COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,362 Articles (22,803 medRxiv, 8,559 bioRxiv)

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Structural dynamics of the β-coronavirus Mpro protease ligand binding sites
Cho, E., Rosa, M., Anjum, R., Mehmood, S., Soban, M., Mujtaba, M., Bux, K., Dantu, S. C., Pandini, A., Yin, J., Ma, H., Ramanathan, A., Islam, B., Mey, A., BHOWMIK, D., Haider, S.
10.1101/2021.03.31.437918 — Posted: 2021-04-01
Hydrogel-based slow release of a receptor-binding domain subunit vaccine elicits neutralizing antibody responses against SARS-CoV-2
Gale, E. C., Powell, A. E., Roth, G. A., Ou, B. S., Meany, E. L., Grosskopf, A. K., Adamska, J., Picece, V. C. T. M., d'Aquino, A. I., Pulendran, B., Kim, P. S., Appel, E.
10.1101/2021.03.31.437792 — Posted: 2021-04-01
An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces sterile immunity and prevents transmission of SARS-CoV-2 between cats
Langereis, M. A., Stachura, K., Miller, S., Bosco-Lauth, A. M., Albulescu, I. C., Hartwig, A. E., Porter, S. M., Stammen-Vogelzangs, J., Mogler, M., van Kuppeveld, F. J. M., Bosch, B. J., Vermeij, P., de Groof, A., Bowen, R. A., Davis, R., Xu, Z., Tarpey, I.
10.1101/2021.04.01.436305 — Posted: 2021-04-01
Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry
Kastenhuber, E. R., Jaimes, J. A., Johnson, J. L., Mercadante, M., Muecksch, F., Weisblum, Y., Bram, Y., Schwartz, R. E., Whittaker, G. R., Cantley, L. C.
10.1101/2021.03.31.437960 — Posted: 2021-04-01
Screening of HLA-A restricted T cell epitopes of SARS-CoV-2 and induction of CD8+ T cell responses in HLA-A transgenic mice
Jin, X., Ding, Y., Sun, S., Wang, X., Zhou, Z., Liu, X., Li, M., Chen, X., Shen, A., Wu, Y., Liu, B., Zhang, J., Li, J., Yang, Y., Qiu, H., Shen, C., He, Y., Zhao, G.
10.1101/2021.04.01.438020 — Posted: 2021-04-01
Limiting the priming dose of a SARS CoV-2 vaccine improves virus-specific immunity
Sanchez, S., Palacio, N., Dangi, T., Ciucci, T., Penaloza-MacMaster, P.
10.1101/2021.03.31.437931 — Posted: 2021-04-01
The neutralization potency of anti-SARS-CoV-2 therapeutic human monoclonal antibodies is retained against novel viral variants
Rosenfeld, R., Mazor, O., Makdasi, E., Zvi, A., Alcalay, R., Noy-Porat, T., Peretz, E., Mechaly, A., Levy, Y., Epstein, E., Chitlaru, T., Paran, N., Tamir, H., Zimhony, O., Weiss, S., Mandelboim, M., Mendelson, E., Zuckerman, N., Nemet, I., Kliker, L., Yitzhaki, S., Shapira, S. C., Israely, T.
10.1101/2021.04.01.438035 — Posted: 2021-04-01
SARS-CoV-2 immune evasion by variant B.1.427/B.1.429
McCallum, M., Bassi, J., De Marco, A., Chen, A., Walls, A. C., Di Iulio, J., Tortorici, M. A., Navarro, M.-J., Silacci-Fregni, C., Saliba, C., Agostini, M., Pinto, D., Culap, K., Bianchi, S., Jaconi, S., Cameroni, E., Bowen, J. E., Tiles, S. W., Pizzuto, M. S., Bernasconi Guastalla, S., Bona, G., Franzetti Pellanda, A., Garzoni, C., Van Voorhis, W. C., Rosen, L. E., Snell, G. C., Telenti, A., Virgin, H. W., Piccoli, L., Corti, D., Veesler, D.
10.1101/2021.03.31.437925 — Posted: 2021-04-01
To knot and not: Multiple conformations of the SARS-CoV-2 frameshifting RNA element
Schlick, T., Zhu, Q., Dey, A., Jain, S., Yan, S., Laederach, A.
10.1101/2021.03.31.437955 — Posted: 2021-04-01
Interim Report: Safety And Immunogenicity Of An Inactivated Vaccine Against Sars-Cov-2 In Healthy Chilean Adults In A Phase 3 Clinical Trial
Bueno, S. M., Abarca, K., Gonzalez, P. A., Galvez, N. M. S., Soto, J. A., Duarte, L. F., Schultz, B. M., Pacheco, G. A., Gonzalez, L. A., Vasquez, Y., Rios, M., Melo-Gonzalez, F., Rivera-Perez, D., Iturriaga, C., Urzua, M., Dominguez, A., Andrade, C. A., Berrios, R. V., Canedo-Marroquin, G., Covian, C., Moreno-Tapia, D., Saavedra, F., Vallejos, O. P., Donato, P., Espinoza, P., Fuentes, D., Gonzalez, M., Guzman, P., Munoz-Venturelli, P., Perez, C. M., Potin, M., Rojas, a., Fasce, R., Fernandez, J., Mora, J., Ramirez, E., Gaete-Argel, A., Oyarzun-Arrau, A., Valiente-Echeverria, F., Soto-Rifo, R., Weiskopf, D., Sette, A., Zeng, G., Meng, W., Gonzalez-Aramundiz, J. V., Kalergis, A. M.
10.1101/2021.03.31.21254494 — Posted: 2021-04-01

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).