Channel:  The Michael J. Fox Foundation

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

187 Articles

LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation
Pischedda, F., Cirnaru, M. D., Ponzoni, L., Sandre, M., Biosa, A., Carrion, M. P., Marin, O., Morari, M., Pan, L., Greggio, E., Bandopadhyay, R., Sala, M., Piccoli, G.
10.1101/721266 — Posted: 2020-07-10
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into the complex genetic architecture
Chia, R., Sabir, M. S., Bandres-Ciga, S., Saez-Atienzar, S., Reynolds, R. H., Gustavsson, E., Walton, R. L., Ahmed, S., Viollet, C., Ding, J., Makarious, M. B., Diez-Fairen, M., Portley, M. K., Shah, Z., Abramzon, Y., Hernandez, D. G., Blauwendraat, C., Stone, D. J., Eicher, J., Parkkinen, L., Ansorge, O., Clark, L., Honig, L. S., Marder, K., Lemstra, A., St. George-Hyslop, P., Londos, E., Morgan, K., Lashley, T., Warner, T. T., Jaunmuktane, Z., Galasko, D., Santana, I., Tienari, P., Myllykangas, L., Oinas, M., Cairns, N. J., Morris, J. C., Halliday, G. M., Van Deerlin, V. M., Trojanowski, J.
10.1101/2020.07.06.185066 — Posted: 2020-07-06
Poly(ADP-ribose) induces α-synuclein aggregation in neuronal-like cells andinteracts with phosphorylated α-synuclein in post mortem PD samples
Puentes, L. N., Lengyel-Zhand, Z., Lee, J. Y., Hsieh, C.-J., Schneider, M. E., Edwards, K. J., Luk, K. C., Lee, V. M.- Y., Trojanowski, J. Q., Mach, R. H.
10.1101/2020.04.08.032250 — Posted: 2020-07-06
Pathway-specific deregulation of striatal excitatory synapses in LRRK2 mutations
Chen, C., Soto, G., Bannon, N., Kang, S., Kozorovitskiy, Y., Parisiadou, L.
10.1101/2020.01.03.894410 — Posted: 2020-07-03
Genome-Wide Association Study Meta-Analysis for Parkinson Disease Motor Subtypes
Alfradique-Dunham, I., Al-Ouran, R., von Coelln, R., Blauwendraat, C., Hill, E., Luo, L., Stillwell, A., Young, E., Tan, M., Liao, C., Hernandez, D., Pihlstrom, L., Grosset, D., Shulman, L. M., Liu, Z., Rouleau, G., International Parkinson's Disease Genomics Consortium, , Nalls, M. A., Singleton, A., Morris, H., Jankovic, J., Shulman, J. M.
10.1101/2020.06.26.174276 — Posted: 2020-06-27
Distinct roles for RAB10 and RAB29 in pathogenic LRRK2-mediated endolysosomal trafficking alterations
Rivero-Rios, P., Romo-Lozano, M., Fernandez, B., Fdez, E., Hilfiker, S.
10.1101/2020.06.20.163063 — Posted: 2020-06-20
Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies
Hardenberg, M. C., Sinnige, T., Casford, S., Dada, S., Poudel, C., Robinson, L., Fuxreiter, M., Kaminski, C. F., Kaminski Schierle, G. S., Nollen, E. A. A., Dobson, C. M., Vendruscolo, M.
10.1101/2020.06.08.140798 — Posted: 2020-06-10
Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles
Huang, Y., Cheng, L., Turchinovich, A., Mahairaki, V., Troncoso, J. C., Pletnikov, O., Haughey, N. J., Vella, L. J., Hill, A. F., Zheng, L., Witwer, K. W.
10.1101/2020.02.10.940999 — Posted: 2020-06-06
Characterization of small molecule induced changes in Parkinson's-related trafficking via the Nedd4 ubiquitin signaling cascade
Hatstat, A. K., Ahrendt, H. D., Foster, M. W., Mayne, L., Moseley, M. A., Englander, S. W., McCafferty, D. G.
10.1101/2020.06.01.128348 — Posted: 2020-06-02
Deep sncRNA-seq of the PPMI cohort to study Parkinson's disease progression
Kern, F., Fehlmann, T., Violich, I., Alsop, E., Hutchins, E., Kahraman, M., Grammes, N. L., Guimaraes, P., Backes, C., Poston, K., Casey, B., Balling, R., Geffers, L., Krueger, R., Galasko, D., Mollenhauer, B., Meese, E., Wyss-Coray, T., Craig, D. W., Van Keuren-Jensen, K., Keller, A.
10.1101/2020.06.01.127092 — Posted: 2020-06-01

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