Channel:  The Michael J. Fox Foundation

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

187 Articles

Distinct roles for RAB10 and RAB29 in pathogenic LRRK2-mediated endolysosomal trafficking alterations
Rivero-Rios, P., Romo-Lozano, M., Fernandez, B., Fdez, E., Hilfiker, S.
10.1101/2020.06.20.163063 — Posted: 2020-06-20
Genome-Wide Association Study Meta-Analysis for Parkinson Disease Motor Subtypes
Alfradique-Dunham, I., Al-Ouran, R., von Coelln, R., Blauwendraat, C., Hill, E., Luo, L., Stillwell, A., Young, E., Tan, M., Liao, C., Hernandez, D., Pihlstrom, L., Grosset, D., Shulman, L. M., Liu, Z., Rouleau, G., International Parkinson's Disease Genomics Consortium, , Nalls, M. A., Singleton, A., Morris, H., Jankovic, J., Shulman, J. M.
10.1101/2020.06.26.174276 — Posted: 2020-06-27
Pathway-specific deregulation of striatal excitatory synapses in LRRK2 mutations
Chen, C., Soto, G., Bannon, N., Kang, S., Kozorovitskiy, Y., Parisiadou, L.
10.1101/2020.01.03.894410 — Posted: 2020-07-03
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into the complex genetic architecture
Chia, R., Sabir, M. S., Bandres-Ciga, S., Saez-Atienzar, S., Reynolds, R. H., Gustavsson, E., Walton, R. L., Ahmed, S., Viollet, C., Ding, J., Makarious, M. B., Diez-Fairen, M., Portley, M. K., Shah, Z., Abramzon, Y., Hernandez, D. G., Blauwendraat, C., Stone, D. J., Eicher, J., Parkkinen, L., Ansorge, O., Clark, L., Honig, L. S., Marder, K., Lemstra, A., St. George-Hyslop, P., Londos, E., Morgan, K., Lashley, T., Warner, T. T., Jaunmuktane, Z., Galasko, D., Santana, I., Tienari, P., Myllykangas, L., Oinas, M., Cairns, N. J., Morris, J. C., Halliday, G. M., Van Deerlin, V. M., Trojanowski, J.
10.1101/2020.07.06.185066 — Posted: 2020-07-06
Poly(ADP-ribose) induces α-synuclein aggregation in neuronal-like cells andinteracts with phosphorylated α-synuclein in post mortem PD samples
Puentes, L. N., Lengyel-Zhand, Z., Lee, J. Y., Hsieh, C.-J., Schneider, M. E., Edwards, K. J., Luk, K. C., Lee, V. M.- Y., Trojanowski, J. Q., Mach, R. H.
10.1101/2020.04.08.032250 — Posted: 2020-07-06
LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation
Pischedda, F., Cirnaru, M. D., Ponzoni, L., Sandre, M., Biosa, A., Carrion, M. P., Marin, O., Morari, M., Pan, L., Greggio, E., Bandopadhyay, R., Sala, M., Piccoli, G.
10.1101/721266 — Posted: 2020-07-10
Associations of Mitochondrial Genomic Variation with Corticobasal Degeneration, Progressive Supranuclear Palsy, and Neuropathological Tau Measures
Rebecca R Valentino, Nikoleta Tamvaka, Michael G Heckman, Patrick W Johnson, Alexandra I Soto-Beasley, Ronald L Walton, Shunsuke Koga, Ryan J Uitti, Zbigniew K Wszolek, Dennis W Dickson, Owen A Ross
10.1101/2020.07.10.196097 — Posted: 2020-07-11
Discordant transcriptional signatures of mitochondrial genes in Parkinson's disease human myeloid cells
Navarro, E., Udine, E., de Paiva Lopes, K., Parks, M., Riboldi, G., Schilder, B. M., Humphrey, J., Snijders, G. J. L., Vialle, R. A., Zhuang, M., Sikder, T., Argyrou, C., Allan, A., Chao, M., Farrell, K., Henderson, B., Simon, S., Raymond, D., Elango, S., Ortega, R. A., Shanker, V., Swan, M., Zhu, C., Ramdhani, R., Walker, R. H., Tse, W., Sano, M., Pereira, A. C., Ahfeldt, T., Goate, A. M., Bressman, S., Crary, J. F., de Witte, L., Frucht, S., Saunders-Pullman, R., Raj, T.
10.1101/2020.07.20.212407 — Posted: 2020-07-22
Modeling Alpha-Synuclein Pathology in a Human Brain-Chip to Assess Blood-Brain Barrier Disruption in Parkinson's Disease
Pediaditakis, I., Kodella, K. R., Manatakis, D. V., Hinojosa, C. D., Manolakos, E. S., Rubin, L. L., Hamilton, G. A., Karalis, K.
10.1101/2020.07.22.207340 — Posted: 2020-07-27
Pathogenic LRRK2 R1441C mutation is associated with striatal alterations
Xenias, H., Chen, C., Kang, S., Cherian, S., Situ, X., Shanmugasundaram, B., Scesa, G., Chan, C. S., Parisiadou, L.
10.1101/2020.03.11.986455 — Posted: 2020-07-29

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