COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,788 Articles (22,946 medRxiv, 8,842 bioRxiv)

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Infection of 5xFAD mice with a mouse-adapted SARS-CoV-2 does not alter Alzheimer's disease neuropathology yet induces wide-spread changes in gene expression across diverse cell types
Furman, S., Zayou, L., Tsourmas, K. I. I., Javonillo, D. I., Olivarria, G. M., Cheng, Y., Pachow, C., Fernandez, K., Le, L., Edwards, R. A., Nicholas, D., Sanchez, G. P., Baric, R. S., Green, K. N., Lane, T. E.
10.64898/2025.12.19.695600 — Posted: 2025-12-22
Including gender-specific features in epidemic modeling: the case of the second wave of COVID-19 in Italy
De Gaetano, A., Coletti, P., Perra, N., Barrat, A., Paolotti, D.
10.64898/2025.12.19.25342675 — Posted: 2025-12-21
Evidence of Accumulating Neurophysiologic Dysfunction in Persistent Post-COVID Fatigue
Germann, M., Maffitt, N. J., Burton, O. A., Ashhad, A., Baker, A. M. E., Zaaimi, B., Ng, W.-F., Soteropoulos, D. S., Baker, S. N., Baker, M. R.
10.64898/2025.12.19.25342669 — Posted: 2025-12-21
Identification and genomic characterisation of BA.3.2: a highly divergent BA.3-related SARS-CoV-2 lineage from southern Africa
Dor, G., Kekana, D., Hisner, R., Martin, D. P., Korber, B., Gueli, F., Ernst, T., Levy, A., Speers, D., Turville, S., Sintchenko, V., Basile, K., Sullivan, G., Rockett, R., Kok, J., Lessels, R., Wolter, N., von Gottberg, A., Tegally, H., de Oliveira, T.
10.64898/2025.12.19.25342658 — Posted: 2025-12-20
An Oral Combination therapy against SARS-CoV-2 based on Synergistic Action of Auranofin and Remdesivir.
Khatun, O., Narayan, R., Nagaraj, S. K., Shiraz, R., Kaliappan, A., Kaur, S., Singh, A., Narayanan, S., Shandil, R., Tomar, S., Tripathi, S.
10.64898/2025.12.19.695342 — Posted: 2025-12-19
The pharmacokinetics, bio-distribution and therapeutic efficacy of a trimeric nanobody against SARS-CoV-2 in the Syrian golden hamster COVID-19 model
Sharma, P., Mega, D., Kirby, A., Buckle, I., Kipar, A., Clark, J., Bentley, E., Eyssen, L., Kijak, E., Herriott, J., Sharp, J., Carroll, M. W., Owens, R., Stewart, J. P.
10.64898/2025.12.17.694727 — Posted: 2025-12-19
IGHV3-53 antibody abundance drives divergent SARS-CoV-2 immune imprinting
Niu, X., Jian, F., Li, Y., Li, K., Lei, S., Song, W., Kong, R., Cai, X., An, R., Wang, Y., Huang, Y., Yu, L., Wang, W., Sun, H., Yu, Y., Wang, J., Zhang, B., Zhu, T., Huang, J., Shao, F., Luo, S., Tan, X., Cao, Y.
10.64898/2025.12.18.694353 — Posted: 2025-12-19
Single-Particle Tracking and Positional Phenotyping Reveals Variant-Specific Early Checkpoints in SARS-CoV-2 Cell Entry
Schulz, F. H., Dreisler, M. W., Koylyu, D., Valero, J., Malle, M. G., Civit, L., Kjems, J., Hatzakis, N. S.
10.64898/2025.12.18.695048 — Posted: 2025-12-19
Patient needs and expectations regarding cognitive impairments in long COVID: perspectives of young and older adults in the UK
UK Long COVID Cognitive Experience Research Group, , Shan, D.
10.64898/2025.12.17.25342465 — Posted: 2025-12-18
Collective interactions, human mobility and viral evolution shaped the SARS-CoV-2 transmission in Mainland China
Wang, D., Wang, Y., Gressani, O., Chen, J., Tao, Y., Wang, H., Li, S., Chen, D., H. Y. Lau, E., Zhao, Y., Wu, P., Zhang, Q., Cowling, B. J., Ali, S. T.
10.64898/2025.12.17.25342513 — Posted: 2025-12-18

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Subject Areas
* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).