COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,643 Articles (22,459 medRxiv, 8,184 bioRxiv)

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Structure-based design of a highly stable, covalently-linked SARS-CoV-2 spike trimer with improved structural properties and immunogenicity
Olmedillas, E., Mann, C. J., Peng, W., Wang, Y.-T., Diaz Avalos, R., Bedinger, D., Valentine, K., Shafee, N., Schendel, S. L., Yuan, M., Lang, G., Rouet, R., Christ, D., Jiang, W., Wilson, I. A., Germann, T., Shresta, S., Snijder, J., Ollmann Saphire, E.
10.1101/2021.05.06.441046 — Posted: 2021-05-06
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells
Mahoney, M., Damalanka, V. C., Tartell, M., Chung, D. H., Lourenco, A. L., Pwee, D., Mayer Bridwell, A. E., Hoffmann, M., Voss, J., Karmakar, P., Azouz, N. P., Klinger, A. M., Rothlauf, P. W., Thompson, C. E., Lee, M., Klampfer, L., Stallings, C., Rothenberg, M. E., Pöhlmann, S., Whelan, S. P. J., O'Donoghue, A. J., Craik, C. S., Janetka, J. W.
10.1101/2021.05.06.442935 — Posted: 2021-05-06
Diversity and selection of SARS-CoV-2 minority variants in the early New York City outbreak
Roder, A., Khalfan, M., Johnson, K. E., Ruchnewitz, D., Knoll, M., Banakis, S., Wang, W., Samanovic, M. I., Mulligan, M. J., Gresham, D., Laessig, M., Luksza, M., Ghedin, E.
10.1101/2021.05.05.442873 — Posted: 2021-05-06
The Effect of Minnelide against SARS-CoV-2 in a Murine Model
Caballero Van Dyke, M. C., Mead, H. L., Bryant, M., Laux, K. L., Kollath, D. R., Coyne, V. K., Miller, K. J., Stone, N. E., Jaramillo, S. A., Keim, P., Milikowski, C., Gupta, V. K., Vickers, S. M., Saluja, A., Velagapudi, M. R., Barker, B. M.
10.1101/2021.05.05.442875 — Posted: 2021-05-06
Identification of DAXX As A Restriction Factor Of SARS-CoV-2 Through A CRISPR/Cas9 Screen
Mac Kain, A., Maarifi, G., Aicher, S.-M., Arhel, N., Baidaliuk, A., Vallet, T., Tran, Q. D., Hardy, A., Chazal, M., Porrot, F., Ohainle, M., Carlson-Stevermer, J., Oki, J., Holden, K., Simon-Loriere, E., Bruel, T., Schwartz, O., Jouvenet, N., Nisole, S., Vignuzzi, M., Roesch, F.
10.1101/2021.05.06.442916 — Posted: 2021-05-06
Development of Potent and Effective Synthetic SARS-CoV-2 Neutralizing Nanobodies
Stefan, M. A., Light, Y. K., Schwedler, J. L., McIlroy, P. R., Courtney, C. M., Saada, E. A., Thatcher, C. E., Phillips, A. M., Bourguet, F. A., Mageeney, C. M., McCloy, S. A., Collette, N. M., Negrete, O. A., Schoeniger, J. S., Weilhammer, D. R., Harmon, B.
10.1101/2021.05.06.442911 — Posted: 2021-05-06
SARS-CoV-2 seroprevalence in Germany - a population based sequential study in five regions
Gornyk, D., Harries, M., Gloeckner, S., Strengert, M., Kerrinnes, T., Bojara, G., Castell, S., Frank, K., Gubbe, K., Heise, J.-K., Hernandez, P., Kappert, O., Kern, W., Illig, T., Klopp, N., Maass, H., Ortmann, J., Kessel, B., Roller, G., Schlueter, M., Tonn, T., Ziemons, M., Kemmling, Y., Lange, B., Krause, G.
10.1101/2021.05.04.21256597 — Posted: 2021-05-06
SARS-CoV-2 infection and reinfection in a seroepidemiological workplace cohort in the United States
Finch, E., Lowe, R., Fischinger, S., de St Aubin, M., Siddiqui, S. M., Dayal, D., Loesche, M. A., Rhee, J., Berger, S., Hu, Y., Gluck, M. J., Mormann, B., Hasdianda, M. A., Musk, E. R., Alter, G., Menon, A. S., Nilles, E. J., Kucharski, A. J.
10.1101/2021.05.04.21256609 — Posted: 2021-05-06
Derivation and external validation of a simple risk score to predict in-hospital mortality in patients hospitalized for COVID-19
Mann, C. Z., Abshire, C., Yost, M., Kaatz, S., Swaminathan, L., Flanders, S. A., Prescott, H. C., Gagnon-Bartsch, J. A.
10.1101/2021.05.04.21256599 — Posted: 2021-05-06
Obstructive sleep apnea is highly prevalent in COVID19 moderate to severe ARDS survivors: Findings of level I Polysomnography in a tertiary care hospital
Goyal, A., Saxena, K., Kar, A., Khurana, A., Pakhare, A. P., Bhagtana, P. K., Sridevi, C. S. K. R.
10.1101/2021.05.04.21256593 — Posted: 2021-05-06

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).