Channel:  The Michael J. Fox Foundation

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

187 Articles

A potential patient stratification biomarker for Parkinson's disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cells
Naaldijk, Y., Fernandez, B., Fasiczka, R., Fdez, E., Leghay, C., Croitoru, I., Kwok, J. B., Boulesnane, Y., Vizeneux, A., Mutez, E., Calvez, C., Destee, A., Taymans, J.-M., Vinagre Aragon, A., Bergareche Yarza, A., Padmanabhan, S., Delgado, M., Alcalay, R. N., Chatterton, Z., Dzamko, N., Halliday, G., Ruiz-Martinez, J., Chartier-Harlin, M.-C., Hilfiker, S.
10.1101/2023.04.11.536367 — Posted: 2023-04-12
Scalable, flexible carbon fiber electrode thread arrays for three-dimensional spatial profiling of neurochemical activity in deep brain structures of rodents
Xia, M., Agca, B. N., Yoshida, T., Choi, J., Amjad, U., Bose, K., Keren, N., Zukerman, S., Cima, M. J., Graybiel, A. M., Schwerdt, H. N.
10.1101/2023.04.15.537033 — Posted: 2023-04-17
Protein network analysis links the NSL complex to Parkinson's disease and mitochondrial biology
Kelly, K., Lewis, P., Plun-Favreau, H., Manzoni, C.
10.1101/2023.01.27.524249 — Posted: 2023-03-24
The chromatin modulating NSL complex regulates genes and pathways genetically linked to Parkinsons disease
Hicks, A. R., Reynolds, R. H., O'Callaghan, B., Garcia Ruiz, S., Gil Martinez, A. L., Botia, J. A., Plun-Favreau, H., Ryten, M.
10.1101/2023.01.16.523926 — Posted: 2023-01-18
Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models
Chin, R. M., Rakhit, R., Ditsworth, D., Wang, C., Bartholomeus, J., Liu, S., Mody, A., Laihsu, A., Eastes, A., Tai, C., Kim, R., Li, J., Hansberry, S., Khasnavis, S., Rafalski, V., Heerendeen, D., Garda, V., Phung, J., de Roulet, D., Ordureau, A., Harper, J. W., Johnstone, S., Stoehr, J., Hertz, N. T.
10.1101/2023.02.14.528378 — Posted: 2023-02-15
Prospective role of PAK6 and 14-3-3 gamma as biomarkers for Parkinson's disease
Giusto, E., Maistrello, L., Iannotta, L., Giusti, V., Iovino, L., Bandopadhyay, R., Antonini, A., Bubacco, L., Barresi, R., Plotegher, N., Greggio, E., Civiero, L.
10.1101/2023.04.28.538525 — Posted: 2023-04-28
Tau protein aggregation associated with SARS-CoV-2 main protease
Eberle, R. J., Coronado, M. A., Gering, I., Korostov, K., Stefanski, A., Stuehler, K., Kraemer-Schulien, V., Bloemeke, L., Bannach, O., Willbold, D.
10.1101/2023.03.04.531078 — Posted: 2023-03-06
TNF-NFkB-p53 axis restricts in vivo survival of hPSC-derived dopamine neuron
Kim, T. W., Koo, S. Y., Riessland, M., Cho, H., Chaudhry, F., Kolisnyk, B., Russo, M. V., Saurat, N., Mehta, S., Garippa, R., Betel, D., Studer, L.
10.1101/2023.03.29.534819 — Posted: 2023-03-31
Genome-wide screen reveals Rab12 GTPase as a critical activator of pathogenic LRRK2 kinase
Dhekne, H. S., Tonelli, F., Yeshaw, W. M., Chiang, C. Y., Limouse, C., Jaimon, E., Purlyte, E., Alessi, D. R., Pfeffer, S. R.
10.1101/2023.02.17.529028 — Posted: 2023-02-18
Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation
Kolmogorov, M., Billingsley, K. J., Mastoras, M., Meredith, M., Monlong, J., Lorig-Roach, R., Asri, M., Alvarez Jerez, P., Malik, L., Dewan, R., Reed, X., Genner, R. M., Daida, K., Behera, S., Shafin, K., Pesout, T., Prabakaran, J., Carnevali, P., North American Brain Expression Consortium (NABEC), , Yang, J., Rhie, A., Scholz, S. W., Traynor, B. J., Miga, K. H., Jain, M., Timp, W., Phillippy, A. M., Chaisson, M., Sedlazeck, F. J., Blauwendraat, C., Paten, B.
10.1101/2023.01.12.523790 — Posted: 2023-04-05

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