Channel:  The Michael J. Fox Foundation

187 Articles

Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models
Chin, R. M., Rakhit, R., Ditsworth, D., Wang, C., Bartholomeus, J., Liu, S., Mody, A., Laihsu, A., Eastes, A., Tai, C., Kim, R., Li, J., Hansberry, S., Khasnavis, S., Rafalski, V., Heerendeen, D., Garda, V., Phung, J., de Roulet, D., Ordureau, A., Harper, J. W., Johnstone, S., Stoehr, J., Hertz, N. T.
10.1101/2023.02.14.528378 — Posted: 2023-02-15
Simultaneous Determination of the Size and Shape of Single α-Synuclein Oligomers in Solution
Awasthi, S., Ying, C., Li, J., Mayer, M.
10.1101/2023.01.09.523202 — Posted: 2023-02-14
Parallel Neurodegenerative Phenotypes in Sporadic Parkinsons Disease Fibroblasts and Midbrain Dopamine Neurons
Corenblum, M. J., McRobbie-Johnson, A., Carruth, E., Bernard, K., Luo, M., Mandarino, L. J., Peterson, S., Billheimer, D., Maley, T., Eggers, E. D., Madhavan, L.
10.1101/2023.02.10.527867 — Posted: 2023-02-12
Nuclease-dead S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in patient-derived stem cell model of Parkinson's disease
Sastre, D., Zafar, F., Torres, C. A. M., Piper, D., Kirik, D., Sanders, L. H., Qi, S., Schuele, B.
10.1101/2023.01.24.525105 — Posted: 2023-01-24
Neurophysiological signatures of cortical micro-architecture
Shafiei, G., Fulcher, B. D., Voytek, B., Satterthwaite, T. D., Baillet, S., Misic, B.
10.1101/2023.01.23.525101 — Posted: 2023-01-23
Adult-specific Reelin expression alters striatal neuronal organization. Implications for neuropsychiatric disorders.
Pardo, M., Gregorio, S., Montalban, E., Pujadas, L., Elias-Tersa, A., Masachs, N., Vilchez-Acosta, A., Parent, A., Auladell, C., Girault, J. A., Vila, M., Nairn, A. C., Manso, Y., Soriano, E.
10.1101/2023.01.21.525025 — Posted: 2023-01-22
The chromatin modulating NSL complex regulates genes and pathways genetically linked to Parkinsons disease
Hicks, A. R., Reynolds, R. H., O'Callaghan, B., Garcia Ruiz, S., Gil Martinez, A. L., Botia, J. A., Plun-Favreau, H., Ryten, M.
10.1101/2023.01.16.523926 — Posted: 2023-01-18
The Foundational data initiative for Parkinsons disease (FOUNDIN-PD): enabling efficient translation from genetic maps to mechanism
Bressan, E., Reed, X., Bansal, V., Hutchins, E., Cobb, M. M., Webb, M. G., Alsop, E., Grenn, F. P., Illarionova, A., Savytska, N., Violich, I., Broeer, S., Fernandes, N., Sivakumar, R., Beilina, A., Billingsley, K., Berghausen, J., Pantazis, C. B., Pitz, V., Patel, D., Daida, K., Meechoovet, B., Reiman, R., Courtright-Lim, A., Logemann, A., Antone, J., Barch, M., Kitchen, R., Li, Y., Dalgard, C. L., The American Genome Center, , Rizzu, P., Hernandez, D. G., Hjelm, B. E., Nalls, M. A., Gibbs, J. R., Finkbeiner, S., Cookson, M. R., Van Keuren-Jensen, K., Craig, D. W., Singleton, A. B., Heutink
10.1101/2021.06.03.446785 — Posted: 2023-01-17
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue
Dhavale, D. D., Barclay, A. M., Borcik, C. G., Basore, K., Gordon, I. R., Liu, J., Milchberg, M. H., O'Shea, J. Y., Rau, M. J., Smith, Z., Sen, S., Summers, B., Smith, J. W., Warmuth, O. A., Chen, Q., Fitzpatrick, J. A. J., Schwieters, C. D., Tajkhorshid, E., Rienstra, C. M., Kotzbauer, P. T.
10.1101/2023.01.09.523303 — Posted: 2023-01-10
Diverging Parkinson's Disease Pathology between GBAN370S ,LRRK2G2019S and engineered SNCAA53T iPSC-derived Dopaminergic Neurons
Fathi, A., Bakshy, K., Zieghami, L., Fiene, R., Bradley, R., Dickerson, S., Carlson, C., Schachtele, S., Liu, J.
10.1101/2023.01.06.521264 — Posted: 2023-01-07

RSS  Channel RSS