Channel:  Francis Crick Institute

1,146 Articles

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CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage
Soczek, K. M., Grant, T., Rosenthal, P. B., Mondragon, A.
10.1101/397000 — Posted: 2018-08-21
P-TEFb activation by RBM7 shapes a pro-survival transcriptional response to genotoxic stress
Bugai, A., Quaresma, A. J., Friedel, C. C., Lenasi, V., Sibley, C. R., Kukanja, P., Fujinaga, K., Blasius, M., Hennig, T., Ule, J., Doelken, L., Barboric, M.
10.1101/394239 — Posted: 2018-08-17
Genome-Wide Reconstitution of Chromatin Transactions: RSC Preferentially disrupts H2A.Z-Containing Nucleosomes
Cakiroglu, A., Clapier, C., Ehrensberger, A., Darbo, E., Cairns, B., Luscombe, N., Svejstrup, J.
10.1101/394692 — Posted: 2018-08-17
A Ubiquitin-Binding Domain that Does Not Bind Ubiquitin
Lim, M., Newman, J. A., Williams, H. L., Aitkenhead, H., Gileadi, O., Svejstrup, J.
10.1101/375832 — Posted: 2018-08-15
Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity reveals structural factors responsible for differences in amino acid preferences between peptide-based substrates and covalent inhibitors.
de Vries, L. E., Sanchez, M. I., Groborz, K., Kuppens, L., Poreba, M., Lehmann, C., Yuan, F., Arastu-Kapur, S., Horn, M., Mares, M., Bogyo, M., Drag, M., Deu, E.
10.1101/246124 — Posted: 2018-08-10
Target-specific precision of CRISPR-mediated genome editing
Chakrabarti, A. M., Henser-Brownhill, T., Monserrat, J., Poetsch, A. R., Luscombe, N. M., Scaffidi, P.
10.1101/387027 — Posted: 2018-08-09
Mapping the human kinome in response to DNA damage
Owusu, M., Bannauer, P., Mourikis, A., Jones, A., Ferreira da Silva, J., Caldera, M., Wiedner, M., Lardeau, C.-H., Menche, J., Kubicek, S., Ciccarelli, F., Loizou, J.
10.1101/385344 — Posted: 2018-08-06
Nitrogen utilisation by the metabolic generalist pathogen Mycobacterium tuberculosis
Agapova, A., Hunt, D. M., Petridis, M., Garza-Garcia, A., Sohaskey, C. D., Carvalho, L. P.
10.1101/385278 — Posted: 2018-08-05
Generative adversarial networks simulate gene expression and predict perturbations in single cells
Ghahramani, A., Watt, F. M., Luscombe, N. M.
10.1101/262501 — Posted: 2018-07-30
Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation
Macpherson, J. A., Theisen, A., Masino, L., Fets, L., Driscoll, P. C., Encheva, V., Snijders, A. P., Martin, S. R., Kleinjung, J., Barran, P. E., Fraternali, F., Anastasiou, D.
10.1101/378133 — Posted: 2018-07-26

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