Channel:  Francis Crick Institute

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Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism
Bussi, C., Heunis, T., Pellegrino, E., Bernard, E. M., Bah, N., Silva Dos Santos, M., Santucci, P., Aylan, B., Rodgers, A., Fearns, A., Mitschke, J., Moore, C., MacRae, J. I., Greco, M., Reinheckel, T., Trost, M., Gutierrez, M. G.
10.1101/2022.08.09.503288 — Posted: 2022-08-09
Improved memory CD8 T cell response to delayed vaccine boost is associated with a distinct molecular signature.
Natalini, A., Simonetti, S., Favaretto, G., Lucantonio, L., Peruzzi, G., Munoz-Ruiz, M., Kelly, G., Contino, A. M., Sbrocchi, R., Battella, S., Capone, S., Folgori, A., Nicosia, A., Santoni, A., Hayday, A. C., Di Rosa, F.
10.1101/2022.08.04.502772 — Posted: 2022-08-05
ARPC5 Isoforms and Their Regulation by Calcium-Calmodulin-N-WASP Drive Distinct Arp2/3-dependent Actin Remodeling Events in CD4 T Cells
Sadhu, L., Tsopoulidis, N., Laketa, V., Way, M., Fackler, O.
10.1101/2022.01.25.477674 — Posted: 2022-08-03
How talin allosterically activates vinculin
Franz, F., Tapia-Rojo, R., Winograd-Katz, S. E., Boujemaa-Paterski, R., Li, W., Unger, T., Albeck, S., Aponte-Santamaria, C., Garcia-Manyes, S., Medalia, O., Geiger, B., Grater, F.
10.1101/2022.08.01.502287 — Posted: 2022-08-02
cloneMap: a R package to visualise clonal heterogeneity
Frankell, A., Colliver, E., McGranahan, N., Swanton, C.
10.1101/2022.07.26.501523 — Posted: 2022-07-27
Optimal control of gene regulatory networks for morphogen-driven tissue patterning
Pezzotta, A., Briscoe, J.
10.1101/2022.07.26.501519 — Posted: 2022-07-26
Phenotypic profile of Mycobacterium tuberculosis-specific CD4 T cell responses in HIV-positive patients who develop Tuberculosis-associated Immune Reconstitution Inflammatory Syndrome
Moseki, M. R., Barber, D., Du Bruyn, E., Shey, M., Van der Plas, H., Wilkinson, R. J., Meintjes, G., Riou, C.
10.1101/2022.07.20.500909 — Posted: 2022-07-22
Transient RNA structures cause aberrant influenza virus replication and innate immune activation
French, H., Pitre, E., Oade, M. S., Elshina, E., Bisht, K., King, A., Bauer, D. L. V., te Velthuis, A. J. W.
10.1101/2022.01.25.476955 — Posted: 2022-07-22
The APE2 nuclease is essential for DNA double strand break repairby microhomology-mediated end-joining.
Fleury, H., MacEachern, M. K., Stiefel, C. M., Anand, R., Sempeck, C., Nebenfuehr, B., Dodd, B., Taylor, E., Dansoko, D., Ortega, R., Leung, J. W., Boulton, S. J., Arnoult, N.
10.1101/2022.07.21.500989 — Posted: 2022-07-22
Rarity: Discovering rare cell populations from single-cell imaging data
Marten, K., Bortolomeazzi, M., Montorsi, L., Spencer, J., Ciccarelli, F. D., Yau, C.
10.1101/2022.07.15.500256 — Posted: 2022-07-18

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