Channel:  The Michael J. Fox Foundation

187 Articles

A Novel Method for Calculating Beta Band Burst Durations in Parkinson's Disease Using a Physiological Baseline
Anderson, R. W., Neuville, R. S., Kehnemouyi, Y. M., Anidi, C. M., Petrucci, M. N., Parker, J. E., Velisar, A., Bronte-Stewart, H. M.
10.1101/2020.03.25.008185 — Posted: 2020-03-26
PathoFact: A pipeline for the prediction of virulence factors and antimicrobial resistance genes in metagenomic data
de Nies, L., Lopes, S., Heintz-Buschart, A., Laczny, C. C., May, P., Wilmes, P.
10.1101/2020.03.24.006148 — Posted: 2020-03-25
The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor complex are responsible for the cellular uptake of Aβ42 and its protein aggregates
Riad, A., Lengyel-Zhand, Z., Zeng, C., Weng, C.-C., Lee, V. M.- Y., Trojanowski, J. Q., Mach, R. H.
10.1101/2020.02.19.956359 — Posted: 2020-02-20
Crowdsourcing digital health measures to predict Parkinson's disease severity: the Parkinson's Disease Digital Biomarker DREAM Challenge
Sieberts, S. K., Schaff, J., Duda, M., Pataki, B. A., Sun, M., Snyder, P., Daneault, J.-F., Parisi, F., Costante, G., Rubin, U., Banda, P., Chae, Y., Neto, E. C., Dorsey, R., Aydın, Z., Chen, A., Elo, L. L., Espino, C., Glaab, E., Goan, E., Golabchi, F. N., Görmez, Y., Jaakkola, M. K., Jonnagaddala, J., KLEn, R., Li, D., McDaniel, C., Perrin, D., Rad, N. M., Rainaldi, E., Sapienza, S., Schwab, P., Shokhirev, N., Venäläinen, M. S., Vergara-Diaz, G., Zhang, Y., Parkinson's Disease Digital Biomarker Challenge Consortium, , Wang, Y., Guan, Y., Brunner, D., Bonato, P., Mangravite, L. M., Omberg
10.1101/2020.01.13.904722 — Posted: 2020-02-20
Oxidative Modifications of Parkin Underlie its Selective Neuroprotection in Adult Human Brain
Tokarew, J. M., El-Kodsi, D. N., Lengacher, N. A., Fehr, T. K., Nguyen, A. P., O'Nuallain, B., Jin, M., Khan, J. M., Ng, A. C.-H., Li, J., Jiang, Q., Zhang, M., Wang, L., Sengupta, R., Barber, K. R., Tran, A., Zandee, S., Dong, X., Scherzer, C. R., Prat, A., Tsai, E., Takanashi, M., Hattori, N., Chan, J. A., West, A. B., Holmgren, A., Puente, L., Shaw, G. S., Toth, G., Woulfe, J. M., Taylor, P., Tomlinson, J. J., Schlossmacher, M. G.
10.1101/2020.02.19.953034 — Posted: 2020-02-20
Sexually dimorphic responses to MPTP found in microglia, inflammation and gut microbiota in a progressive monkey model of Parkinson's disease
Joers, V., Masilamoni, G., Kempf, D. J., Weiss, A. R., Rotterman, T., Murray, B., Yalcin-Cakmakli, G., Voll, R., Goodman, M. M., Howell, L., Bachevalier, J., Green, S., Naqib, A., Shaikh, M., Engen, P., Keshavarzian, A., Barnum, C. J., Nye, J. A., Smith, Y., Tansey, M. G.
10.1101/2020.01.30.925883 — Posted: 2020-01-31
Absence of Sac2/INPP5F enhances the phenotype of a Parkinson's disease mutation of synaptojanin 1
Cao, M., Park, D., Wu, Y., De Camilli, P.
10.1101/2020.01.21.914317 — Posted: 2020-01-21
SparkINFERNO: A scalable high-throughput pipeline for inferring molecular mechanisms of non-coding genetic variants
Kuksa, P. P., Lee, C.-Y., Amlie-Wolf, A., Gangadharan, P., Mlynarski, E. E., Chou, Y.-F., Lin, H.-J., Issen, H., Greenfest-Allen, E., Valladares, O., Leung, Y. Y., Wang, L.-S.
10.1101/2020.01.07.897579 — Posted: 2020-01-08
Human Tau Isoform Aggregation and Selective Detection of Misfolded Tau from Post-Mortem Alzheimer's Disease Brains
Wu, L., Wang, Z., Lad, S., Dougharty, D., Madhavan, S., Marcus, M., Henderson, F., Ray, W. K., Tan, C., Siedlak, S., Li, J., Helm, R. F., Zhu, X., Bloom, G. S., Zou, W., Xu, B.
10.1101/2019.12.31.876946 — Posted: 2020-01-02
Dopaminergic Neurodegeneration Induced by Parkinson's Disease-Linked G2019S LRRK2 is Dependent on Kinase and GTPase Activity
Nguyen, A. P. T., Tsika, E., Kelly, K., Chen, X., Levine, N., West, A. B., Boularand, S., Barneoud, P., Moore, D. J.
10.1101/2019.12.17.879759 — Posted: 2019-12-18

RSS  Channel RSS