Channel:  The Michael J. Fox Foundation

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

187 Articles

Loss of one Engrailed1 allele enhances induced α-synucleinopathy
Chatterjee, D., Saiz Sanchez, D., Quansah, E., Rey, N. L., George, S., Becker, K., Madaj, Z., Steiner, J. A., Ma, J., Escobar Galvis, M. L., Kordower, J. H., Brundin, P.
10.1101/530915 — Posted: 2019-03-05
Genome-wide association study of Parkinsons disease progression biomarkers in 12 longitudinal patients cohorts
Iwaki, H., Blauwendraat, C., Leonard, H. L., Kim, J. J., Liu, G., Maple-Grodem, J., Corvol, J.-C., Pihlstrom, L., van Nimwegen, M., Hutten, S. J., Khanh-Dung, H. N., Rick, J., Eberly, S., Faghri, F., Auinger, P., Scott, K. M., Wijeyekoon, R., Van Deerlin, V. M., Hernandez, D. G., Gibbs, J. R., Chitrala, K. N., Day-Williams, A. G., Brice, A., Alves, G., Noyce, A. J., Tysnes, O.-B., Evans, J. R., Breen, D. P., Estrada, K., Wegel, C. E., Danjou, F., Simon, D. K., Andreassen, O., Ravina, B., Toft, M., Heutink, P., Bloem, B. R., Weintraub, D., Barker, R. A., Williams-Gray, C. H., van de Warrenburg
10.1101/585836 — Posted: 2019-03-27
The genetic architecture of Parkinson disease in Spain: characterizing population-specific risk, differential haplotype structures, and providing etiologic insight
Bandres Ciga, S., Ahmed, S., Sabir, M., Blauwendraat, C., Adarmes-Gomez, A., Bernal-Bernal, I., Bonilla-Toribio, M., Buiza-Rueda, D., Carrillo, F., Carrion-Claro, M., Gomez-Garre, P., Jesus, S., Labrador-Espinosa, M. A., Macias, D., Mendez-del-Barrio, C., Perinan-Tocino, T., Tejera-Parrado, C., Vargas-Gonzalez, L., Diez-Fairen, M., Alvarez, I., Tartari, J. P., Buongiorno, M. T., Aguilar, M., Gorostidi, A., Bergareche, J. A., Mondragon, E., Ruiz-Martinez, J., Dols-Icardo, O., Kulisevsky, J., Marin-Lahoz, J., Pagonabarraga, J., Pascual-Sedano, B., Ezquerra, M., Camara, A., Compta, Y., Fernandez
10.1101/609016 — Posted: 2019-04-18
Increased Dynamics of α-Synuclein Fibrils by β-Synuclein Leads to Reduced Seeding and Cytotoxicity
Yang, X., Williams, J., Yan, R., Mouradian, M. M., Baum, J.
10.1101/620401 — Posted: 2019-04-26
Experimental colitis drives enteric alpha-synuclein accumulation and Parkinson-like brain pathology
Grathwhohl, S., Quansah, E., Maroof, N., Steiner, J. A., Spycher, L., Benmansour, F., Duran-Pacheco, G., Siebourg-Polster, J., Oroszlan-Szovik, K., Remy, H., Haenggi, M., Stawiski, M., Sehlhausen, M., Maliver, P., Wolfert, A., Emrich, T., Madaj, Z., Escobar Galvis, M. L., Mueller, C., Herrmann, A., Brundin, P., Britschgi, M.
10.1101/505164 — Posted: 2019-04-28
Integration of eQTL and Parkinson’s disease GWAS data implicates 11 disease genes
Kia, D. A., Zhang, D., Guelfi, S., Manzoni, C., Hubbard, L., United Kingdom Brain Expression Consortium (UKBEC), , International PD Genomics Consortium (IPDGC), , Reynolds, R. H., Botia, J. A., Ryten, M., Ferrari, R., Lewis, P. A., Williams, N., Trabzuni, D., Hardy, J., Wood, N. W.
10.1101/627216 — Posted: 2019-05-05
The Emerging Gait Dysfunction Phenotype in Idiopathic Parkinson’s Disease
Skidmore, F., Monroe, W., Hurt, C., Nicholas, A., Gerstenecker, A., Anthony, T., Jololian, L., Cutter, G., Bashir, A., Denney, T., Standaert, D., Disbrow, E.
10.1101/632638 — Posted: 2019-05-17
Phosphorylation of Ser111 in Rab8a modulates Rabin8 dependent activation by perturbation of side chain interaction networks
Pourjafar-Dehkordi, D., Vieweg, S., Itzen, A., Zacharias, M.
10.1101/670729 — Posted: 2019-06-13
A revised 1.6 Å structure of the GTPase domain of the Parkinson’s disease-associated protein LRRK2 provides insights into mechanisms
Wu, C.-X., Liao, J., Park, Y., Hoang, N. C., Engel, V. A., Wan, L., Oh, M., Sanishvili, R., Takagi, Y., Johnson, S. M., Wang, M., Federici, M., Nichols, R. J., Bellina, A., Reed, X., Cookson, M. R., Hoang, Q. Q.
10.1101/676627 — Posted: 2019-06-23
Organotypic slice culture model demonstrates interneuronal spreading of alpha-synuclein aggregates
Elfarrash, S., Jensen, N. M., Ferreira, N., Betzer, C., Thevathasan, J. V., Diekmann, R., Adel, M., Omar, N. M., Boraie, M., Gad, S., Ries, J., Kirik, D., Nabavi, S., Jensen, P. H.
10.1101/681064 — Posted: 2019-06-24

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