Channel:  Francis Crick Institute

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

1024 Articles

A male-essential microRNA is key for avian sex chromosome dosage compensation
Fallahshahroudi, A., Rodriguez-Montes, L., Yousefi Taemeh, S., Trost, N., Tellez, M., Ballantyne, M., Idoko-Akoh, A., Taylor, L., Sherman, A., Sorato, E., Johnsson, M., Cardoso Moreira, M., McGrew, M., Kaessmann, H.
10.1101/2024.03.06.581755 — Posted: 2024-03-07
The Molecular Landscape of Cellular Metal Ion Biology
Aulakh, S. K., Lemke, O., Szyrwiel, L., Kamrad, S., Chen, Y., Hartl, J., Muelleder, M., Nielsen, J., Ralser, M.
10.1101/2024.02.29.582718 — Posted: 2024-03-05
GLP-1 receptor agonism ameliorates Parkinsons disease through modulation of neuronal insulin signalling and glial suppression
Athauda, D., Evans, J. R., Sanchez, L., Virdi, G., Lopez Garcia, P., Wernick, A., Wagen, A., D'Sa, K., Lachica, J., Strohbuecker, S., Vecchi, G., Leighton, C., Saleeb, R. S., OShaughnessy, J., Toomey, C., Vijiaratnam, N., Girges, C., Li, Y., Mustapic, M., Ismail, K., Davies, M., Kapogiannis, D., Choi, M. L., Ryten, M., Horrocks, M. H., Greig, N. H., Foltynie, T., Gandhi, S.
10.1101/2024.02.28.582460 — Posted: 2024-02-28
A targetable PREX2/RAC1/PI3Kβ signalling axis confers resistance to clinically relevant therapeutic approaches in melanoma
Ford, C. A., Koludrovic, D., Centeno, P. P., Foth, M., Tsonou, E., Vlahov, N., Sphyris, N., Gilroy, K., Bull, C., Nixon, C., Serrels, B., Munro, A. F., Dawson, J. C., Carragher, N. O., Pavet, V., Hornigold, D. C., Dunne, P. D., Downward, J., Welch, H. C. E., Barry, S. T., Sansom, O. J., Campbell, A. D.
10.1101/2024.02.26.580534 — Posted: 2024-02-28
Sensory neuron population expansion enhances odor tracking without sensitizing projection neurons
Takagi, S., Sancer, G., Abuin, L., Stupski, S. D., Arguello, J. R., Prieto-Godino, L. L., Stern, D. L., Cruchet, S., Alvarez-Ocana, R., Wienecke, C. F. R., van Breugel, F., Jeanne, J. M., Auer, T. O., Benton, R.
10.1101/2023.09.15.556782 — Posted: 2024-02-28
TrajectoryGeometry suggests cell fate decisions involve branches rather than bifurcations
Laddach, A. C., Shapiro, M.
10.1101/2024.02.26.582231 — Posted: 2024-02-28
Alpha-synuclein aggregates trigger anti-viral immune pathways and RNA editing in human astrocytes
D'Sa, K., Choi, M. L., Wagen, A. Z., Seto-Salvia, N., Kopach, O., Evans, J. R., Rodrigues, M., Lopez-Garcia, P., Ghareeb, A., Bayne, J., Grant-Peters, M., Garcia-Ruiz, S., Chen, Z., Rodriques, S., Athauda, D., Gustavsson, E., Gagliano Taliun, S. A., Reynolds, R. H., Young, G., Strohbuecker, S., Warner, T., Rusakov, D. A., Patani, R., Bryant, C., Klenerman, D. A., Gandhi, S., Ryten, M.
10.1101/2024.02.26.582055 — Posted: 2024-02-28
Evolution and inhibition of the FIKK effector kinase family in P. falciparum
Belda, H., Bradley, D., Christodoulou, E., Nofal, S. D., Broncel, M., Jones, D. A., Davies, H., Bertran, M. T., Purkiss, A. G., Ogrodowicz, R. W., Joshi, D., O'Reilly, N., Walport, L., Claessens, A., Powell, A., House, D., Kjaer, S., Landry, C. R., Treeck, M.
10.1101/2024.02.22.581535 — Posted: 2024-02-23
Large-scale visualisation of α-synuclein oligomers in Parkinson's disease brain tissue
Andrews, R., Fu, B., Toomey, C. E., Breiter, J. C., Lachica, J., Tian, R., Beckwith, J. S., Needham, L.-M., Chant, G. J., Loiseau, C., Deconfin, A., Baspin, K., Magill, P. J., Jaunmuktane, Z., Freeman, O. J., Taylor, B. J. M., Hardy, J., Lashley, T., Ryten, M., Vendruscolo, M., Wood, N. W., Weiss, L. E., Gandhi, S., Lee, S. F.
10.1101/2024.02.17.580698 — Posted: 2024-02-19
A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory target gene expression
Gaggioli, M. R., Jones, A. G., Panagi, I., Washington, E. J., Loney, R. E., Muench, J. H., Brennan, R. G., Thurston, T. L. M., Ko, D. C.
10.1101/2024.02.14.580367 — Posted: 2024-02-14

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