Channel:  Francis Crick Institute

1,160 Articles

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Craniofacial dysmorphology in Down Syndrome is caused by increased dosage of Dyrk1a and at least three other genes
Redhead, Y., Gibbins, D., Lana-Elola, E., Watson-Scales, S., Dobson, L., Krause, M., Liu, K., Fisher, E., Green, J., Tybulewicz, V.
10.1101/2022.06.27.497841 — Posted: 2022-06-28
Comprehensive Analysis of CRISPR Base Editing Outcomes for Multimeric Protein
Kabra, M., Moosajee, M., Newby, G., Molugu, K., Saha, K., Liu, D., Pattnaik, B. R.
10.1101/2022.06.20.496792 — Posted: 2022-06-20
A computationally-enhanced hiCLIP atlas reveals Staufen1 RNA binding features and links 3' UTR structure to RNA metabolism
Chakrabarti, A. M., Iosub, I. A., Lee, F. C. Y., Ule, J., Luscombe, N. M.
10.1101/2022.06.13.495933 — Posted: 2022-06-16
Modelling mitosis with multiple phenotypes: relation to Haeckel's recapitulation law
Alexandrov, Y.
10.1101/253203 — Posted: 2022-06-15
Genome-wide functional analysis reveals key roles for kinesins in the mammalian and mosquito stages of the malaria parasite life cycle
Zeeshan, M., Rashpa, R., Ferguson, D. J. P., Abel, S., Chahine, Z., Brady, D., vaughan, s., Moores, C. A., Le Roch, K. G., Brochet, M., Holder, A. A., Tewari, R.
10.1101/2021.05.26.445751 — Posted: 2022-06-15
Crowd-sourced benchmarking of single-sample tumour subclonal reconstruction
Salcedo, A., Tarabichi, M., Buchanan, A., Espiritu, S. M. G., Zhang, H., Zhu, K., Yang, T.-H. O., Leshchiner, I., Anastassiou, D., Guan, Y., Jang, G. H., Haase, K., Deshwar, A. G., Zou, W., Umar, I., Dentro, S., Wintersinger, J. A., Chiotti, K., Demeulemeester, J., Jolly, C., Scyza, L., Ko, M., PCAWG-11 Working Group, , SMC-Het Participants, , Wedge, D. C., Morris, Q. D., Ellrot, K., Van Loo, P., Boutros, P. C.
10.1101/2022.06.14.495937 — Posted: 2022-06-15
A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite
Ramaprasad, A., Burda, P.-C., Calvani, E., Sait, A., Palma-Duran, S. A., Withers-Martinez, C., Hackett, F., MacRae, J. I., Collinson, L., Gilberger, T., Blackman, M.
10.1101/2022.06.14.496138 — Posted: 2022-06-14
Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry
Priyamvada, L., Kallemeijn, W. W., Faronato, M., Wilkins, K., Goldsmith, C. S., Cotter, C. A., Ojeda, S., Solari, R., Moss, B., Tate, E. W., Satheshkumar, P. S.
10.1101/2022.06.13.495866 — Posted: 2022-06-13
β-catenin obstructs γδ T cell immunosurveillance in colon cancer through loss of BTNL expression
Suzuki, T., Kilbey, A., Ridgway, R. A., Hayman, H., Byrne, R., Casa Rodriguez, N., Georgakopoulou, A., Chen, L., Verzi, M., Gay, D. M., Vzquez, E. G., Belnoue-Davis, H. L., Gilroy, K., Kostner, A. H., Kersten, C., Thuwajit, C., Andersen, D., Wiesheu, R., Jandke, A., Roberts, N., Blyth, K., Roseweir, A., Leedham, S. J., Dunne, P. D., Edwards, J., Hayday, A., Sansom, O. J., Coffelt, S. B.
10.1101/2022.06.10.495115 — Posted: 2022-06-12
Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis
Meier, S., Seddon, J. A., Maasdorp, E., Kleynhans, L., du Plessis, N., Loxton, A. G., Malherbe, S. T., Zak, D. E., Thompson, E., Duffy, F., Kaufmann, S. H. E., Ottenhoff, T. H. M., Scriba, T. J., Suliman, S., Sutherland, J. S., Winter, J., Kuivaniemi, H., Walzl, G., Tromp, G., GC6-74 Consortium, , Catalysis TB Biomarkers Consortium
10.1101/2022.06.10.495597 — Posted: 2022-06-11

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