Channel:  Francis Crick Institute

1,148 Articles

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SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export
Hall, R., Guedan, A., Yap, M. W., Young, G. R., Harvey, R., Stoye, J. P., Bishop, K. N.
10.1101/2022.02.08.479664 — Posted: 2022-02-09
Multivalent interactions essential for lentiviral integrase function
Ballandras-Colas, A., Chivukula, V., Gruszka, D. T., Shan, Z., Singh, P. K., Pye, V. E., McLean, R. K., Bedwell, G. J., Li, W., Nans, A., Cook, N. J., Fadel, H. J., Poeschla, E. M., Griffiths, D. J., Vargas, J., Taylor, I. A., Lyumkis, D., Yardimci, H., Engelman, A. N., Cherepanov, P.
10.1101/2022.01.26.477893 — Posted: 2022-01-27
Yersinia pestis genomes reveal plague in Britain 4,000 years ago
Swali, P., Schutling, R., Gilardet, A., Kelly, M., Anastasiadou, K., Glocke, I., Audsley, T., Loe, L., Fernandez-Crespo, T., Ordono, J., Walker, D., Davy, T., Silva, M., Hajdinjak, M., Bergstrom, A., Booth, T., Skoglund, P.
10.1101/2022.01.26.477195 — Posted: 2022-01-26
The rates of adult neurogenesis and oligodendrogenesis are linked to cell cycle regulation through p27-dependent gene repression of SOX2
Domingo-Muelas, A., Morante-Redolat, J. M., Moncho-Amor, V., Jordan, A., Perez-Villalba, A., Carrillo-Barbera, P., Belenguer, G., Porlan, E., Kirstein, M., Bachs, O., Ferron, S. R., Lovell-Badge, R., Farinas, I.
10.1101/2022.01.25.477676 — Posted: 2022-01-25
Tissue-intrinsic γδ T cells critically regulate Tissue-Resident Memory CD8 T cells
Munoz-Ruiz, M., Llorian, M., D'Antuono, R., Pavlova, A., Mavrigiannaki, A. M., Mckenzie, D., Garcia-Cassani, B., Iannitto, M. L., Jandke, A., Ushakov, D., Adrian C. Hayday, A.
10.1101/2022.01.19.476598 — Posted: 2022-01-21
Machine learning guided signal enrichment for ultrasensitive plasma tumor burden monitoring
Widman, A. J., Shah, M., Ogaard, N., Khamnei, C. C., Frydendahl, A., Deshpande, A., Arora, A., Zhang, M., Halmos, D., Bass, J., Langanay, T., Rajagopalan, S., Steinsnyder, Z., Liao, W., Rasmussen, M. H., Jensen, S. O., Nors, J., Therkildsen, C., Sotelo, J., Brand, R., Shah, R. H., Cheng, A. P., Maher, C., Spain, L., Krause, K., Frederick, D. T., Malbari, M. S., Marton, M., Manaa, D., Winterkorn, L., Callahan, M. K., Boland, G., Wolchok, J. D., Saxena, A., Turajlic, S., Imielinski, M., Berger, M. F., Altorki, N. K., Postow, M. A., Robine, N., Andersen, C. L., Landau, D. A.
10.1101/2022.01.17.476508 — Posted: 2022-01-20
SAIBR: A simple, platform-independent method for spectral autofluorescence correction
Rodrigues, N. T. L., Bland, T., Borrego-Pinto, J., Ng, K., Hirani, N., Gu, Y., Foo, S., Goehring, N. W.
10.1101/2022.01.19.476881 — Posted: 2022-01-20
CDC50 orthologues in Plasmodium falciparum have distinct roles in merozoite egress and trophozoite maturation
Patel, A., Nofal, S. D., Blackman, M., Baker, D. A.
10.1101/2022.01.18.476868 — Posted: 2022-01-20
Selection analysis identifies unusual clustered mutational changes in Omicron lineage BA.1 that likely impact Spike function
Martin, D. P., Lytras, S., Lucaci, A. G., Maier, W., Gruning, B., Shank, S. D., Weaver, S., MacLean, O. S., Orton, R. J., Lemey, P., Boni, M. F., Tegally, H., Harkins, G. W., Scheepers, C., Bhiman, J. N., Everatt, J., Amoako, D. G., San, J. E., Giandhari, J., Sigal, A., NGS-SA, , Williamson, C., Hsiao, N.-y., von Gottberg, A., De Klerk, A., Shafer, R. W., Robertson, D. L., Wilkinson, R. J., Sewell, B. T., Lessells, R., Nekrutenko, A., Greaney, A. J., Starr, T. N., Bloom, J. D., Murrell, B., Wilkinson, E., Gupta, R. K., de Oliveira, T., Kosakovsky Pond, S. L.
10.1101/2022.01.14.476382 — Posted: 2022-01-18
An immunogenic model of KRAS-mutant lung cancer for study of targeted therapy and immunotherapy combinations
Boumelha, J., de Carne Trecesson, S., Law, E., Romero-Clavijo, P., Coelho, M., Ng, K., Mugarza, E., Moore, C., Rana, S., Caswell, D., Murillo, M., Hancock, D., Argyris, P., Brown, W., Durfee, C., Larson, L., Vogel, R., Alejandro Suarez-Bonnet, A., Priestnall, S., East, P., Ross, S., Kassiotis, G., Molina-Arcas, M., Swanton, C., Harris, R., Downward, J.
10.1101/2020.12.22.423126 — Posted: 2022-01-17

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