Channel:  Francis Crick Institute

1,203 Articles

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Wheat pathogen Zymoseptoria tritici N-myristoyltransferase inhibitors: on-target antifungal activity and an unusual metabolic defense mechanism
Fedoryshchak, R. O., Ocasio, C. A., Strutton, B., Mattocks, J., Corran, A. J., Tate, E. W.
10.1101/2020.02.09.940536 — Posted: 2020-02-10
Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation
Dimchev, G., Amiri, B., Humphries, A. C., Schaks, M., Dimchev, V., Stradal, T. E. B., Faix, J., Krause, M., Way, M., Falcke, M., Rottner, K.
10.1101/777326 — Posted: 2020-02-05
Survival of the frequent at finite population size and mutation rate: bridging the gap between quasispecies and monomorphic regimes with a simple model
Khatri, B. S.
10.1101/375147 — Posted: 2020-02-04
Super-Beacons: open-source probes with spontaneous tuneable blinking compatible with live-cell super-resolution microscopy
Pereira, P. M., Gustafsson, N., Marsh, M., Mhlanga, M. M., Henriques, R.
10.1101/2020.01.20.912311 — Posted: 2020-02-04
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene-dose-sensitive AD-suppressor in human brain
Alic, I., Goh, P. A., Murray, A., Portelius, E., Gkanatsiou, E., Gough, G., Mok, K. Y., Koschut, D., Brunmeir, R., Yeap, Y. J., O'Brien, N. L., Groet, J., Shao, X., Havlicek, S., Dunn, N. R., Kvartsberg, H., Brinkmalm, G., Hithersay, R., Startin, C., Hamburg, S., Phillips, M., Pervushin, K., Turmaine, M., Wallon, D., Rovelet-Lecrux, A., Soininen, H., Volpi, E., Martin, J. E., Foo, J. N., Becker, D. L., Rostagno, A., Ghiso, J., Krsnik, Z., Simic, G., Kostovic, I., Mitrecic, D., LonDownS Consortium, , Francis, P. T., Blennow, K., Strydom, A., Hardy, J., Zetterberg, H., Nizetic, D.
10.1101/2020.01.29.918037 — Posted: 2020-01-31
Pyphe: A python toolbox for assessing microbial growth and cell viability in high-throughput colony screens
Kamrad, S., Rodriguez-Lopez, M., Cotobal, C., Correia-Melo, C., Ralser, M., Bahler, J.
10.1101/2020.01.22.915363 — Posted: 2020-01-23
KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity
Fournier, M., Bleuyard, J.-Y., Couturier, A. M., Ellins, J., Hester, S., Smerdon, S. J., Tora, L., Esashi, F.
10.1101/735811 — Posted: 2020-01-21
Local retinoic acid directs emergence of the extraocular muscle functional unit
Comai, G. E., Tesarova, M., Dupe, V., Rhinn, M., Vallecillo Garcia, P., da Silva, F., Feret, B., Exelby, K., Dolle, P., Carlsson, L., Pryce, B., Spitz, F., Stricker, S., Zikmund, T., Kaiser, J., Briscoe, J., Schedl, A., Ghyselinck, N. B., Schweitzer, R., Tajbakhsh, S.
10.1101/2020.01.07.897694 — Posted: 2020-01-20
Human AKTIP interacts with ESCRT proteins and functions at the midbody in cytokinesis
Merigliano, C., Burla, R., La Torre, M., Del Giudice, S., Teo, H. L., Liew, C. W., Goh, W. I., Chojnowski, A., Olmos, Y., Chiolo, I. E., Carlton, J. G., Raimondo, D., Stewart, C. L., Rhodes, D., Wright, G. D., Burke, B., Saggio, I.
10.1101/2020.01.19.911891 — Posted: 2020-01-20
Regulated repression, and not activation, governs the cell fate promoter controlling yeast meiosis
Tam, J., van Werven, F.
10.1101/2020.01.13.904912 — Posted: 2020-01-14

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