COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,696 Articles (22,913 medRxiv, 8,783 bioRxiv)

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The P3 O-Tert-Butyl-Threonine is Key to High Cellular and Antiviral Potency for Aldehyde-Based SARS-CoV-2 Main Protease Inhibitors
Ma, Y., Yang, K., Geng, Z. Z., Alugubellia, Y. R., Shaabani, N., Vatansever, E. C., Ma, X. R., Cho, C.-C., Khatua, K., Blankenship, L., Yu, G., Sankaran, B., Li, P., Allen, R., Ji, H., Xu, S., Liu, W. R.
10.1101/2021.12.18.473326 — Posted: 2021-12-21
SARS-CoV-2 Omicron Variant: ACE2 Binding, Cryo-EM Structure of Spike Protein-ACE2 Complex and Antibody Evasion
Mannar, D., Saville, J. W., Zhu, X., Srivastava, S. S., Berezuk, A. M., Tuttle, K., Marquez, C., Sekirov, I., Subramaniam, S.
10.1101/2021.12.19.473380 — Posted: 2021-12-21
Human genetic variants associated with COVID-19 severity are enriched in immune and epithelium regulatory networks
Feng, Z., Ren, X., Duren, Z., Wang, Y.
10.1101/2021.12.17.473140 — Posted: 2021-12-21
SARS-CoV-2 Omicron spike mediated immune escape, infectivity and cell-cell fusion
Meng, B., Ferreira, I., Abdullahi, A., Kemp, S. A., Goonawardane, N., Papa, G., Fatihi, S., Charles, O., Collier, D., CITIID-NIHR BioResource COVID-19 Collaboration, , The Genotype to Phenotype Japan (G2P-Japan) Consortium, , Choi, J., Hyeon Lee, J., Mlcochova, P., James, L., Doffinger, R., Thukral, L., Sato, K., Gupta, R. K.
10.1101/2021.12.17.473248 — Posted: 2021-12-21
A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors
Chen, K.-Y., Krischuns, T., Ortega Varga, L., Harigua-Souiai, E., Paisant, S., Zettor, A., Chiaravalli, J., Courtney, D., O'Brien, A., Baker, S., Isel, C., Agou, F., Jacob, Y., Blondel, A., Naffakh, N.
10.1101/2021.12.18.473303 — Posted: 2021-12-21
APOBEC-mediated Editing of SARS-CoV-2 Genomic RNA Impacts Viral Replication and Fitness
Chen, X., Kim, K., Calabrese, P., Wang, S., Qin, C., Rao, Y., Feng, P.
10.1101/2021.12.18.473309 — Posted: 2021-12-21
ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection
Ching, K. L., de Vries, M., Gago, J., Dancel-Manning, K., Sall, J., Rice, W. J., Barnett, C., Liang, F.-X., Thorpe, L. E., Shopsin, B., Segal, L. N., Dittmann, M., Torres, V. J., Cadwell, K.
10.1101/2021.12.17.473223 — Posted: 2021-12-20
Evidence for a Potential Pre-Pandemic SARS-like Coronavirus Among Animals in North America
Hancock, T. J., Hickman, P., Kazerooni, N., Kennedy, M., Kania, S. A., Dennis, M., Szafranski, N., Gerhold, R. W., Su, C., Masi, T. J., Smith, S., Sparer, T. E.
10.1101/2021.12.17.473265 — Posted: 2021-12-20
A Computational Dissection of Spike protein of SARS-CoV-2 Omicron Variant
Rehman, Z., Umair, M., Ikram, A., Salman, M., Haider, S. A., Ammar, M.
10.1101/2021.12.17.473260 — Posted: 2021-12-20 Discussion: Onsite
The rise and fall of SARS-CoV-2 variants and the mutational profile of Omicron
Wiegand, T. R., McVey, A., Nemudraia, A., Nemudryi, A., Wiedenheft, B.
10.1101/2021.12.16.473096 — Posted: 2021-12-20

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).