Channel:  Babraham Institute

157 Articles

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Single cell multi-omics profiling reveals a hierarchical epigenetic landscape during mammalian germ layer specification
Argelaguet, R., Mohammed, H., Clark, S., Stapel, C., Krueger, C., Kapourani, C. A., Xiang, Y., Hanna, C., Smallwood, S., Ibarra Soria, X., Buettner, F., Sanguinetti, G., Krueger, F., Xie, W., Rugg-Gunn, P., Kelsey, G., Dean, W., Nichols, J., Stegle, O., Marioni, J. C., Reik, W.
10.1101/519207 — Posted: 2019-01-13
Microglia-dependent presynaptic disruption in an organotypic hippocampal slice culture model of neuroinflammation
Sheppard, O., Coleman, M. P., Durrant, C. S.
10.1101/502559 — Posted: 2018-12-20
Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in muscle stem cells
Hernando-Herraez, I., Evano, B., Stubbs, T., Commere, P.-H., Clark, S., Andrews, S., Tajbakhsh, S., Reik, W.
10.1101/500900 — Posted: 2018-12-19
Dppa2 and Dppa4 directly regulate the Dux driven zygotic transcriptional programme
Eckersley-Maslin, M. A., Alda-Catalinas, C., Blotenburg, M., Kreibich, E., Krueger, C., Reik, W.
10.1101/431890 — Posted: 2018-10-01
Genome-scale oscillations in DNA methylation during exit from pluripotency
Rulands, S., Lee, H. J., Clark, S. J., Angermueller, C., Smallwood, S. A., Krueger, F., Mohammed, H., Dean, W., Nichols, J., Rugg-Gunn, P., Kelsey, G., Stegle, O., Simons, B. D., Reik, W.
10.1101/338822 — Posted: 2018-06-05
PI3Kδ hyper-activation promotes the development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner
Stark, A.-K., Chandra, A., Chakraborty, K., Alam, R., Carbonaro, V., Clark, J., Sriskantharajah, S., Bradley, G., Richter, A. G., Banham-Hall, E., Clatworthy, M. R., Nejentsev, S., Hamblin, J. N., Hessel, E. M., Condliffe, A. M., Okkenhaug, K.
10.1101/280651 — Posted: 2018-03-18
Nucleosome remodelling at origins of Global Genome-Nucleotide Excision Repair occurs at the boundaries of higher-order chromatin structure
van Eijk, P., Nandi, S. P., Yu, S., Bennett, M., Leadbitter, M., Teng, Y., Reed, S.
10.1101/283747 — Posted: 2018-03-16
Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data
Olova, N. N., Krueger, F., Andrews, S., Oxley, D., Berrens, R. V., Branco, M. R., Reik, W.
10.1101/165449 — Posted: 2018-03-02
scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells
Clark, S. J., Argelaguet, R., Kapourani, C.-A., Stubbs, T. M., Lee, H. J., Alda-Catalinas, C., Krueger, F., Sanguinetti, G., Kelsey, G., Marioni, J. C., Stegle, O., Reik, W.
10.1101/138685 — Posted: 2018-01-17
Tri-methylation of Histone H3 Lysine 4 Facilitates Gene Expression in Ageing Cells
Cruz, C., Della Rosa, M., Krueger, C., Gao, Q., Field, L., Houseley, J.
10.1101/238048 — Posted: 2017-12-22

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