COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,886 Articles (22,568 medRxiv, 8,318 bioRxiv)

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The furin cleavage site is required for pathogenesis, but not transmission of SARS-CoV-2
Morgan, A. L., Vu, M. N., Zhou, Y., Lokugamage, K. G., Meyers, W., Alvarado, R. E., Ahearn, Y. P., Estes, L. K., Plante, J. A., Johnson, B. A., Suthar, M., Walker, D. H., Plante, K. S., Menachery, V. D.
10.1101/2025.03.10.642264 — Posted: 2025-03-11
Unveiling the Immune Landscape of COVID-19 and prolonged Long-COVID through Single-Cell RNA Sequencing
Springe, M. L., Vaivode, K., Saksis, R., Vainselbauma, N. M., Ansone, L., Briviba, M., Niedra, H., Rovite, V.
10.1101/2025.03.05.641671 — Posted: 2025-03-11
The protease inhibitor Nirmatrelvir synergizes with inhibitors of GRP78 to suppress SARS-CoV-2 replication
Al Krad, D., Stegmann, K. M., Dickmanns, A., Blaurock, C., Mohl, B.-P., Wille, S. J., Breithaupt, A., Britzke, T., Balkema-Buschmann, A., Dobbelstein, M.
10.1101/2025.03.09.642200 — Posted: 2025-03-11
Convergent and clonotype-enriched mutations in the light chain drive affinity maturation of a public antibody
Rao, V. N., Sapse, I. A., Cohn, H., Yoo, D.-K., Tong, P., Clark, J., Bozarth, B., Chen, Y., Srivastava, K., Singh, G., Krammer, F., Simon, V., Wesemann, D. R., Bajic, G., Coelho, C. H.
10.1101/2025.03.07.642041 — Posted: 2025-03-11
Investigating endothelial cell transduction and hexon:PF4 binding of ChAdOx1 in the context of VITT
Lovatt, C., Frangsmyr, L., Swift, E. A., Mundy, R. M., Parker, A. L.
10.1101/2025.03.09.642192 — Posted: 2025-03-11
From Plasmid to Pure Protein: Production and Characterization of SARS-CoV-2 PLpro
De Falco, A., Greene-Cramer, R., Shurina, B. A., Zakian, S., Acton, T. B., Ramelot, T. A., Montelione, G. T.
10.1101/2025.03.09.642282 — Posted: 2025-03-11
SARS-CoV-2 Exploits Host Translation and Immune Evasion Pathways via Viral RNA-Host Protein Interactions
Amahong, K., Liu, Y., Zhang, Z., Tao, L., Sarshad, A., Zhu, F.
10.1101/2025.03.07.642080 — Posted: 2025-03-10
Learning the language of protein-protein interactions
Ullanat, V., Jing, B., Sledzieski, S., Berger, B.
10.1101/2025.03.09.642188 — Posted: 2025-03-10
SARS-CoV-2 Infects Peripheral Sensory Neurons and Promotes Axonal Degeneration via TRPV1 Activation
Hong, Y., Co, V. A., Liu, S. T., Chun-Yee, R., Mok, B. W. Y., Chen, H.
10.1101/2025.03.06.641885 — Posted: 2025-03-10
City-wide Built Environment SARS-CoV-2 Detection for COVID-19 Surveillance
MacFadden, D. R., Fralick, M., Nott, C., Moggridge, J. A., Hicks, A. M., Van Bakel, T., Doukhanine, E., Hinz, A., Thampi, N., Bastien, P., Mansour, S., Khov, E., Burhunduli, T., Manuel, D. G., Wong, A., Kassen, R.
10.1101/2025.03.06.25323509 — Posted: 2025-03-07

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).