Channel:  The Michael J. Fox Foundation

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

187 Articles

CSF sTREM2 correlates with CSF tau in advancing Parkinson’s disease
Wilson, E. N., Swarovski, M. S., Linortner, P., Shahid, M., Zuckerman, A. J., Wang, Q., Channappa, D., Minhas, P. S., Mhatre, S. D., Plowey, E. D., Quinn, J. F., Zabetian, C. P., Tian, L., Longo, F. M., Cholerton, B., Montine, T. J., Poston, K. L., Andreasson, K. I.
10.1101/687269 — Posted: 2019-06-30
Bach2 is a potent repressor of Nrf2-mediated antioxidant enzyme expression in dopaminergic neurons
Waxman, E. A.
10.1101/687590 — Posted: 2019-07-02
PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins
Berndsen, K., Lis, P., Yeshaw, W., Wawro, P. S., Nirujogi, R. S., Wightman, M., Macartney, T., Dorward, M., Knebel, A., Tonelli, F., Pfeffer, S. R., Alessi, D. R.
10.1101/711176 — Posted: 2019-07-22
ThX - A next-generation probe for the early detection of amyloid aggregates
Needham, L.-M., Weber, J., Varela, J. A., Fyfe, J. W. B., Do, D. T., Xu, C. K., Keenlyside, B., Cliffe, R., Klenerman, D., Dobson, C. M., Hunter, C. A., Bohndiek, S. E., Snaddon, T. N., Lee, S. F.
10.1101/713594 — Posted: 2019-07-24
LRRK2 regulates innate immune responses and neuroinflammation during Mycobacterium tuberculosis infection
Weindel, C. G., Bell, S. L., Huntington, T. E., Vail, K. J., Srinivasan, R., Patrick, K. L., Watson, R. O.
10.1101/699066 — Posted: 2019-07-26
Penetrance of Parkinson’s disease in LRRK2 p.G2019S carriers is modified by a polygenic risk score
Iwaki, H., Blauwendraat, C., Makarious, M. B., Bandres-Ciga, S., Leonard, H. L., Gibbs, J. R., Hernandez, D. G., Scholz, S. W., Faghri, F., Nalls, M. A., Singleton, A. B., International Parkinson Disease Genomics Consortium (IPDGC)
10.1101/738260 — Posted: 2019-08-16
Genetic modifiers of risk and age at onset in GBA associated Parkinson disease and Lewy body dementia
Blauwendraat, C., Reed, X., Krohn, L., Heilbron, K., Bandres-Ciga, S., Tan, M., Gibbs, J. R., Hernandez, D. G., Kumaran, R., Langston, R., Bonet Ponce, L., Alcalay, R., Hassin-Baer, S., Greenbaum, L., Iwaki, H., Leonard, H., Grenn, F. P., Ruskey, J. A., Sabir, M., Ahmed, S., Makarious, M. B., Pihlstrom, L., Toft, M., van Hilten, J. J., Marinus, J., Schulte, C., Sharma, M., Brockmann, K., Siitonen, A., Majamaa, K., Eerola-Rautio, J., Tienari, P., The 23andMe Research Team, , Pantelyat, A., Hillis-Trupe, A., Dawson, T., Rosenthal, L., Albert, M., Resnick, S. M., Ferrucci, L., Morris, C. M., Ple
10.1101/738351 — Posted: 2019-08-18
Structural basis for Rab8a GTPase recruitment of RILPL2 via LRRK2 phosphorylation of switch 2
Khan, A. R., Alessi, D. R., Waschbusch, D., Purlyte, E., Pal, P., McGrath, E.
10.1101/739813 — Posted: 2019-08-19
An assessment of LRRK2 serine 935 phosphorylation in human peripheral blood mononuclear cells in idiopathic Parkinson’s disease and G2019S LRRK2 cohorts
Padmanabhan, S., Lanz, T. A., Gorman, D., Wolfe, M., Levers, N., Joshi, N., Liong, C., Narayan, S., Alcalay, R. N., Hutten, S. J., Baptista, M. A. S., Merchant, K.
10.1101/749226 — Posted: 2019-08-29
A genome-wide genetic pleiotropy approach identified shared loci between multiple system atrophy and inflammatory bowel disease
Shadrin, A. A., Mucha, S., Ellinghaus, D., Makarious, M. B., Blauwendraat, C., Sreelatha, A. A., Heras-Garvin, A., Ding, J., Hammer, M., Foubert-Samier, A., Meissner, W. G., Rascol, O., Pavy-Le Traon, A., Frei, O. A., O'Connell, K. S., Bahrami, S., Schreiber, S., Lieb, W., Müller-Nuraysid, M., Arnold, A., Homuth, G., Schmidt, C. O., Nöthen, M. M., Hoffmann, P., Gieger, C., European Multiple System Atrophy Study Group, , Gibbs, J. R., Franke, A., Hardy, J., Wenning, G., Stefanova, N., Gasser, T., Singleton, A., Houlden, H., Scholz, S. W., Andreassen, O. A., Sharma, M.
10.1101/751354 — Posted: 2019-08-31

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