph, J., Vasquez, S., Wrapp, D., Sheahan, T. P., Dzuvor, C. K. O., Rosen, O., Kirchdoerfer, R., Abiona, O. M., Hammond, C., Shi, W., Moak, S. P., Kong, W.-P., Zhang, Y., Eso, M. R., Brown, A. J., Ward, A., Baric, R. S., McLellan, J. S., Pierson, T. C., Mascola, J., Graham, B. S., Yassine, H., Barnes, C. O., Corbett-Helaire, K. S.
10.1101/2025.10.29.685445 — Posted: 2025-10-30

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