COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,082 Articles (22,658 medRxiv, 8,424 bioRxiv)

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Introduction of two prolines and removal of the polybasic cleavage site leads to optimal efficacy of a recombinant spike based SARS-CoV-2 vaccine in the mouse model
Amanat, F., Strohmeier, S., Rathnasinghe, R., Schotsaert, M., Coughlan, L., Garcia-Sastre, A., Krammer, F.
10.1101/2020.09.16.300970 — Posted: 2020-09-18
Mutational signatures in countries affected by SARS-CoV-2: Implications in host-pathogen interactome
Rahman, S. A., Singh, J., Singh, H., Hasnain, S. E.
10.1101/2020.09.17.301614 — Posted: 2020-09-17
Fixed single-cell RNA sequencing for understanding virus infection and host response
Phan, H. V., van Gent, M., Drayman, N., Basu, A., Gack, M., Tay, S.
10.1101/2020.09.17.302232 — Posted: 2020-09-17
Structural and Functional Comparison of SARS-CoV-2-Spike Receptor Binding Domain Produced in Pichia pastoris and Mammalian Cells
Argentinian AntiCovid Consortium, , Arbeitman, C. R., Auge, G., Blaustein, M., Bredeston, L., Corapi, E. S., Craig, P. O., Cossio, L. A., Dain, L., D'Alessio, C., Elias, F., Fernandez, N. B., Gasulla, J., Gorojovsky, N., Gudesblat, G. E., Herrera, M. G., Ibanez, L. I., Idrovo, T., Iglesias Rando, M., Kamenetzky, L., Nadra, A. D., Noseda, D. G., Pavan, C. H., Pavan, M. F., Pignataro, M. F., Roman, E., Ruberto, L. A. M., Rubinstein, N., Santos, J., Velazquez, F., Zelada, A. M.
10.1101/2020.09.17.300335 — Posted: 2020-09-17 Discussion: Offsite
Topography, spike dynamics and nanomechanics of individual native SARS-CoV-2 virions
Kiss, B., Kis, Z., Palyi, B., Kellermayer, M.
10.1101/2020.09.17.302380 — Posted: 2020-09-17 Discussion: Onsite
Discovery of human ACE2 variants with altered recognition by the SARS-CoV-2 spike protein
Heinzelman, P., Romero, P. A.
10.1101/2020.09.17.301861 — Posted: 2020-09-17
Comparison of Rhesus and Cynomolgus macaques as an authentic model for COVID-19.
Salguero, F. J., White, A. D., Slack, G. S., Fotheringham, S. A., Bewley, K. R., Gooch, K. E., Longet, S., Humphries, H. E., Watson, R. J., Hunter, L., Ryan, K. A., Hall, Y., Sibley, L., Sarfas, C., Allen, L., Aram, M., Brunt, E., Brown, P., Buttigieg, K. R., Cavell, B. E., Cobb, R., Coombes, N. S., Daykin-Pont, O., Elmore, M. J., Gkolfinos, K., Godwin, K. J., Gouriet, J., Halkerston, R., Harris, D. J., Hender, T., Ho, C. M. K., Kennard, C. L., Knott, D., Leung, S., Lucas, V., Mabbutt, A., Morrison, A. L., Ngabo, D., Paterson, J., Penn, E. J., Pullan, S., Taylor, I., Tipton, T., Thomas, S., Tree, J. A., Turner, C., Wand, N., Wiblin, N. R., Charlton, S., Hallis, B., Pearson, G., Rayner, E. L., Nicholson, A. G., Funnell, S. G., Dennis, M. J., Gleeson, F. V., Sharpe, S., Carroll, M. W.
10.1101/2020.09.17.301093 — Posted: 2020-09-17
Identification of novel antiviral drug combinations in vitro and tracking their development
Ianevski, A., Yao, R., Biza, S., Zusinaite, E., Mannik, A., Kivi, G., Planken, A., Kurg, K., Tombak, E.-M., Ustav, M., Shtaida, N., Kulesskiy, E., Jo, E., Yang, J., Lysvand, H., Loseth, K., Oksenych, V., Aas, P. A., Tenson, T., Vitkauskiene, A., Windisch, M. P., Fenstad, M. H., Nordbo, S. A., Ustav, M., Bjoras, M., Kainov, D. E.
10.1101/2020.09.17.299933 — Posted: 2020-09-17
A soluble ACE2 microbody protein fused to a single immunoglobulin Fc domain is a potent inhibitor of SARS-CoV-2 infection in cell culture
Tada, T., Fan, C., Kaur, R., Stapleford, K. A., Gristick, H., Nimigean, C., Landau, N. R.
10.1101/2020.09.16.300319 — Posted: 2020-09-17
Distinct SARS-CoV-2 Antibody Reactivity Patterns in Coronavirus Convalescent Plasma Revealed by a Coronavirus Antigen Microarray
Ramiro de Assis, R., Jain, A., Nakajima, R., Jasinskas, A., Khan, S., Dumont, L. J., Kelly, K., Simmons, G., Stone, M., Di Germanio, C., Busch, M. P., Felgner, P. L.
10.1101/2020.09.16.300871 — Posted: 2020-09-17

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).