COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,252 Articles (22,733 medRxiv, 8,519 bioRxiv)

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Structure and computation-guided design of a mutation-integrated trimeric RBD candidate vaccine with broad neutralization against SARS-CoV-2
Liang, Y., Zhang, J., Yuan, R. Y., Wang, M. Y., He, P., Su, J. G., Han, Z. B., Jin, Y. Q., Hou, J. W., Zhang, H., Zhang, X. F., Shao, S., Hou, Y. N., Liu, Z. M., Du, L. F., Shen, F. J., Zhou, W. M., Tang, F., Lei, Z. H., Liu, S., Zhen, W., Wu, J. J., Zheng, X., Liu, N., Chen, S., Ma, Z. J., Zheng, F., Ren, S. Y., Hu, Z. Y., Wu, G. Z., Huang, W. J., Ke, C. W., Li, Q. M.
10.1101/2021.06.18.448958 — Posted: 2021-06-18
Influence of viral transport media and freeze-thaw cycling on the sensitivity of qRT-PCR detection of SARS-CoV-2 nucleic acids
Holohan, C., Hanrahan, S., Feely, N., Li, P., O'Connell, J., Moss, C., Carr, M. J., Tagit, O., Lee, G. U.
10.1101/2021.06.18.448982 — Posted: 2021-06-18
No evidence of SARS-CoV-2 infection in Neotropical Primates sampled during COVID-19 pandemic in Minas Gerais and Rio Grande do Sul, Brazil.
Abreu, F. V. S. d., Macedo, M. V., Silva, A. J. J. d., Oliveira, C. H. d., Ottone, V. d. O., Almeida, M. A. B. d., Santos, E. d., Cardoso, J. D. C., Campos, A. S., Silva, C. M. D. d., Silva, A. G. d., Andrade, M. d. S., Bernis, V. M. O., Bernis Filho, W. O., Trindade, G. d. S., Albuquerque, G. R., Seva, A. d. P., Ribeiro, B. M., Teixeira, D. S., Campos, F. S., Franco, A. C., Roehe, P. M., Oliveira, D. B. d.
10.1101/2021.06.17.448890 — Posted: 2021-06-18
A novel bivalent DNA vaccine encoding both spike protein receptor-binding domain and nucleocapsid protein of SARS-CoV-2 to elicit T cell and neutralising antibody responses that cross react with variants
Brentville, V. A., Vankemmelbeke, M., Methingham, R. L., Symonds, P., Cook, K. W., Urbanowicz, R. A., Tsoleridis, T., Coleman, C. M., Chang, K.-C., Skinner, A., Dubinina, E., Daniels, I., Shah, S., Dixon, J. E., Pockley, A. G., Adams, S. E., Paston, S. J., Daly, J. M., Ball, J. K., Durrant, L. G.
10.1101/2021.06.18.448932 — Posted: 2021-06-18
Binding of phosphatidylserine-positive microparticles by PBMCs classifies disease severity in COVID-19 patients
Rausch, L., Lutz, K., Schifferer, M., Winheim, E., Gruber, R., Rinke, L., Hellmuth, J., Scheerer, C., Muenchhoff, M., Mandel, C., Bergwelt-Baildon, M., Simons, M., Straub, T., Krug, A. B., Kranich, J., Brocker, T.
10.1101/2021.06.18.448935 — Posted: 2021-06-18
Probing Affinity, Avidity, Anti-Cooperativity, and Competition in Antibody and Receptor Binding to the SARS-CoV-2 Spike by Single Particle Mass Analyses
Yin, V. C., Lai, S.-H., Caniels, T. G., Brouwer, P. J. M., Brinkkemper, M., Aldon, Y., Liu, H., Yuan, M., Wilson, I. A., Sanders, R. W., van Gils, M., Heck, A. J. R.
10.1101/2021.06.18.448939 — Posted: 2021-06-18
Identification of SGLT2 inhibitor Ertugliflozin as a treatment for COVID-19 using computational and experimental paradigm
Saxena, S., Meher, K., Rotella, M., Vangala, S., Chandran, S., Malhotra, N., Palakodeti, R., Voleti, S., Saxena, U.
10.1101/2021.06.18.448921 — Posted: 2021-06-18 Discussion: Offsite
A Robust High-throughput Fluorescent Polarization Assay for the Evaluation and Screening of SARS-CoV-2 Fusion Inhibitors
Yin, X., Chen, L., Yuan, S., Liu, L., Gao, Z.
10.1101/2021.06.17.448891 — Posted: 2021-06-18
Generation and transmission of inter-lineage recombinants in the SARS-CoV-2 pandemic
Jackson, B., Boni, M. F., Bull, M. J., Colleran, A., Colquhoun, R. M., Darby, A., Haldenby, S., Hill, V., Lucaci, A., McCrone, J. T., Nicholls, S., O'Toole, A., Pacchiarini, N., Poplawski, R., Scher, E., Todd, F., Webster, H., Whitehead, M., Wierzbicki, C., The COVID-19 Genomics UK (COG-UK) consortium, , Loman, N. J., Connor, T. R., Robertson, D. L., Pybus, O. L., Rambaut, A.
10.1101/2021.06.18.21258689 — Posted: 2021-06-18 Discussion: Offsite
Survival of vaccine-induced human milk SARS-CoV-2 IgG and IgA immunoglobulins across simulated human infant gastrointestinal digestion
Pieri, M., Nicolaidou, V., Paphiti, I., Pipis, S., Felekkis, K., Papaneophytou, C.
10.1101/2021.06.17.21259021 — Posted: 2021-06-18

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).