Channel:  The Michael J. Fox Foundation

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

187 Articles

Sexually dimorphic responses to MPTP found in microglia, inflammation and gut microbiota in a progressive monkey model of Parkinson's disease
Joers, V., Masilamoni, G., Kempf, D. J., Weiss, A. R., Rotterman, T., Murray, B., Yalcin-Cakmakli, G., Voll, R., Goodman, M. M., Howell, L., Bachevalier, J., Green, S., Naqib, A., Shaikh, M., Engen, P., Keshavarzian, A., Barnum, C. J., Nye, J. A., Smith, Y., Tansey, M. G.
10.1101/2020.01.30.925883 — Posted: 2020-01-31
The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor complex are responsible for the cellular uptake of Aβ42 and its protein aggregates
Riad, A., Lengyel-Zhand, Z., Zeng, C., Weng, C.-C., Lee, V. M.- Y., Trojanowski, J. Q., Mach, R. H.
10.1101/2020.02.19.956359 — Posted: 2020-02-20
Oxidative Modifications of Parkin Underlie its Selective Neuroprotection in Adult Human Brain
Tokarew, J. M., El-Kodsi, D. N., Lengacher, N. A., Fehr, T. K., Nguyen, A. P., O'Nuallain, B., Jin, M., Khan, J. M., Ng, A. C.-H., Li, J., Jiang, Q., Zhang, M., Wang, L., Sengupta, R., Barber, K. R., Tran, A., Zandee, S., Dong, X., Scherzer, C. R., Prat, A., Tsai, E., Takanashi, M., Hattori, N., Chan, J. A., West, A. B., Holmgren, A., Puente, L., Shaw, G. S., Toth, G., Woulfe, J. M., Taylor, P., Tomlinson, J. J., Schlossmacher, M. G.
10.1101/2020.02.19.953034 — Posted: 2020-02-20
Crowdsourcing digital health measures to predict Parkinson's disease severity: the Parkinson's Disease Digital Biomarker DREAM Challenge
Sieberts, S. K., Schaff, J., Duda, M., Pataki, B. A., Sun, M., Snyder, P., Daneault, J.-F., Parisi, F., Costante, G., Rubin, U., Banda, P., Chae, Y., Neto, E. C., Dorsey, R., Aydın, Z., Chen, A., Elo, L. L., Espino, C., Glaab, E., Goan, E., Golabchi, F. N., Görmez, Y., Jaakkola, M. K., Jonnagaddala, J., KLEn, R., Li, D., McDaniel, C., Perrin, D., Rad, N. M., Rainaldi, E., Sapienza, S., Schwab, P., Shokhirev, N., Venäläinen, M. S., Vergara-Diaz, G., Zhang, Y., Parkinson's Disease Digital Biomarker Challenge Consortium, , Wang, Y., Guan, Y., Brunner, D., Bonato, P., Mangravite, L. M., Omberg
10.1101/2020.01.13.904722 — Posted: 2020-02-20
PathoFact: A pipeline for the prediction of virulence factors and antimicrobial resistance genes in metagenomic data
de Nies, L., Lopes, S., Heintz-Buschart, A., Laczny, C. C., May, P., Wilmes, P.
10.1101/2020.03.24.006148 — Posted: 2020-03-25
A Novel Method for Calculating Beta Band Burst Durations in Parkinson's Disease Using a Physiological Baseline
Anderson, R. W., Neuville, R. S., Kehnemouyi, Y. M., Anidi, C. M., Petrucci, M. N., Parker, J. E., Velisar, A., Bronte-Stewart, H. M.
10.1101/2020.03.25.008185 — Posted: 2020-03-26
Pathogenic LRRK2 regulates ciliation probability upstream of Tau Tubulin kinase 2
Sobu, Y., Wawro, P. S., Dhekne, H. S., Pfeffer, S. R.
10.1101/2020.04.07.029983 — Posted: 2020-04-08
Control of mammalian brain aging by the unfolded protein response (UPR)
Cabral Miranda, F., Tamburini, G., Martinez, G., Medinas, D., Gerakis, Y., Miedema, T., Duran-Aniotz, C., Ardilles, A., Ibaceta, C., Sabusap, C., Bermedo-Garcia, F., Adamson, S., Vitangcol, K., Huerta, H., Zhang, X., Nakamura, T., Sardi, P., Lipton, S., Kennedy, B., Cardenas, J. C., Palacios, A., Plate, L., Henriquez, J. P., Hetz, C.
10.1101/2020.04.13.039172 — Posted: 2020-04-14
A novel USP30 inhibitor recapitulates genetic loss of USP30 and sets the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Rusilowicz-Jones, E., Jardine, J., Kallinos, A., Pinto-Fernandez, A., Guenther, F., Giurrandino, M., Barone, F. G., McCarron, K., Burke, C. J., Murad, A., Martinez, A., Marcassa, E., Gersch, M., Buckmelter, A., Kayser-Bricker, K., Lamoliatte, F., Gajbhiye, A., Davis, S., Scott, H. C., Murphy, E., England, K., Mortiboys, H., Komander, D., Trost, M., Kessler, B. M., Ioannidis, S., Ahlijanian, M., Urbe, S., Clague, M. J.
10.1101/2020.04.16.044206 — Posted: 2020-04-20
LRRK2-phosphorylated Rab10 sequesters Myosin Va with RILPL2 during ciliogenesis blockade
Yanatori, I., Dhekne, H. S., Vides, E. G., Sobu, Y., Diez, F., Pfeffer, S. R.
10.1101/2020.04.28.065664 — Posted: 2020-04-28

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