COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,823 Articles (22,968 medRxiv, 8,855 bioRxiv)

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The Dual-Antigen Ad5 COVID-19 Vaccine Delivered as an Intranasal Plus Subcutaneous Prime Elicits Th1 Dominant T-Cell and Humoral Responses in CD-1 Mice
Rice, A., Verma, M., Shin, A., Zakin, L., Sieling, P., Tanaka, S., Balint, J., Dinkins, K., Adisetiyo, H., Morimoto, B., Taft, J., Patel, R. S., Buta, S., Martin-Fernandez, M., Bogunovic, D., Spilman, P. R., Gabitzsch, E. R., Safrit, J. T., Rabizadeh, S., Niazi, K., Soon-Shiong, P.
10.1101/2021.03.22.436476 — Posted: 2021-03-23
Protein-primed RNA synthesis in SARS-CoVs and structural basis for inhibition by AT-527
Shannon, A., Fattorini, V., Sama, B., Selisko, B., Feracci, M., Falcou, C., Gauffre, P., El Kazzi, P., Decroly, E., Rabah, N., Toulon, K., Eydoux, C., Guillemot, J.-C., Noel, M., Debart, F., Vasseur, J.-J., Moussa, A., Good, S., Lin, K., Sommadossi, J.-P., Zhu, Y., Yan, X., Shi, H., Ferron, F., Canard, B.
10.1101/2021.03.23.436564 — Posted: 2021-03-23
Emergence of the E484K Mutation in SARS-CoV-2 Lineage B.1.1.220 in Upstate New York
Lesho, E., Corey, B., Lebreton, F., Ong, A., Swierczewski, B., Bennett, J., Walsh, E., McGann, P.
10.1101/2021.03.11.21253231 — Posted: 2021-03-23 Discussion: Offsite
The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection
Sandoval, D. R., Mandel Clausen, T., Nora, C., Magida, J. A., Cribbs, A. P., Denardo, A., Clark, A. E., Garretson, A. F., Coker, J. K. C., Narayanan, A., Majowicz, S. A., Philpott, M., Johansson, C., Dunford, J. E., Spliid, C. B., Golden, G. J., Payne, N. C., Tye, M. A., Nowell, C. J., Griffis, E. R., Piermatteo, A., Grunddal, K. V., Alle, T., Hauser, B. M., Feldman, J., Caradonna, T. M., Pu, Y., Yin, X., McVicar, R. N., Kwong, E. M., Tsimikas, S., Schmidt, A. G., Ballatore, C., Zengler, K., Chanda, S. K., Weiss, R. J., Downes, M., Evans, R. M., Croker, B. A., Leibel, S. L., Jose, J., Mazitschek, R., Oppermann, U., Esko, J. D., Carlin, A. F., Gordts, P. L. S. M.
10.1101/2021.03.22.436522 — Posted: 2021-03-23
Antidepressant and antipsychotic drugs reduce viral infection by SARS-CoV-2 and fluoxetine show antiviral activity against the novel variants in vitro
Fred, M. S., Kuivanen, S., Ugurlu, H., Cabrera Casarotto, P., Levanov, L., Saksela, K., Vapalahti, O., Castren, E.
10.1101/2021.03.22.436379 — Posted: 2021-03-23
Age-related changes in the upper respiratory microbiome are associated with SARS-CoV-2 susceptibility and illness severity
Hurst, J. H., McCumber, A. W., Aquino, J. N., Rodriguez, J., Heston, S. M., Lugo, D. J., Rotta, A. T., Turner, N. A., Pfeiffer, T. S., Gurley, T. C., Moody, M. A., Denny, T. N., Rawls, J. F., Woods, C. W., Kelly, M. S.
10.1101/2021.03.20.21252680 — Posted: 2021-03-23
Detection of Mutations Associated with Variants of Concern Via High Throughput Sequencing of SARS-CoV-2 Isolated from NYC Wastewater
Smyth, D. S., Trujillo, M., Cheung, K., Gao, A., Hoxie, I., Kannoly, S., Kubota, N., Markman, M., San, K., Sompanya, G., Dennehy, J. J.
10.1101/2021.03.21.21253978 — Posted: 2021-03-23
Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol.
Sigfrid, L., Drake, T. M., Pauley, E., Jesudason, E. C., Olliaro, P., Lim, W. S., Gillesen, A., Berry, C., Lowe, D., McPeake, J., Lone, N., Munblit, D., Casey, A., Bannister, P., Russell, C. D., Goodwin, L., Ho, A., Turtle, L., Hara, M. O., Hastie, C., Donohue, C., Spencer, R., Donegan, C., Gummery, A., Harrison, J., Hardwick, H., Hastie, C. E., Carson, G., Merson, L., Baillie, J. K., Openshaw, P., Harrison, E. M., Docherty, A., Semple, M. G., Scott, J. T.
10.1101/2021.03.18.21253888 — Posted: 2021-03-23
In-person schooling and COVID-19 transmission in Canada's three largest cities
Bignami, S., Boujija, Y., Fisman, D., Sandberg, J.
10.1101/2021.03.21.21254064 — Posted: 2021-03-23
Corticosteroids and mortality in patients with severe Covid-19 who have autoantibodies
Cui, Z., Roth, M., Averbukh, Y., Assa, A., Al-ani, A., Southern, W., Reyes Gill, M., Arora, S.
10.1101/2021.03.19.21253005 — Posted: 2021-03-23

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).