COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,702 Articles (22,913 medRxiv, 8,789 bioRxiv)

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Clearing the fog: Is HCQ effective in reducing COVID-19 progression: A randomized controlled trial
kamran, s. m., Mirza, Z. e. H., Naseem, A., Saeed, F., Azam, R., Ullah, N., Ahmad, W., Saleem, S.
10.1101/2020.07.30.20165365 — Posted: 2020-08-04 Discussion: Onsite
Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic
Gordenin, D. A., Klimczak, L. J., Randall, T. A., Saini, N., Li, J.-L.
10.1101/2020.08.03.234005 — Posted: 2020-08-03 Discussion: Onsite
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
Baker, D., Cao, L., Goreshnik, I., Coventry, B., Case, J. B., Miller, L., Kozodoy, L., Chen, R. E., Carter, L., Walls, A., Park, Y.-J., Stewart, L., Diamond, M., Veesler, D.
10.1101/2020.08.03.234914 — Posted: 2020-08-03 Discussion: Onsite
PAN-INDIA 1000 SARS-CoV-2 RNA Genome Sequencing Reveals Important Insights into the Outbreak
Maitra, A., Raghav, S., Dalal, A., Ali, F., Paynter, V. M., Paul, D., Biswas, N. K., Ghosh, A., Jani, K., Chinnaswamy, S., Pati, S., Sahu, A., Mitra, D., Bhat, M. K., Mayor, S., Sarin, A., The PAN-INDIA 1000 SARS-CoV-2 RNA Genome Sequencing Consortium, , Shouche, Y. S., Seshasayee, A. S. N., Palakodeti, D., Bashyam, M. D., PARIDA, A., Das, S.
10.1101/2020.08.03.233718 — Posted: 2020-08-03
Structure-Based Design of a Cyclic Peptide Inhibitor of the SARS-CoV-2 Main Protease
Kreutzer, A. G., Krumberger, M., Parrocha, C. M. T., Morris, M. A., Guaglianone, G., Nowick, J. S.
10.1101/2020.08.03.234872 — Posted: 2020-08-03
De novo design of ACE2 protein decoys to neutralize SARS-CoV-2
Linsky, T. W., Vergara, R., Codina, N., Nelson, J. W., Walker, M. J., Su, W., Hsiang, T.-Y., Esser-Nobis, K., Yu, K., Hou, Y. J., Priya, T., Mitsumoto, M., Pong, A., Lau, U. Y., Mason, M. L., Chen, J., Chen, A., Berrocal, T., Peng, H., Clairmont, N. S., Castellanos, J., Lin, Y.-R., Josephson-Day, A., Baric, R. S., Walkey, C. D., Swanson, R., Blancas-Mejia, L. M., Gale, M., Yen, H.-L., Silva, D.-A.
10.1101/2020.08.03.231340 — Posted: 2020-08-03
Structure of SARS-CoV-2 2'-O-methyltransferase heterodimer with RNA Cap analog and sulfates bound reveals new strategies for structure-based inhibitor design
Rosas-Lemus, M., Minasov, G., Shuvalova, L., Inniss, N., Kiryukhina, O., Brunzelle, J., Satchell, K. J.
10.1101/2020.08.03.234716 — Posted: 2020-08-03
Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity
Liu, H., Wu, N. C., Yuan, M., Bangaru, S., Torres, J. L., Caniels, T. G., van Schooten, J., Zhu, X., Lee, C.-C. D., Brouwer, P. J. M., van Gils, M. J., Sanders, R. W., Ward, A. B., Wilson, I. A.
10.1101/2020.08.02.233536 — Posted: 2020-08-03
SARS-CoV-2 ORF6 disrupts nucleocytoplasmic transport through interactions with Rae1 and Nup98
Addetia, A., Lieberman, N. A. P., Phung, Q., Xie, H., Roychoudhury, P., Loprieno, M. A., Huang, M., Shrestha, L., Jerome, K. R., Greninger, A. L.
10.1101/2020.08.03.234559 — Posted: 2020-08-03
Functional immune mapping with deep-learning enabled phenomics applied to immunomodulatory and COVID-19 drug discovery
Cuccarese, M. F., Earnshaw, B. A., Heiser, K., Fogelson, B., Davis, C. T., McLean, P. F., Gordon, H. B., Skelly, K.-R., Weathersby, F. L., Rodic, V., Quigley, I. K., Pastuzyn, E. D., Mendivil, B. M., Lazar, N. H., Brooks, C. A., Carpenter, J., Jacobson, P., Glazier, S. W., Ford, J., Jensen, J. D., Campbell, N. D., Statnick, M. A., Low, A. S., Thomas, K. R., Carpenter, A. E., Hegde, S. S., Alfa, R. W., Victors, M. L., Haque, I. S., Chong, Y. T., Gibson, C. C.
10.1101/2020.08.02.233064 — Posted: 2020-08-03

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