COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,788 Articles (22,946 medRxiv, 8,842 bioRxiv)

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Machine learning-driven COVID-19 early triage and large-scale testing strategies based on the 2021 Costa Rican Actualidades survey
Pasquier, C., Solis, M., Vilchez, V., Nunez-Corrales, S.
10.1101/2024.04.02.24305223 — Posted: 2024-04-03
Mutational pressure drives enhanced release of proteasome-generated public CD8+ T cell epitopes from SARS-CoV-2 RBD of Omicron and its current lineages
Kudriaeva, A. A., Butenko, I. O., Saratov, G. A., Ri, M., Mokrushina, Y. A., Bondarev, A. A., Evpak, A. S., Smirnov, I. V., Matyushkina, D. S., Gabibov, A. G., Govorun, V. M., Belogurov, A. A.
10.1101/2024.04.03.24305074 — Posted: 2024-04-03
Molecular epidemiology of invasive Group A Streptococcal infections before and after the COVID-19 pandemic in Switzerland
Andrianaki, A. M., Franz, J., Andreoni, F., Bergada-Pijuan, J., Scheier, T. C., Duwe, T., Pfister, M., Seth-Smith, H., Roloff, T., Kolesnik-Goldmann, N., Burkhard, S. H., Cusini, A., Karrer, U., Rueegg, C., Schibli, A., Schrenzel, J., Musumeci, S., Kouyos, R. D., Egli, A., Brugger, S. D., Zinkernagel, A. S.
10.1101/2024.04.03.24305261 — Posted: 2024-04-03
Predicting Functional Conformational Ensembles and Binding Mechanisms of Convergent Evolution for SARS-CoV-2 Spike Omicron Variants Using AlphaFold2 Sequence Scanning Adaptations and Molecular Dynamics Simulations
Raisinghani, N., Alshahrani, M., Gupta, G., Xiao, S., Tao, P., Verkhivker, G.
10.1101/2024.04.02.587850 — Posted: 2024-04-03
Discovery of RdRp Thumb-1 as a novel broad-spectrum antiviral family of targets and MDL-001 as a potent broad-spectrum inhibitor thereof - Part I: A Bioinformatics and Deep Learning Approach
Woods, V., Umansky, T., Ramesh, N., Russell, S. M., Garvey, D., Smith, D. M., Haders, D.
10.1101/2024.03.29.587401 — Posted: 2024-04-03
Distal Protein-Protein Interactions Contribute to SARS-CoV-2 Main Protease Substrate Binding and Nirmatrelvir Resistance
Lewandowski, E. M., Zhang, X., Tan, H., Jaskolka-Brown, A., Kohaal, N., Frazier, A., Madsen, J. J., Jacobs, L. M. C., Wang, J., Chen, Y.
10.1101/2024.04.01.587566 — Posted: 2024-04-02
Mapping immunodominant sites on the MERS-CoV spike glycoprotein targeted by infection-elicited antibodies in humans
Addetia, A., Stewart, C., Seo, A. J., Sprouse, K. R., Asiri, A. Y., Al-Mozaini, M., Memish, Z. A., Alshukairi, A., Veesler, D.
10.1101/2024.03.31.586409 — Posted: 2024-04-02
Biologically informed machine learning modeling of immune cells to reveal physiological and pathological aging process
Xia, Z., Zhang, B., Sun, L., Zhang, C., Ren, T., Zhao, X., Su, Y., Wang, Q., Zhang, T., He, B., Wu, L.-Y.
10.1101/2024.04.01.587649 — Posted: 2024-04-02
Single-cell analysis of lung epithelial cells reveals age and cell population-specific responses to SARS-CoV-2 infection in ciliated cells
Osborn, R. M., Anderson, C. S., Leach, J. R., Chu, C.-Y., Dewhurst, S., Mariani, T. J., Thakar, J.
10.1101/2024.04.02.587663 — Posted: 2024-04-02
CovTransformer: A transformer model for SARS-CoV-2 lineage frequency forecasting
Feng, Y., Goldberg, E. E., Kupperman, M., Zhang, X., Lin, Y., Ke, R.
10.1101/2024.04.01.24305089 — Posted: 2024-04-01

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).