COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,187 Articles (22,713 medRxiv, 8,474 bioRxiv)

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SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface
Bertoglio, F., Meier, D., Langreder, N., Steinke, S., Rand, U., Simonelli, L., Heine, P. A., Ballmann, R., Schneider, K.-T., Roth, K. D. R., Ruschig, M., Riese, P., Eschke, K., Kim, Y., Schaeckermann, D., Pedotti, M., Kuhn, P., Zock-Emmenthal, S., Woehrle, J., Becker, M., Grashoff, M., Wenzel, E. V., Russo, G., Kroeger, A., Brunotte, L., Ludwig, S., Fuehner, V., Kraemer, S. D., Duebel, S., Varani, L., Roth, G., Cicin-Sain, L., Schubert, M., Hust, M.
10.1101/2020.06.05.135921 — Posted: 2020-06-05 Discussion: Onsite | Offsite
Comparative study of four SARS-CoV-2 Nucleic Acid Amplification Test (NAAT) platforms demonstrates that ID NOW performance is impaired substantially by patient and specimen type.
Lephart, P. R., Bachman, M. A., LeBar, W., McClellan, S. W., Barron, K., Schroeder, L., Newton, D. W.
10.1101/2020.06.04.135616 — Posted: 2020-06-05
Design of a Novel Multiplex Real Time RT-PCR Assay for SARS-CoV-2 Detection
Zhen, W., Berry, G. J.
10.1101/2020.06.04.135608 — Posted: 2020-06-05
An OpenData portal to share COVID-19 drug repurposing data in real time
Brimacombe, K. R., Zhao, T., Eastman, R. T., Hu, X., Wang, K., Backus, M., Baljinnyam, B., Chen, C. Z., Chen, L., Eicher, T., Ferrer, M., Fu, Y., Gorshkov, K., Guo, H., Hanson, Q. M., Itkin, Z., Kales, S. C., Klumpp-Thomas, C., Lee, E. M., Michael, S., Mierzwa, T., Patt, A., Pradhan, M., Renn, A., Shinn, P., Shrimp, J. H., Viraktamath, A., Wilson, K. M., Xu, M., Zakharov, A. V., Zhu, W., Zheng, W., Simeonov, A., Mathe, E. A., Lo, D. C., Hall, M. D., Shen, M.
10.1101/2020.06.04.135046 — Posted: 2020-06-05
Ultra-sensitive nanozyme-based chemiluminescence paper test for rapid diagnosis of SARS-CoV-2 infection
Liu, D., Ju, C., Han, C., Shi, R., Chen, X., Duan, D., Yan, J., Yan, X.
10.1101/2020.06.05.131748 — Posted: 2020-06-05
Several FDA-approved drugs effectively inhibit SARS-CoV-2 infection in vitro
Xiong, H.-L., Cao, J.-L., Shen, C.-G., Ma, J., Qiao, X., Shi, T., Yang, Y., Ge, S.-X., Zhang, J., Zhang, T.-Y., Yuan, Q., Xia, N.-S.
10.1101/2020.06.05.135996 — Posted: 2020-06-05
Characterization of the substitution hotspots in SARS-CoV-2 genome using BioAider and detection of a SR-rich region in N protein providing further evidence of its animal origin
Zhou, Z.-J., Qiu, Y., Ge, X.-Y.
10.1101/2020.06.04.135293 — Posted: 2020-06-05
Tocilizumab is associated with reduction of the risk of ICU admission and mortality in patients with SARS-CoV-2 infection
Moreno Garcia, E., Rico Caballero, V., Albiach, L., Aguero, D., Ambrosioni, J., Bodro, M., Cardozo, C., Chumbita, M., De la Mora, L., Garcia Pouton, N., Garcia Vidal, C., GonzalezCordon, A., Hernandez Meneses, M., Inciarte, A., Laguno, M., Leal, L., Linares, L., Macaya, I., Meira, F., Mensa, J., Moreno, A., Morata, L., Puerta Alcalde, P., Rojas, J., Sola, M., Torres, B., Torres, M., Tome, A., Castro, P., Fernandez, S., Nicolas, J. M., Almuedo Riera, A., Munoz, J., Fernandez, M. J., Marcos, M. A., Soy, D., Martinez, J. A., Garcia, F., Soriano, A.
10.1101/2020.06.05.20113738 — Posted: 2020-06-05
Mechanical ventilation utilization in COVID-19: A systematic review and meta-analysis
Almeshari, M. A., Alobaidi, N. Y., Al Asmri, M., Alhuthail, E., Alshehri, Z., Alenezi, F., Sapey, E., Parekh, D.
10.1101/2020.06.04.20122069 — Posted: 2020-06-05
Extended use or re-use of single-use surgical masks and filtering facepiece respirators: A rapid evidence review
Toomey, E., Conway, Y., Burton, C., Smith, S., Smalle, M., Chan, X.-H., Adisesh, A., Tanveer, S., Ross, L., Thomson, I., Devane, D., Greenhalgh, T.
10.1101/2020.06.04.20121947 — Posted: 2020-06-05

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).