Channel:  The Michael J. Fox Foundation

187 Articles

hipFG: High-throughput harmonization and integration pipeline for functional genomics data
Cifello, J., Kuksa, P. P., Saravanan, N., Valladares, O., Leung, Y. Y., Wang, L.-S.
10.1101/2023.04.21.537695 — Posted: 2023-04-25
Scalable, flexible carbon fiber electrode thread arrays for three-dimensional spatial profiling of neurochemical activity in deep brain structures of rodents
Xia, M., Agca, B. N., Yoshida, T., Choi, J., Amjad, U., Bose, K., Keren, N., Zukerman, S., Cima, M. J., Graybiel, A. M., Schwerdt, H. N.
10.1101/2023.04.15.537033 — Posted: 2023-04-17
A potential patient stratification biomarker for Parkinson's disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cells
Naaldijk, Y., Fernandez, B., Fasiczka, R., Fdez, E., Leghay, C., Croitoru, I., Kwok, J. B., Boulesnane, Y., Vizeneux, A., Mutez, E., Calvez, C., Destee, A., Taymans, J.-M., Vinagre Aragon, A., Bergareche Yarza, A., Padmanabhan, S., Delgado, M., Alcalay, R. N., Chatterton, Z., Dzamko, N., Halliday, G., Ruiz-Martinez, J., Chartier-Harlin, M.-C., Hilfiker, S.
10.1101/2023.04.11.536367 — Posted: 2023-04-12
Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation
Kolmogorov, M., Billingsley, K. J., Mastoras, M., Meredith, M., Monlong, J., Lorig-Roach, R., Asri, M., Alvarez Jerez, P., Malik, L., Dewan, R., Reed, X., Genner, R. M., Daida, K., Behera, S., Shafin, K., Pesout, T., Prabakaran, J., Carnevali, P., North American Brain Expression Consortium (NABEC), , Yang, J., Rhie, A., Scholz, S. W., Traynor, B. J., Miga, K. H., Jain, M., Timp, W., Phillippy, A. M., Chaisson, M., Sedlazeck, F. J., Blauwendraat, C., Paten, B.
10.1101/2023.01.12.523790 — Posted: 2023-04-05
Circular RNAs in the human brain are tailored to neuron identity and neuropsychiatric disease
Dong, X., Bai, Y., Liao, Z., Gritsch, D., Liu, X., Wang, T., Borges-Monroy, R., Ehrlich, A., Serano, G. E., Feany, M. B., Beach, T. G., Scherzer, C. R.
10.1101/2023.04.01.535194 — Posted: 2023-04-03
α-synuclein expression in response to bacterial ligands and metabolites in gut enteroendocrine cells
Hurley, M. J., Menozzi, E., Koletsi, S., Bates, R., Gegg, M. E., Chau, K.-Y., Blottiere, H. M., Macnaughtan, J., Schapira, A. H. V.
10.1101/2023.04.02.535274 — Posted: 2023-04-02
Regulation of Human PINK1 ubiquitin kinase by Serine167, Serine228 and Cysteine412 phosphorylation
Waddell, A., Ojha, H., Agarwal, S., Clarke, C., Terriente-Felix, A., Zhou, H., Kakade, P., Knebel, A., Shaw, A., Gourlay, R., Varghese, J., Soares, R., Toth, R., Macartney, T., Eyers, P., Morrice, N., Bayliss, R., Whitworth, A. J., Eyers, C., Muqit, M.
10.1101/2023.03.31.534916 — Posted: 2023-04-01
Dysregulated Wnt and NFAT signaling in a Parkinson's disease LRRK2 G2019S knock-in model
Wetzel, A., Lei, S. H., Liu, T., Hughes, M. P., Peng, Y., McKay, T., Waddington, S. N., Granno, S., Rahim, A. A., Harvey, K.
10.1101/2023.03.31.535090 — Posted: 2023-04-01
TNF-NFkB-p53 axis restricts in vivo survival of hPSC-derived dopamine neuron
Kim, T. W., Koo, S. Y., Riessland, M., Cho, H., Chaudhry, F., Kolisnyk, B., Russo, M. V., Saurat, N., Mehta, S., Garippa, R., Betel, D., Studer, L.
10.1101/2023.03.29.534819 — Posted: 2023-03-31
Splicing accuracy varies across human introns, tissues and age
Garcia-Ruiz, S., Zhang, D., Gustavsson, E. K., Rocamora-Perez, G., Grant-Peters, M., Fairbrother-Browne, A., Reynolds, R. H., Brenton, J. W., Gil-Martinez, A. L., Chen, Z., Rio, D. C., Botia, J. A., Guelfi, S., Collado-Torres, L., Ryten, M.
10.1101/2023.03.29.534370 — Posted: 2023-03-30

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