Channel:  Harvard Program in Therapeutic Sciences

126 Articles

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Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes
Doherty, L. M., Mills, C. E., Boswell, S. A., Liu, X., Hoyt, C. T., Gyori, B. M., Buhrlage, S. J., Sorger, P. K.
10.1101/2021.08.06.455458 — Posted: 2021-08-09
Single-sequence protein structure prediction using language models from deep learning
Chowdhury, R., Bouatta, N., Biswas, S., Rochereau, C., Church, G. M., Sorger, P. K., AlQuraishi, M. N.
10.1101/2021.08.02.454840 — Posted: 2021-08-04
A community-based approach to image analysis of cells, tissues and tumors
CSBC/PS-ON Image Analysis Working Group, , Vizcarra, J. C., Burlingame, E. A., Hug, C. B., Goltsev, Y., White, B. S., Tyson, D. R., Sokolov, A.
10.1101/2021.07.22.451363 — Posted: 2021-07-25
The gut bacterial natural product colibactin triggers induction of latent viruses in diverse bacteria
Silpe, J. E., Wong, J. W. H., Owen, S. V., Baym, M., Balskus, E. P.
10.1101/2021.05.24.445430 — Posted: 2021-05-25
Temporal and spatial topography of cell proliferation in cancer
Gaglia, G., Kabraji, S., Argyropoulou, D., Dai, Y., Wang, S., Bergholz, J., Coy, S., Lin, J.-R., Jeselsohn, R., Metzger, O., Winer, E. P., Dillon, D. A., Zhao, J. J., Sorger, P. K., Santagata, S.
10.1101/2021.05.16.443704 — Posted: 2021-05-17
Cancer patient survival can be accurately parameterized, revealing time-dependent therapeutic effects and doubling the precision of small trials
Plana, D., Fell, G., Alexander, B. M., Palmer, A. C., Sorger, P. K.
10.1101/2021.05.14.442837 — Posted: 2021-05-17
Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2
Patino-Galindo, J. A., Filip, I., Chowdhury, R., Maranas, C. D., Sorger, P. K., AlQuraishi, M., Rabadan, R.
10.1101/2020.02.10.942748 — Posted: 2021-04-06
Decreased thermal tolerance as a trade-off of antibiotic resistance
Herren, C. M., Baym, M.
10.1101/2021.04.05.438396 — Posted: 2021-04-05
Micro-region transcriptomics of fixed human tissue using Pick-Seq
Maliga, Z., Nirmal, A. J., Ericson, N. G., Boswell, S. A., U'Ren, L., Podyminogin, R., Chow, J., Chen, Y.-A., Chen, A. A., Weinstock, D. M., Lian, C. G., Murphy, G. F., Kaldjian, E. P., Santagata, S., Sorger, P. K.
10.1101/2021.03.18.431004 — Posted: 2021-03-19
MCMICRO: A scalable, modular image-processing pipeline for multiplexed tissue imaging
Schapiro, D., Sokolov, A., Yapp, C., Muhlich, J. L., Hess, J., Lin, J.-R., Chen, Y.-A., Nariya, M. K., Baker, G. J., Ruokonen, J., Maliga, Z., Jacobson, C. A., Farhi, S. L., Abbondanza, D., McKinley, E. T., Betts, C., Regev, A., Coffey, R. J., Coussens, L. M., Santagata, S., Sorger, P. K.
10.1101/2021.03.15.435473 — Posted: 2021-03-16

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