COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,607 Articles (22,913 medRxiv, 8,694 bioRxiv)

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Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
Ma, C., Hurst, B., Hu, Y., Szeto, T., Tarbet, B., Wang, J.
10.1101/2020.04.20.051581 — Posted: 2020-04-20 Discussion: Onsite
Protocol and reagents for pseudotyping lentiviral particles with SARS-CoV-2 Spike protein for neutralization assays
Crawford, K. H. D., Eguia, R., Dingens, A. S., Loes, A. N., Malone, K. D., Wolf, C. R., Chu, H. Y., Tortorici, M. A., Veesler, D., Murphy, M., Pettie, D., King, N. P., Balazs, A. B., Bloom, J. D.
10.1101/2020.04.20.051219 — Posted: 2020-04-20 Discussion: Onsite
Design an efficient multi-epitope peptide vaccine candidate against SARS-CoV-2: An in silico analysis
Yazdani, Z., Rafiei, A., Yazdani, M., Valadan, R.
10.1101/2020.04.20.051557 — Posted: 2020-04-20
Phylodynamics of SARS-CoV-2 transmission in Spain
Diez Fuertes, F., Iglesias Caballero, M., Monzon, S., Jimenez, P., Varona, S., Cuesta, I., Zaballos, A., Thomson, M. M., Jimenez, M., Garcia Perez, J., Pozo, F., Perez Olmeda, M., Alcami, J., Casas, I.
10.1101/2020.04.20.050039 — Posted: 2020-04-20
Limited SARS-CoV-2 diversity within hosts and following passage in cell culture
Moreno, G. K., Braun, K. M., Halfmann, P. J., Prall, T. M., Riemersma, K. K., Haj, A. K., Lalli, J., Florek, K. R., Friedrich, T. C., Kawaoka, Y., O'Connor, D. H.
10.1101/2020.04.20.051011 — Posted: 2020-04-20
Exceptional diversity and selection pressure on SARS-CoV and SARS-CoV-2 host receptor in bats compared to other mammals
Frank, H. K., Enard, D., Boyd, S. D.
10.1101/2020.04.20.051656 — Posted: 2020-04-20
Blocking antibodies against SARS-CoV-2 RBD isolated from a phage display antibody library using a competitive biopanning strategy
Zeng, X., Li, L., Lin, J., Li, X., Liu, B., Kong, Y., Zeng, S., Du, J., Xiao, H., Zhang, T., Zhang, S., Liu, J.
10.1101/2020.04.19.049643 — Posted: 2020-04-20
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
Ogando, N., Dalebout, T., Zevenhoven-Dobbe, J. C., Limpens, R. W. A. L., van der Meer, Y., Caly, L., Druce, J., de Vries, J., Kikkert, M., Barcena, M., Sidorov, I., Snijder, E. J.
10.1101/2020.04.20.049924 — Posted: 2020-04-20 Discussion: Offsite
Leverging Deep Learning to Simulate Coronavirus Spike proteins has the potential to predict future Zoonotic sequences
Crossman, L. C.
10.1101/2020.04.20.046920 — Posted: 2020-04-20
Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells
Muus, C., Luecken, M. D., Eraslan, G., Waghray, A., Heimberg, G., Sikkema, L., Kobayashi, Y., Vaishnav, E. D., Subramanian, A., Smilie, C., Jagadeesh, K., Duong, E. T., Fiskin, E., Triglia, E. T., Ansari, M., Cai, P., Lin, B., Buchanan, J., Chen, S., Shu, J., Haber, A. L., Chung, H., Montoro, D. T., Adams, T., Aliee, H., Samuel, J., Andrusivova, A. Z., Angelidis, I., Ashenberg, O., Bassler, K., Bécavin, C., Benhar, I., Bergenstråhle, J., Bergenstråhle, L., Bolt, L., Braun, E., Bui, L. T., Chaffin, M., Chichelnitskiy, E., Chiou, J., Conlon, T. M., Cuoco, M. S., Deprez, M., Fischer, D. S., Gillich, A., Gould, J., Guo, M., Gutierrez, A. J., Habermann, A. C., Harvey, T., He, P., Hou, X., Hu, L., Jaiswal, A., Jiang, P., Kapellos, T., Kuo, C. S., Larsson, L., Leney-Greene, M. A., Lim, K., Litviňuková, M., Lu, J., Ludwig, L. S., Luo, W., Maatz, H., Madissoon, E., Mamanova, L., Manakongtreecheep, K., Marquette, C., Mbano, I., McAdams, A. M., Metzger, R. J., Nabhan, A. N., Nyquist, S. K., Penland, L., Poirion, O. B., Poli, S., Qi, C., Queen, R., Reichart, D., Rosas, I., Schupp, J., Sinha, R., Sit, R. V., Slowikowski, K., Slyper, M., Smith, N., Sountoulidis, A., Strunz, M., Sun, D., Talavera-López, C., Tan, P., Tantivit, J., Travaglini, K. J., Tucker, N. R., Vernon, K., Wadsworth, M. H., Waldman, J., Wang, X., Yan, W., Zhao, W., Ziegler, C. G., The NHLBI LungMAP Consortium, The Human Cell Atlas Lung Biological Network
10.1101/2020.04.19.049254 — Posted: 2020-04-20 Discussion: Onsite | Offsite

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).