Channel:  The Michael J. Fox Foundation

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

187 Articles

Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain
Khan, S. S., Sobu, Y., Dhekne, H. S., Tonelli, F., Berndsen, K., Alessi, D. R., Pfeffer, S. R.
10.1101/2021.03.02.433576 — Posted: 2021-03-02
Transparent exploration of machine learning for biomarker discovery from proteomics and omics data
Strauss, M. T., Torun, F. M., Virreira Winter, S., Doll, S., Riese, F. M., Vorobyev, A., Müller-Reif, J. B., Geyer, P. E.
10.1101/2021.03.05.434053 — Posted: 2021-03-06
Multi-Modality Machine Learning Predicting Parkinsons Disease
Makarious, M. B., Leonard, H. L., Vitale, D., Iwaki, H., Sargent, L., Dadu, A., Violich, I., Hutchins, E., Saffo, D., Bandres-Ciga, S., Kim, J. J., Song, Y., Bookman, M., Nojopranoto, W., Campbell, R. H., Hashemi, S. H., Botia, J. A., Carter, J. F., Maleknia, M., Craig, D. W., Keuren-Jensen, K. V., Morris, H. R., Hardy, J. A., Blauwendraat, C., Singleton, A. B., Faghri, F., Nalls, M. A., Accelerating Medicines Program - Parkinsons Disease (AMP PD), , Global Parkinsons Genetics Program (GP2)
10.1101/2021.03.05.434104 — Posted: 2021-03-07
A Mendelian randomization study of glycemic and anthropometric traits and Parkinson's disease
Grover, S., Graf, R., Klein, C., Brueggemann, N., Koenig, I. R., Greco M, F. D., Sharma, M.
10.1101/2020.03.31.017566 — Posted: 2021-03-19
Global ubiquitylation analysis of mitochondria in primary neurons identifies physiological Parkin targets following activation of PINK1
Antico, O., Ordureau, A., Stevens, M., Singh, F., Gierlinski, M., Barini, E., Rickwood, M., Prescott, A. R., Toth, R., Ganley, I., Harper, W., Muqit, M.
10.1101/2021.04.01.438131 — Posted: 2021-04-01
Establishing gene regulatory networks from Parkinson's disease risk loci
Farrow, S. L., Schierding, W., Gokuladhas, S., Golovina, E., Fadason, T. M., Cooper, A. A., O'Sullivan, J. M.
10.1101/2021.04.08.439080 — Posted: 2021-04-09
Chemoproteomic-enabled characterization of small GTPase Rab1a as a target of an N-arylbenzdiimidazole ligand's rescue of Parkinson's-associated cell toxicity
Hatstat, A. K., Quan, B., Bailey, M., Fitzgerald, M. C., Reinhart, M. C., McCafferty, D. G.
10.1101/2021.05.05.442776 — Posted: 2021-05-05
The Foundational data initiative for Parkinsons disease (FOUNDIN-PD): enabling efficient translation from genetic maps to mechanism
Bressan, E., Reed, X., Bansal, V., Hutchins, E., Cobb, M. M., Webb, M. G., Alsop, E., Grenn, F. P., Illarionova, A., Savytska, N., Violich, I., Broeer, S., Fernandes, N., Sivakumar, R., Beilina, A., Billingsley, K., Berghausen, J., Pantazis, C. B., Pitz, V., Patel, D., Daida, K., Meechoovet, B., Reiman, R., Courtright-Lim, A., Logemann, A., Antone, J., Barch, M., Kitchen, R., Li, Y., Dalgard, C. L., The American Genome Center, , Rizzu, P., Hernandez, D. G., Hjelm, B. E., Nalls, M. A., Gibbs, J. R., Finkbeiner, S., Cookson, M. R., Van Keuren-Jensen, K., Craig, D. W., Singleton, A. B., Heutink
10.1101/2021.06.03.446785 — Posted: 2023-01-17
FILER: large-scale, harmonized FunctIonaL gEnomics Repository
Kuksa, P. P., Gangadharan, P., Katanic, Z., Kleidermacher, L., Amlie-Wolf, A., Lee, C.-Y., Qu, L., Greenfest-Allen, E., Valladares, O., Leung, Y. Y., Wang, L.-S.
10.1101/2021.01.22.427681 — Posted: 2021-06-04
PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7 to suppress p53 dependent neurodegeneration
Huo, Y., Sawant, A., Tan, Y., Mahdi, A. H., Li, T., Ma, H., Bhatt, V., Yan, R., Coleman, J., Dreyfus, C. F., Guo, J. Y., Mouradian, M. M., White, E., Xia, B.
10.1101/2021.06.07.447248 — Posted: 2021-06-07

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