COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,617 Articles (22,913 medRxiv, 8,704 bioRxiv)

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Rethinking Remdesivir: Synthesis of Lipid Prodrugs that Substantially Enhance Anti-Coronavirus Activity
Schooley, R. T., Carlin, A. F., Beadle, J. R., Valiaeva, N., Zhang, X.-Q., Garretson, A. F., Smith, V. I., Murphy, J. A., Hostetler, K. Y.
10.1101/2020.08.26.269159 — Posted: 2020-08-27
The immunodominant and neutralization linear epitopes for SARS-CoV-2
Lu, S., Xie, X.-x., Zhao, L., Wang, B., Zhu, J., Yang, T.-r., Yang, G.-w., Ji, M., Lv, C.-p., Xue, J., Dai, E.-h., Fu, X.-m., Liu, D.-q., Zhang, L., Hou, S.-j., Yu, X.-l., Wang, Y.-l., Gao, H.-x., Shi, X.-h., Ke, C.-w., Ke, B.-x., Jiang, C.-g., Liu, R.-t.
10.1101/2020.08.27.267716 — Posted: 2020-08-27 Discussion: Offsite
Serum Amyloid P inhibits single stranded RNA-induced lung inflammation, lung damage, and cytokine storm in mice
Karhadkar, T. R., Pilling, D., Gomer, R. H.
10.1101/2020.08.26.269183 — Posted: 2020-08-27
SARS-CoV-2 genomic and quasispecies analyses in cancer patients reveal relaxed intrahost virus evolution
Siqueira, J., Goes, L. R., Alves, B. M., de Carvalho, P. S., Cicala, C., Arthos, J., Viola, J. P. B., de Melo, A. C., Soares, M. A., INCA COVID-19 Task Force (names of participants listed in the acknowledgements section number of cha
10.1101/2020.08.26.267831 — Posted: 2020-08-26 Discussion: Onsite
Risk factors for outbreaks of COVID-19 in care homes following hospital discharge: a national cohort analysis
Emmerson, C., Adamson, J. P., Turner, D., Gravenor, M. B., Salmon, J., Cottrell, S., Middleton, V., Thomas, B., Mason, B., Williams, C. J.
10.1101/2020.08.24.20168955 — Posted: 2020-08-26 Discussion: Onsite
Molecular dynamics reveals complex compensatory effects of ionic strength on the SARS-CoV-2 Spike/hACE-2 interaction
Souza, A. S. d., Rivera, J. D., Medeiros, V., Ge, P., Souza, R. F. d., Farah, C. S., Ulrich, H., Marana, S. R., Kopke Salinas, R., Guzzo, C. R.
10.1101/2020.08.25.267351 — Posted: 2020-08-26
Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis
Johnson, B. A., Xie, X., Kalveram, B., Lokugamage, K. G., Muruato, A., Zou, J., Zhang, X., Juelich, T., Smith, J. K., Zhang, L., Schindewolf, C., Vu, M. N., Vanderheiden, A., Plante, J. A., Plante, K. S., Lee, B., Weaver, S., Suthar, M., Routh, A. L., Ren, P. L., Ku, Z., An, Z., Debbink, K., Shi, P. Y., Freiberg, A. N., Menachery, V. D.
10.1101/2020.08.26.268854 — Posted: 2020-08-26 Discussion: Onsite | Offsite
The SARS-CoV-2 Spike mutation D614G increases entry fitness across a range of ACE2 levels, directly outcompetes the wild type, and is preferentially incorporated into trimers
Michaud, W. A., Boland, G. M., Rabi, S. A.
10.1101/2020.08.25.267500 — Posted: 2020-08-26 Discussion: Onsite
Epitopes targeted by T cells in convalescent COVID-19 patients
Quadeer, A. A., Ahmed, S. F., McKay, M. R.
10.1101/2020.08.26.267724 — Posted: 2020-08-26
AI aided design of epitope-based vaccine for the induction of cellular immune responses against SARS-CoV-2
Mazzocco, G., Niemiec, I., Myronov, A., Skoczylas, P., Kaczmarczyk, J., Sanecka-Duin, A., Gruba, K., Krol, P., Drwal, M., Szczepanik, M., Pyrc, K., Stepniak, P.
10.1101/2020.08.26.267997 — Posted: 2020-08-26

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).