COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,235 Articles (22,733 medRxiv, 8,502 bioRxiv)

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SARS-CoV-2 triggers Golgi fragmentation via downregulation of GRASP55 to facilitate viral trafficking
Zhang, J., Kennedy, A., Xing, L., Bui, S., Reid, W., Joppich, J., Ahat, E., Rose, M., Tang, Q., Tai, A. W., Wang, Y.
10.1101/2022.03.04.483074 — Posted: 2022-03-07
Predicted binding interface between coronavirus nsp3 and nsp4
Hensel, Z.
10.1101/2022.03.05.483145 — Posted: 2022-03-07
Intragenomic rearrangements of SARS-CoV-2 and other β-coronaviruses
Patarca, R., Haseltine, W. A.
10.1101/2022.03.07.483258 — Posted: 2022-03-07
mRNA-based vaccine candidate COReNAPCIN(R) induces robust humoral and cellular immunity in mice and non-human primates
Alimohammadi, R., Porgoo, M., Eftekhary, M., Kiaie, S. H., Ansari Dezfouli, E., Dehghani, M., Nasrollah, K., Malekshahab, T., Heidari, M., Pouya, S., Alimohammadi, M., Sattari Khavas, D., Modaresi, M. S., Ghasemi, M. H., Ramyar, H., Mohammadipour, F., Hamzelouei, F., Mofayezi, A., Mottaghi, S. S., Rahmati, A., Razzaznian, M., Tirandazi, V., Borzouee, F., Sadeghi, H., Haji Mohammadi, M., Rastegar, L., Safar Sajadi, S. M., Ehsanbakhsh, H., Bazmbar, H., Shams Nouraee, M., Pazooki, P., Pahlevan Neshan, M., Alishah, K., Nasiri, F., Mokhberian, N., Mohammadi, S. S., Akar, S., Niknam, H., Azizi, M., Ajoudanian, M., Moteallehi-Ardakani, M. H., Mousavi Shaegh, S. A., Ramezani, R., Salimi, V., Moazzami, R., Hashemi, S. M., Dehghanizadeh, S., Khoddami, V.
10.1101/2022.03.05.483092 — Posted: 2022-03-07
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease
Zhou, P., Song, G., He, W.-t., Beutler, N., Tse, L. V., Martinez, D. R., Schafer, A., Anzanello, F., Yong, P., Peng, L., Dueker, K., Musharrafieh, R., Callaghan, S., Capozzola, T., Yuan, M., Liu, H., Limbo, O., Parren, M., Garcia, E., Rawlings, S. A., Smith, D. M., Nemazee, D., Jardine, J. G., Wilson, I. A., Safonova, Y., Rogers, T., Baric, R. S., Gralinski, L. E., Burton, D. R., Andrabi, R.
10.1101/2022.03.04.479488 — Posted: 2022-03-07
Potent universal-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing monoclonal antibody
Piepenbrink, M. S., Park, J.-G., Deshpande, A., Loos, A., Ye, C., Basu, M., Sarkar, S., Chauvin, D., Woo, J., Lovalenti, P., Erdmann, N. B., Goepfert, P. A., Truong, V. L., Bowen, R. A., Walter, M. R., Martinez-Sobrido, L., Kobie, J. J.
10.1101/2022.03.05.483133 — Posted: 2022-03-07
Discovery of Potent Pyrazoline-Based Covalent SARS-CoV-2 Main Protease Inhibitors
Moon, P., Boike, L., Dovala, D., Henning, N. J., Knapp, M., Spradlin, J. N., Ward, C. C., Wolleb, H., Zammit, C. M., Fuller, D., Blake, G., Murphy, J. P., Wang, F., Lu, Y., Moquin, S. A., Tandeske, L., Hesse, M. J., McKenna, J. M., Tallarico, J., Schirle, M., Toste, F. D., Nomura, D. K.
10.1101/2022.03.05.483025 — Posted: 2022-03-07
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication
Moll, T., Odon, V., Harvey, C., Collins, M., Peden, A., Franklin, J., Graves, E., Marshall, J., dos Santos Souza, C., Zhang, S., Azzouz, M., Gordon, D., Krogan, N., Ferraiuolo, L., Snyder, M., Shaw, P., Rehwinkel, J., Cooper-Knock, J.
10.1101/2022.03.06.483172 — Posted: 2022-03-07
Crippled Coronavirus: 5'-PolyU targeted Oligo prevents development of infectious Virions
Ullah, H., Averick, S., Tang, Q.
10.1101/2022.03.04.483076 — Posted: 2022-03-07
Chimeric mRNA based COVID-19 vaccine elicits potent neutralizing antibodies and protection against Omicron and Delta
Hu, Q., Zhao, Y., Shaabani, N., Lyu, X., Sun, H., Cruz, V., Kao, Y., Xu, J., Fossier, A., Stegman, K., Wang, Z., Wang, Z., Hu, Y., Zheng, Y., Kyaw, L., Zuluaga, C., Wang, H., Pei, H., Powers, C., Allen, R., Xie, H., Ji, H., Chen, R.
10.1101/2022.03.04.483032 — Posted: 2022-03-07

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).