COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,442 Articles (22,835 medRxiv, 8,607 bioRxiv)

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Fast isolation of sub-nanomolar affinity alpaca nanobody against the Spike RBD of SARS-CoV-2 by combining bacterial display and a simple single-step density gradient selection
Valenzuela Nieto, G. E., Jara, R., Himelreichs, J., Salinas, C., Pinto, T., Cheuquemilla, Y., Margolles, Y., Lopez Gonzalez del Rey, N., Miranda Chacon, Z., Cuevas, A., Berking, A., Deride, C., Gonzalez-Moraga, S., Mancilla, H., Maturana, D., Langer, A., Toledo, J. P., Müller, A., Uberti, B., Krall, P., Ehrenfeld, P., Blesa, J., Chana-Cuevas, P., Rehren, G., Fernandez, L. A., Rojas-Fernandez, A.
10.1101/2020.06.09.137935 — Posted: 2020-06-10
The impact of viral transport media on PCR assay results for the detection of nucleic acid from SARS-CoV-2 and other viruses
Kirkland, P. D., Frost, M. J.
10.1101/2020.06.09.142323 — Posted: 2020-06-10
Evaluating the efficacy of RT-qPCR SARS-CoV-2 direct approaches in comparison to RNA extraction
Israeli, O., Beth-Din, A., Paran, N., Stein, D., Lazar, S., Weiss, S., Milrot, E., Atiya-Nasagi, Y., Yitzhaki, S., Laskar, O., Schuster, O.
10.1101/2020.06.10.144196 — Posted: 2020-06-10
Prolonged SARS-CoV-2 Viral Shedding in Patients with COVID-19 was Associated with Delayed Initiation of Arbidol Treatment: a retrospective cohort study
Zhou, Y., He, X., Zhang, J., Xue, Y. e., Liang, M., Yang, B., Ma, W., Zhou, Q., Chen, L., Wang, X.
10.1101/2020.06.09.20076646 — Posted: 2020-06-10
Stability of SARS-CoV-2 Phylogenies
Turakhia, Y., Thornlow, B., Gozashti, L., Hinrichs, A., Fernandes, J., Haussler, D., Corbett-Detig, R.
10.1101/2020.06.08.141127 — Posted: 2020-06-09
Insight into vaccine development for Alpha-coronaviruses based on structural and immunological analyses of spike proteins
Shi, Y., Shi, J., Sun, L., Tan, Y., Wang, G., Guo, F., Hu, G., Fu, Y., Fu, Z. F., Xiao, S., Peng, G.
10.1101/2020.06.09.141580 — Posted: 2020-06-09
Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion
Ding, S., Zang, R., Case, J. B., Gomez Castro, M. F., Liu, Z., Zeng, Q., Zhao, H., Son, J., Rothlauf, P. W., Hou, G., Bose, S., Wang, X., Vahey, M. D., Kirchhausen, T., Fremont, D. H., Diamond, M. S., Whelan, S. P. J.
10.1101/2020.06.08.141077 — Posted: 2020-06-09 Discussion: Onsite | Offsite
Structural basis of a public antibody response to SARS-CoV-2
Yuan, M., Liu, H., Wu, N. C., Lee, C.-C. D., Zhu, X., Zhao, F., Huang, D., Yu, W., Hua, Y., Tien, H., Rogers, T. F., Landais, E., Sok, D., Jardine, J. G., Burton, D. R., Wilson, I. A.
10.1101/2020.06.08.141267 — Posted: 2020-06-09
Molecular modelling predicts SARS-CoV-2 ORF8 protein and human complement Factor 1 catalytic domain sharing common binding site on complement C3b
Singh, J., Kar, S., Ganguly, S., Hasnain, S. E.
10.1101/2020.06.08.107011 — Posted: 2020-06-09
The hypothalamus as a hub for putative SARS-CoV-2 brain infection
Nampoothiri, S., Sauve, F., Ternier, G., Fernandois, D., Coelho, C., Imbernon, M., Deligia, E., Perbet, R., Florent, V., Baroncini, M., Pasquier, F., Trottein, F., Maurage, C.-A., Mattot, V., Giacobini, P., Rasika, S., Prevot, V.
10.1101/2020.06.08.139329 — Posted: 2020-06-09 Discussion: Onsite

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).