COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,901 Articles (22,568 medRxiv, 8,333 bioRxiv)

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Identification of inhibitors of SARS-CoV-2 3CL-Pro enzymatic activity using a small molecule in-vitro repurposing screen
Kuzikov, M., Costanzi, E., Reinshagen, J., Esposito, F., Vangeel, L., Wolf, M., Ellinger, B., Claussen, C., Geisslinger, G., Corona, A., Iaconis, D., Talarico, C., Manelfi, C., Cannalire, R., Rossetti, G., Gossen, J., Albani, S., Musiani, F., Herzog, K., Ye, Y., Giabbai, B., Demitri, N., Jochmans, D., De Jonghe, S., Rymenants, J., Summa, V., Tramontano, E., Beccari, A. R., Leyssen, P., Storici, P., Neyts, J., Gribbon, P., Zaliani, A.
10.1101/2020.12.16.422677 — Posted: 2020-12-16
Choice of assemblers has a critical impact on de novo assembly of SARS-CoV-2 genome and characterizing variants
Islam, R., Raju, R. S., Tasnim, N., Shihab, M. I. H., Bhuiyan, M. A., Araf, Y., Islam, T.
10.1101/2020.12.15.422939 — Posted: 2020-12-16
Cyclic gallium-68 labeled peptides for specific detection of human angiotensin-converting enzyme 2
Parker, M., Blecha, J., Rosenberg, O., Ohliger, M., Flavell, R., Wilson, D. M.
10.1101/2020.12.15.412809 — Posted: 2020-12-16
Remdesivir is a delayed translocation inhibitor of SARS CoV-2 replication in vitro
Bravo, J. P., Dangerfield, T. L., Taylor, D. W., Johnson, K. A.
10.1101/2020.12.14.422718 — Posted: 2020-12-16
Characteristics and Risk Factors for Hospitalization and Mortality among Persons with COVID-19 in Atlanta Metropolitan Area
Chishinga, N., Gandhi, N. R., Onwubiko, U. N., Telford, C., Prieto, J., Smith, S., Chamberlain, A. T., Khan, S., Williams, S., Khan, F., Shah, S.
10.1101/2020.12.15.20248214 — Posted: 2020-12-16
Shared genetic etiology between idiopathic pulmonary fibrosis and COVID-19 severity
Fadista, J., Kraven, L. M., Karjalainen, J., Andrews, S. J., Geller, F., The COVID-19 Host Genetics Initiative, , Baillie, J. K., Wain, L. V., Gisli Jenkins, R., Feenstra, B.
10.1101/2020.12.15.20248279 — Posted: 2020-12-16
Predicting the need for escalation of care or death from repeated daily clinical observations and laboratory results in patients with SARS-CoV-2 during 2020: a retrospective population-based cohort study from the United Kingdom
Crooks, C. J., West, J., Fogarty, A., Morling, J. R., Grainge, M. J., Gonem, S., Simmonds, M., Race, A., Juurlink, I., Briggs, S., Cruikshank, S., Hammond-Pears, S., Card, T. R.
10.1101/2020.12.14.20248181 — Posted: 2020-12-16
Diagnostic accuracy of Loop mediated isothermal amplification coupled to Nanopore sequencing for the detection of SARS-CoV-2 infection at scale in symptomatic and asymptomatic populations
Ptasinska, A., Whalley, C., Bosworth, A., Poxon, C., Bryer, C., Grippon, S., Wise, E., Armson, B., Goring, A., Cortes, N. J., Howson, E., Snell, G., Forster, J., Mattocks, C., Frampton, S., Anderson, R., Cleary, D., Parker, J., Boukas, K., Graham, N., Cellura, D., Garratt, E., Skilton, R., Sheldon, H., Collins, A., Ahmad, N., Friar, S., Godfrey, K., Williams, T., Deans, S., Douglas, A., Hill, S. L., Kidd, M., Porter, D., Kidd, S. P., Fowler, V., Williams, T., Richter, A. G., Beggs, A. D.
10.1101/2020.12.15.20247031 — Posted: 2020-12-16 Discussion: Onsite
Development of a Rapid Point-Of-Care Test that Measures Neutralizing Antibodies to SARS-CoV-2
Lake, D. F., Roeder, A. J., Kaleta, E., Jasbi, P., Periasamy, S., Kuzmina, N., Bukreyev, A., Grys, T. E., Wu, L., Mills, J. R., McAulay, K., Seit-Nebi, A., Svarovsky, S.
10.1101/2020.12.15.20248264 — Posted: 2020-12-16
Common genetic variants identify therapeutic targets for COVID-19 and individuals at high risk of severe disease
Horowitz, J. E., Kosmicki, J. A., Damask, A., Sharma, D., Roberts, G. H. L., Justice, A. A. E., Banerjee, N., Coignet, M. V., Yadav, A., Leader, J. B., Marcketta, A., Park, D. S., Lanche, R., Maxwell, E., Knight, S. C., Bai, X., Guturu, H., Sun, D., Baltzell, A., Kury, F. S. P., Backman, J. D., Girshick, A. R., O'Dushlaine, C., McCurdy, S. R., Partha, R., Mansfield, A. J., Turissini, D. A., Li, A. H., Zhang, M., Mbatchou, J., Watanabe, K., Gurski, L., McCarthy, S. E., Verma, A., Sirugo, G., Regeneron Genetics Center, , Ritchie, M. D., Jones, M., Balasubramanian, S., Salerno, W. J., Shuldiner, A. R., Rader, D. J., Mirshahi, T., Locke, A. E., Marchini, J., Overton, J. D., Carey, D. J., Habegger, L., Cantor, M. N., Rand, K. A., Hong, E. L., Reid, J. G., Ball, C. A., Baras, A., Abecasis, G. R., Ferreira, M. A.
10.1101/2020.12.14.20248176 — Posted: 2020-12-16

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).