Channel:  The Michael J. Fox Foundation

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

187 Articles

Protein synthesis is suppressed in sporadic and familial Parkinson's Disease by LRRK2
Deshpande, P., Flinkman, D., Hong, Y., Goltseva, E., Siino, V., Sun, L., Peltonen, S., Elo, L., Kaasinen, V., James, P., Coffey, E. T.
10.1101/2020.04.27.053694 — Posted: 2020-04-28
Parkinson Disease-Linked Parkin Mediates Redox Reactions That Lower Oxidative Stress In Mammalian Brain
El Kodsi, D. N., Tokarew, J. M., Sengupta, R., Lengacher, N. A., Ng, A. C., Boston, H., Jiang, Q., Palmberg, C., Pileggi, C., Shutinoski, B., Li, J., Nguyen, A. P., Fehr, T. K., Im, D. S., Callaghan, S., Park, D. S., LaVoie, M. J., Chan, J. A., Takanashi, M., Hattori, N., Ratan, R. R., Zecca, L., Puente, L., Shaw, G. S., Harper, M.-E., Holmgren, A., Tomlinson, J. J., Schlossmacher, M. G.
10.1101/2020.04.26.062380 — Posted: 2020-05-03
Large-scale pathway-specific polygenic risk, transcriptomic community networks and functional inferences in Parkinson disease
Bandres-Ciga, S., Saez-Atienzar, S., Kim, J. J., Makarious, M., Faghri, F., Diez-Fairen, M., Iwaki, H., Leonard, H., Botia, J. A., Ryten, M., Hernandez, D., Gibbs, R., Ding, J., Gan-Or, Z., Noyce, A., Pihlstrom, L., Torkamani, A., Scholz, S. W., Traynor, B., Ehrlich, D., Scherzer, C. R., Bookman, M., Cookson, M. R., Blauwendraat, C., Nalls, M. A., Singleton, A., International Parkinson's Disease Genomics Consortium
10.1101/2020.05.05.079228 — Posted: 2020-05-06
Protection from α-synuclein-induced dopaminergic neurodegeneration by overexpression of the mitochondrial import receptor TOM20 in the rat midbrain
De Miranda, B. R., Rocha, E. M., Castro, S., Greenamyre, J. T.
10.1101/2020.05.11.089078 — Posted: 2020-05-13
Fast purification of recombinant monomeric amyloid-β from E. coli and amyloid-β-mCherry aggregates from mammalian cells
Stephens, A. D., Lu, M., Kaminski Schierle, G. S.
10.1101/2020.05.13.093534 — Posted: 2020-05-15
Purification of recombinant α-Synuclein: a comparison of commonly used protocols
Stephens, A. D., Matak-Vinkovic, D., Kaminski Schierle, G. S.
10.1101/2020.05.13.093286 — Posted: 2020-05-15
Deep sncRNA-seq of the PPMI cohort to study Parkinson's disease progression
Kern, F., Fehlmann, T., Violich, I., Alsop, E., Hutchins, E., Kahraman, M., Grammes, N. L., Guimaraes, P., Backes, C., Poston, K., Casey, B., Balling, R., Geffers, L., Krueger, R., Galasko, D., Mollenhauer, B., Meese, E., Wyss-Coray, T., Craig, D. W., Van Keuren-Jensen, K., Keller, A.
10.1101/2020.06.01.127092 — Posted: 2020-06-01
Characterization of small molecule induced changes in Parkinson's-related trafficking via the Nedd4 ubiquitin signaling cascade
Hatstat, A. K., Ahrendt, H. D., Foster, M. W., Mayne, L., Moseley, M. A., Englander, S. W., McCafferty, D. G.
10.1101/2020.06.01.128348 — Posted: 2020-06-02
Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles
Huang, Y., Cheng, L., Turchinovich, A., Mahairaki, V., Troncoso, J. C., Pletnikov, O., Haughey, N. J., Vella, L. J., Hill, A. F., Zheng, L., Witwer, K. W.
10.1101/2020.02.10.940999 — Posted: 2020-06-06
Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies
Hardenberg, M. C., Sinnige, T., Casford, S., Dada, S., Poudel, C., Robinson, L., Fuxreiter, M., Kaminski, C. F., Kaminski Schierle, G. S., Nollen, E. A. A., Dobson, C. M., Vendruscolo, M.
10.1101/2020.06.08.140798 — Posted: 2020-06-10

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