Channel:  Babraham Institute

154 Articles

A single-cell transcriptomics CRISPR-activation screen identifies new epigenetic regulators of zygotic genome activation
Alda-Catalinas, C., Bredikhin, D., Hernando-Herraez, I., Kubinyecz, O., Santos, F., Eckersley-Maslin, M. A., Stegle, O., Reik, W.
10.1101/741371 — Posted: 2019-08-21
Follicular regulatory T cells can access the germinal centre independently of CXCR5
Vanderleyden, I., Fra-Bido, S., Innocentin, S., Okkenhaug, H., Evans-Bailey, N., Pierson, W., Linterman, M.
10.1101/641589 — Posted: 2019-05-17
An intergenic non-coding RNA promoter required for histone modifications in the human β-globin chromatin domain
Debrand, E., Chakalova, L., Miles, J., Dai, Y.-F., Goyenechea, B., Dye, S., Osborne, C., Harju-Baker, S., Pink, R., Caley, D., Carter, D., Peterson, K. R., Fraser, P.
10.1101/639807 — Posted: 2019-05-15
Functional effects of variation in transcription factor binding highlight long-range gene regulation by epromoters
Mitchelmore, J., Grinberg, N., Wallace, C., Spivakov, M.
10.1101/620062 — Posted: 2019-04-29
Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signaling
Durrant, C. S., Ruscher, K., Sheppard, O., Coleman, M. P., Özen, I.
10.1101/585489 — Posted: 2019-03-21
Screening for genes that accelerate the epigenetic ageing clock in humans reveals a role for the H3K36 methyltransferase NSD1
Martin-Herranz, D. E., Aref-Eshghi, E., Bonder, M. J., Stubbs, T. M., Stegle, O., Sadikovic, B., Reik, W., Thornton, J. M.
10.1101/545830 — Posted: 2019-02-10
Chicdiff: a computational pipeline for detecting differential chromosomal interactions in Capture Hi-C data
Cairns, J., Orchard, W. R., Malysheva, V., Spivakov, M.
10.1101/526269 — Posted: 2019-01-22
Single cell multi-omics profiling reveals a hierarchical epigenetic landscape during mammalian germ layer specification
Argelaguet, R., Mohammed, H., Clark, S., Stapel, C., Krueger, C., Kapourani, C. A., Xiang, Y., Hanna, C., Smallwood, S., Ibarra Soria, X., Buettner, F., Sanguinetti, G., Krueger, F., Xie, W., Rugg-Gunn, P., Kelsey, G., Dean, W., Nichols, J., Stegle, O., Marioni, J. C., Reik, W.
10.1101/519207 — Posted: 2019-01-13
Microglia-dependent presynaptic disruption in an organotypic hippocampal slice culture model of neuroinflammation
Sheppard, O., Coleman, M. P., Durrant, C. S.
10.1101/502559 — Posted: 2018-12-20
Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in muscle stem cells
Hernando-Herraez, I., Evano, B., Stubbs, T., Commere, P.-H., Clark, S., Andrews, S., Tajbakhsh, S., Reik, W.
10.1101/500900 — Posted: 2018-12-19

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