COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,959 Articles (22,604 medRxiv, 8,355 bioRxiv)

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Glycans modulate the adsorption of RBD Glycoproteins on polarizable surfaces
Bosch, A., Menacho, W., Perez, R., V. Guzman, H. V.
10.1101/2025.09.30.679433 — Posted: 2025-10-01
Enhanced human antigen-specific B cell responses using in vitro 3D tonsil cultures containing stromal cells
Braham, M. V. J., de Gast, M., Babii, L., Kruijer, S., Bestebroer, T. M., Richard, M., Claireaux, M., van Ham, M. S., de Wit, J., van Els, C. A. C. M., ten Brinke, A., van Gils, M.
10.1101/2025.09.30.679470 — Posted: 2025-10-01
Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase
Georgiou, I., Robinson, C., O'Byrne, S., Matsuda, A., Grygier, P., Smith, C., O'Neill, S., Ahmad, S. A., Post, J. M., Groenewold, M. G., Urakova, N., Wanningen, P., Kresik, L., Plewka, J., Delpal, A., See, K., Eadsforth, T., Norval, S., Wierzbicka, K., Decroly, E., Saikatendu, K. S., Chang, E., Snijder, E. J., Pyrc, K., Czarna, A., Scott, D. E., Gilbert, I. H.
10.1101/2025.09.30.679521 — Posted: 2025-10-01
Rational Design of Multiclade Coronavirus Spike Immunodominant Domain Nanoparticles Elicit Broad Antibody Responses
Dzuvor, C. K. O., Moak, S., McManus, L. R., Thomas, A., Dzordzorme, A. E., Kim, T., Joseph, J., Foley, V., Gordon, I. J., Novik, L., Holman, L. A., Dropulic, L. K., McNamara, R. P., Corbett-Helaire, K. S.
10.1101/2025.10.01.679649 — Posted: 2025-10-01
Plasma nirmatrelvir and molnupiravir concentrations required for inhibition of SARS CoV-2 replication differ between rhesus macaques and humans
Avila-Ponce de Leon, U., Esmaeili, S., Owens, K., Schiffer, J. T.
10.1101/2025.09.25.678525 — Posted: 2025-10-01
Entry, replication and innate immunity evasion of BANAL-236, a SARS-CoV-2-related bat virus, in Rhinolophus and human cells
Gracias, S., Donaire-Carpio, S., Vuillier, F., Le Seach, E., Vendramini, L., Moundib, A., Rutkowska, M., Cupic, A., Juste, J., Temmam, S., Donati, F., Martinez-Romero, C., Morel, N., SCHWARTZ, O., Krogan, N., Miorin, L., Demeret, C., Roingeard, P., Munier, S., Batra, J., Garcia-Sastre, A., Caval, v., Jouvenet, N.
10.1101/2025.09.29.679146 — Posted: 2025-09-29
Pre-Omicron Immunity Generates IgG⁺ but Not IgA⁺ Memory B Cells Reactive to Omicron Spike Protein
Tsoleridis, T., Singh, I., Onion, D., Chappell, J. G., Kelly, A., Nightingale, J., Valdes, A. M., Ollivere, B. J., Hoehn, K. B., Urbanowicz, R. A., Ball, J. K.
10.1101/2025.09.26.678818 — Posted: 2025-09-29
ISG15 Differentially Modulates Clade Ib and II MPXV Infection in MEF cells
McGrail, J. P., Campana Gomez, I., Tuhkala, A., Keskitalo, S. E., Varjosalo, M., Garcia-Sastre, A., Palacios, G. F., Sanchez-Seco, M. P., Guerra, S.
10.1101/2025.09.26.678780 — Posted: 2025-09-26
A Comparative Nanomechanical Study of Antibody and Nanobody Binding to SARS-CoV-2 Variants
Cofas-Vargas, L. F., Olivos-Ramirez, G. E., Marrink, S.-J., Poma, A. B.
10.1101/2025.09.26.672567 — Posted: 2025-09-26
Late treatment initiation leads to reduced antiviral potency
Liu, X., Franco, E. J., Avedissian, S. N., Hanrahan, K. C., Guedj, J., van Hasselt, J. G. C., Brown, A. N., Martson, A.-G.
10.1101/2025.09.24.678199 — Posted: 2025-09-25

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).