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130 Reviews — eLife — Bioinformatics

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Taxonium: a web-based tool for exploring large phylogenetic trees
Sanderson, T.
10.1101/2022.06.03.494608 — Posted: 2022-06-03 — Discussion: 2022-10-20  eLife
Comprehensive phylogenetic analysis of the ribonucleotide reductase family reveals an ancestral clade and the role of insertions and extensions in diversification
Burnim, A. A., Spence, M. A., Xu, D., Jackson, C., Ando, N.
10.1101/2022.04.23.489257 — Posted: 2022-04-23 — Discussion: 2022-08-11  eLife
Evaluation of in silico predictors on short nucleotide variants in HBA1, HBA2 and HBB associated with haemoglobinopathies
Tamana, S., Xenophontos, M., Minaidou, A., Stephanou, C., Harteveld, C. L., Bento, C., Traeger-Synodinos, J., Fylaktou, I., Yasin, N. M., Hamid, F. S. A., Esa, E., Halim-Fikri, H., Zilfalil, B. A., Kakouri, A. C., ClinGen Hemoglobinopathy VCEP, , Kleanthous, M., Kountouris, P.
10.1101/2022.04.07.484934 — Posted: 2022-04-09 — Discussion: 2022-08-02  eLife
Comprehensive machine-learning survival framework develop a consensus model in large scale multi-center cohorts for pancreatic cancer
Wang, L., Liu, Z., Liang, R., Wang, W., Zhu, R., Li, J., Xing, Z., Weng, S., Han, X., Sun, Y.-l.
10.1101/2022.05.15.492020 — Posted: 2022-05-16 — Discussion: 2022-07-18  eLife
Nomograms of Human Hippocampal Volume Shifted by Polygenic Scores
Janahi, M., Aksman, L. M., Schott, J., Altmann, A.
10.1101/2022.02.17.480931 — Posted: 2022-02-19 — Discussion: 2022-06-30  eLife
Systematic lncRNA mapping to genome-wide co-essential pathways uncovers cancer dependency on uncharacterized lncRNAs
Mitra, R., Adams, C. M., Eischen, C. M.
10.1101/2022.02.03.478941 — Posted: 2022-02-04 — Discussion: 2022-05-12  eLife
Benchmarking supervised signature-scoring methods for single-cell RNA sequencing data in cancer
Zheng, S., Nighat, N., Ye, Z., Chen, Y., Wang, X.
10.1101/2021.06.29.450404 — Posted: 2021-07-01 — Discussion: 2022-02-18  eLife
Rapid, Reference-Free Human Genotype Imputation with Denoising Autoencoders
Dias, R., Evans, D., Chen, S.-F., Chen, K.-Y., Chan, L., Torkamani, A.
10.1101/2021.12.01.470739 — Posted: 2021-12-02 — Discussion: 2022-02-16  eLife
Genetic, metabolic, and molecular insights into the diverse outcomes of diet-induced obesity in mice
Bachmann, A. M., Morel, J.-D. H., El Alam, G., Rodriguez-Lopez, S., de lima, T. I., Goeminne, L. J. E., Benegiamo, G., Bou Sleiman, M. S., Auwerx, J.
10.1101/2021.09.02.458729 — Posted: 2021-09-05 — Discussion: 2022-02-13  eLife
Discovering fragment length signatures of circulating tumor DNA using Non-negative Matrix Factorization
Renaud, G., Noergaard, M., Lindberg, J., Groenberg, H., De Laere, B., Jensen, J. B., Borre, M., Andersen, C. L., Soerensen, K. D., Maretty, L., Besenbacher, S.
10.1101/2021.06.09.447533 — Posted: 2021-06-10 — Discussion: 2022-02-11  eLife

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