Channel:  The Michael J. Fox Foundation

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

187 Articles

FILER: large-scale, harmonized FunctIonaL gEnomics Repository
Kuksa, P. P., Gangadharan, P., Katanic, Z., Kleidermacher, L., Amlie-Wolf, A., Lee, C.-Y., Qu, L., Greenfest-Allen, E., Valladares, O., Leung, Y. Y., Wang, L.-S.
10.1101/2021.01.22.427681 — Posted: 2021-06-04
Chemoproteomic-enabled characterization of small GTPase Rab1a as a target of an N-arylbenzdiimidazole ligand's rescue of Parkinson's-associated cell toxicity
Hatstat, A. K., Quan, B., Bailey, M., Fitzgerald, M. C., Reinhart, M. C., McCafferty, D. G.
10.1101/2021.05.05.442776 — Posted: 2021-05-05
Establishing gene regulatory networks from Parkinson's disease risk loci
Farrow, S. L., Schierding, W., Gokuladhas, S., Golovina, E., Fadason, T. M., Cooper, A. A., O'Sullivan, J. M.
10.1101/2021.04.08.439080 — Posted: 2021-04-09
Global ubiquitylation analysis of mitochondria in primary neurons identifies physiological Parkin targets following activation of PINK1
Antico, O., Ordureau, A., Stevens, M., Singh, F., Gierlinski, M., Barini, E., Rickwood, M., Prescott, A. R., Toth, R., Ganley, I., Harper, W., Muqit, M.
10.1101/2021.04.01.438131 — Posted: 2021-04-01
A Mendelian randomization study of glycemic and anthropometric traits and Parkinson's disease
Grover, S., Graf, R., Klein, C., Brueggemann, N., Koenig, I. R., Greco M, F. D., Sharma, M.
10.1101/2020.03.31.017566 — Posted: 2021-03-19
Multi-Modality Machine Learning Predicting Parkinsons Disease
Makarious, M. B., Leonard, H. L., Vitale, D., Iwaki, H., Sargent, L., Dadu, A., Violich, I., Hutchins, E., Saffo, D., Bandres-Ciga, S., Kim, J. J., Song, Y., Bookman, M., Nojopranoto, W., Campbell, R. H., Hashemi, S. H., Botia, J. A., Carter, J. F., Maleknia, M., Craig, D. W., Keuren-Jensen, K. V., Morris, H. R., Hardy, J. A., Blauwendraat, C., Singleton, A. B., Faghri, F., Nalls, M. A., Accelerating Medicines Program - Parkinsons Disease (AMP PD), , Global Parkinsons Genetics Program (GP2)
10.1101/2021.03.05.434104 — Posted: 2021-03-07
Transparent exploration of machine learning for biomarker discovery from proteomics and omics data
Strauss, M. T., Torun, F. M., Virreira Winter, S., Doll, S., Riese, F. M., Vorobyev, A., Müller-Reif, J. B., Geyer, P. E.
10.1101/2021.03.05.434053 — Posted: 2021-03-06
Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain
Khan, S. S., Sobu, Y., Dhekne, H. S., Tonelli, F., Berndsen, K., Alessi, D. R., Pfeffer, S. R.
10.1101/2021.03.02.433576 — Posted: 2021-03-02
Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pRab10
Wang, X., Negrou, E., Maloney, M. T., Bondar, V. V., Andrews, S. V., Montalban, M., Llapashtica, C., Maciuca, R., Nguyen, H., Solanoy, H., Arguello, A., Przybyla, L., Moerke, N. J., Huntwork-Rodriguez, S., Henry, A. G.
10.1101/2021.02.23.432545 — Posted: 2021-02-23
Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches
Ketteler, R., Tsefou, E., Walker, A. S., Clark, E. H., Hicks, A. R., Luft, C., Takeda, K., Watanabe, T., Ramazio, B., Staddon, J. M., Briston, T.
10.1101/2021.02.02.429344 — Posted: 2021-02-02

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