Channel:  Somatic Mosaicism across the Human Tissues Network (SMaHT)

38 Articles

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As48, a First-in-Class Dual-Function TREM2 Modulator: Receptor Activation and Shedding Inhibition
Cho, S., El gaamouch, F., Upadhyay, S., Nada, H., Kuncewicz, K., Gabr, M.
10.1101/2025.08.23.671919 — Posted: 2025-08-28
ToxiTaRGET: a multi-omics resource for toxicant-responsive molecular targets
Kumar, R., Fu, T., Kuntala, P. K., Fu, S., Li, D., Bartolomei, M. S., Walker, C. L., Wang, T., Zhang, B. A.
10.1101/2025.07.28.667228 — Posted: 2025-08-02
Cell-type-specific patterns and consequences of somatic mutation in development and aging brain
Kriz, A. J., Mao, S., Shao, D. D., Snellings, D. A., Andersen, R., Dong, G., Ma, C. C., Cline, H. E., Huang, A. Y., Lee, E. A., Walsh, C. A.
10.1101/2025.05.30.656844 — Posted: 2025-06-01
Image-based DNA Sequencing Encoding for Detecting Low-Mosaicism Somatic Mobile Element Insertions
Tan, M., Lin, Z., Chen, Z., Zhou, H., Park, J., He, Z., Lee, E. A., Gao, Z., Zhu, X.
10.1101/2024.11.07.619809 — Posted: 2025-05-16
Deaminase-assisted single-molecule and single-cell chromatin fiber sequencing
Swanson, E. G., Mao, Y., Mallory, B. J., Vollger, M. R., Ranchalis, J., Bohaczuk, S. C., Parmalee, N. L., Bennett, J. T., Stergachis, A. B.
10.1101/2024.11.06.622310 — Posted: 2024-11-06
Transgenerational transmission of post-zygotic mutations suggests symmetric contribution of first two blastomeres to human germline
Jang, Y., Tomasini, L., Bae, T., Szekely, A., Vaccarino, F. M., Abyzov, A.
10.1101/2024.06.18.599438 — Posted: 2024-06-22
Threshold of somatic mosaicism disrupting the brain function
Kim, J., Park, S. M., Koh, H. Y., Ko, A., Kang, H.-C., Chang, W. S., Kim, D. S., Lee, J. H.
10.1101/2023.12.30.573716 — Posted: 2023-12-30
Characterization of Cancer Evolution Landscape Based on Accurate Detection of Somatic Mutations in Single Tumor Cells
Niu, M., Zhang, Y., Luo, J., Sinson, J. C., Thompson, A. M., Zong, C.
10.1101/2023.10.09.561356 — Posted: 2023-10-09

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