Channel:  International Mouse Phenotyping Consortium (IMPC)

96 Articles

Genes adapt to outsmart gene targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation
Hosur, V., Low, B. E., Li, D., Stafford, G. A., Kohar, V., Shultz, L. D., Wiles, M. V.
10.1101/2020.04.22.041087 — Posted: 2020-04-24
Desert Hedgehog-driven endothelium integrity is enhanced by Gas1 but negatively regulated by Cdon
Chapouly, C., Hollier, P.-L., Guimbal, S., Cornuault, L., Gadeau, A.-P., Renault, M.-A.
10.1101/2020.04.20.050542 — Posted: 2020-04-20
Whole genome sequencing analysis of the cardiometabolic proteome
Gilly, A. L., Park, Y.-C., Png, G., Barysenka, A., Fischer, I., Bjornland, T., Southam, L., Suveges, D., Neumeyer, S., Rayner, N. W., Tsafantakis, E., Karaleftheri, M., Dedoussis, G., Zeggini, E.
10.1101/854752 — Posted: 2020-04-07
Neuroanatomy and Behaviour in Mice with a Haploinsufficiency of AT-Rich Interactive Domain 1B (ARID1B) Throughout Development
Ellegood, J., Petkova, S. P., Kinman, A., Qiu, L. R., Wade, A. A., Fernandes, D. J., Lindenmaier, Z., Creighton, A., Nutter, L., Nord, A. S., Silverman, J. L., Lerch, J. P.
10.1101/2020.03.31.017905 — Posted: 2020-04-01
The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis
Carrat, G. R., Haythorne, E., Tomas, A., Haataja, L., Mueller, A., Arvan, P., Piunti, A., Cheng, K., Huang, M., Pullen, T., Georgiadou, E., Stylianides, T., Amirruddin, N. S., Salem, V., Distaso, W., Cakebread, A., Heesom, K. J., Lewis, P. A., Hodson, D., Briant, L. J., Fung, A. C. H., Sessions, R. B., Alpy, F., Kong, A. P. S., Benke, P. I., Torta, F., Teo, A. K. K., Leclerc, I., Solimena, M., Wigley, D. B., Rutter, G. A.
10.1101/2020.03.25.007286 — Posted: 2020-03-26
Functional modeling of NMIHBA-causing PRUNE1 variants reveals a requirement for its exopolyphosphatase activity.
Nistala, H., Dronzek, J., Gonzaga-Jauregui, C., Man Chim, S., Rajamani, S., Nuwayhid, S., Delgado, D., Burke, E., Karaca, E., Franklin, M. C., Sarangapani, P., Podgorski, M., Tang, Y., Dominguez, M. G., Withers, M., Deckelbaum, R. A., Scheonherr, C. J., Gahl, W. A., Malicdan, M. C., Zambrowicz, B., Gale, N. W., Gibbs, R. A., Chung, W. K., Lupski, J. R., Economides, A. N.
10.1101/2020.03.02.973909 — Posted: 2020-03-26
Mutant screen for reproduction unveils depression-associated Piccolo's control over reproductive behavior
A. Medrano, G., Singh, M., J. Plautz, E., B. Good, L., M. Chapman, K., Chaudhary, J., Jaichander, P., M. Powell, H., Pudasaini, A., M. Shelton, J., A. Richardson, J., Xie, X.-J., Ivics, Z., Braun, C., Ackermann, F., C. Garner, C., Izsvak, Z., Hamra, F. K.
10.1101/405985 — Posted: 2020-03-19
Genetic disruption of the Blood Brain Barrier leads to protective barrier formation at the Glia Limitans
Hollier, P. L., Guimbal, S., Mora, P., Diop, A., Cornuault, L., Couffinhal, T., Gadeau, A. P., Renault, M.-A., Chapouly, C.
10.1101/2020.03.13.990762 — Posted: 2020-03-15
Endothelial cell response to Hedgehog ligands depends on their processing
Hollier, P.-L., Chapouly, C., Diop, A., Guimbal, S., Cornuault, L., Gadeau, A.-P., Renault, M.-A.
10.1101/2020.03.03.974444 — Posted: 2020-03-03
Coordination of asparagine uptake and asparagine synthetase expression is required for T cell activation
Hope, H. C., Brownlie, R. J., Steele, L., Salmond, R. J.
10.1101/2020.02.28.969774 — Posted: 2020-03-01

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