Channel:  Francis Crick Institute

1,229 Articles

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A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses
Tan, T. K., Rijal, P., Rahikainen, R., Keeble, A., Schimanski, L., Hussain, S., Harvey, R., Hayes, J., Edwards, J., McLean, R., Martini, V., Pedrera, M., Thakur, N., Conceicao, C., Dietrich, I., Shelton, H., Ludi, A. B., Wilsden, G., Browning, C., Zagrajek, A., Bialy, D., Bhat, S., Stevenson-Leggett, P., Hollinghurst, P., Tully, M., Moffat, K., Chiu, C., Waters, R., Gray, A., Azhar, M., Mioulet, V., Newman, J., Asfor, A. S., Burman, A., Crossley, S., Hammond, J., Tchilian, E., Charleston, B., Bailey, D., Tuthill, T. J., Graham, S., Malinauskas, T., Huo, J., Tree, J., Buttigieg, K., Owens, R.
10.1101/2020.08.31.275701 — Posted: 2020-08-31
Modulation of the cAMP levels with a conserved actinobacteria phosphodiesterase enzyme reduces antimicrobial tolerance in mycobacteria
Thomson, M., Nunta, K., Cheyne, A., Liu, Y., Garza-Garcia, A., Larrouy-Maumus, G.
10.1101/2020.08.26.267864 — Posted: 2020-08-26
An Integrative Analysis of the Age-Associated Genomic, Transcriptomic and Epigenetic Landscape across Cancers
Chatsirisupachai, K., Lesluyes, T., Paraoan, L., Van Loo, P., de Magalhaes, J. P.
10.1101/2020.08.25.266403 — Posted: 2020-08-25
MRE11 is crucial for malaria transmission and its absence affects expression of interconnected networks of key genes essential for life
Guttery, D., Ramaprasad, A., Ferguson, D., Zeeshan, M., Pandey, R., Brady, D., Holder, A. A., Pain, A., Tewari, R.
10.1101/2020.08.24.258657 — Posted: 2020-08-24
An optogenetic method for interrogating YAP1 and TAZ nuclear-cytoplasmic shuttling
Dowbaj, A. M., Jenkins, R. P., Heddleston, J. M., Ciccarelli, A., Fallesen, T., Hahn, K., Montagner, M., Sahai, E. M.
10.1101/2020.06.08.140228 — Posted: 2020-08-24
Active Perception during Angiogenesis: Filopodia speed up Notch selection of tip cells in silico and in vivo
Zakirov, B., Charalambous, G., Aspalter, I. M., Van-Vuuren, K., Mead, T., Harrington, K., Thuret, R., Ravasz Regan, E., Herbert, S. P., Bentley, K.
10.1101/2020.08.22.261263 — Posted: 2020-08-23
T-bet fate mapping identifies a novel ILC1-ILC2 subset in vivo
SCHROEDER, J.-H., Garrido-Mesa, N., Zabinski, T., Gallagher, A., Campbell, L., Roberts, L., Stolarczyk, E., Beattie, G., Lo, J., Iseppon, A., Moreira Heliodoro, C., Reis, R., Jenner, R., Lavender, P., Howard, J., Grencis, R., Helmby, H., Neves, J., Lord, G.
10.1101/2020.08.21.261073 — Posted: 2020-08-22
Amino acids whose intracellular levels change most during aging alter chronological lifespan of fission yeast
Rallis, C., Mulleder, M., Smith, G., Au, Y. Z., Ralser, M., Bahler, J.
10.1101/2020.08.18.256164 — Posted: 2020-08-19
Automated and unbiased classification of motor neuron phenotypes with single cell resolution in ALS tissue.
Hagemann, C., Tyzack, G. E., Taha, D. M., Devine, H., Greensmith, L., Newcombe, J., Patani, R., Serio, A., Luisier, R.
10.1101/2020.08.17.253773 — Posted: 2020-08-18
Utilizing Computational Machine Learning Tools to Understand Immunogenic Breadth in the Context of a CD8 T-Cell Mediated HIV Response
McGowan, E., Rosenthal, R., Fiore-Gartland, A., Macharia, G., Balinda, S., Kapaata, A., Muok, E., Umviligihozo, G., Dalel, J., Streatfield, C., Coutinho, H., Monaco, D., Morrison, D., Yue, L., Hunter, E., Nielsen, M., Gilmour, J., Hare, J.
10.1101/2020.08.15.250589 — Posted: 2020-08-17

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