COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,432 Articles (22,835 medRxiv, 8,597 bioRxiv)

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Dual roles of a novel oncolytic viral vector-based SARS-CoV-2 vaccine: preventing COVID-19 and treating tumor progression
Caligiuri, M. A., Yu, J., Sun, Y., Dong, W., Tian, L., Rao, Y., Qin, C., Jaramillo, S. A., Settles, E. W., Ma, S., Zhang, J., Yu, K., Xu, B., Yan, J., Ma, R., Li, Z., Dadwal, S. S., Barker, B. M., Keim, P. S., Feng, P.
10.1101/2021.06.07.447286 — Posted: 2021-06-07
Comprehensive analysis of RNA-seq and whole genome sequencing data reveals no evidence for SARS-CoV-2 integrating into host genome
Chen, Y.-S., Lu, S., Zhang, B., Du, T., Li, W.-J., Lei, M., Zhou, Y., Zhang, Y., Liu, P., Sun, Y.-Q., Zhao, Y.-L., Yang, Y., Peng, X., Yang, Y.-G.
10.1101/2021.06.06.447293 — Posted: 2021-06-07
Hot water extract of Arthrospira maxima (AHWE) has broad-spectrum antiviral activity against RNA virus including coronavirus SARS-CoV2, and the antivirus spray application
Chen, Y.-H., Liao, Y.-C., Huang, J. Y., Kung, Y.-A., Chiueh, C.-C.
10.1101/2021.06.06.446935 — Posted: 2021-06-07
The local anaesthetic procaine prodrugs ProcCluster(R) and Procaine-hydrochloride impair SARS-CoV-2 replication in vitro
Häring, C., Schroeder, J., Loeffler, B., Engert, B., Ehrhardt, C.
10.1101/2021.06.07.447335 — Posted: 2021-06-07
B.1.1.7 and B.1.351 variants are highly virulent in K18-ACE2 transgenic mice and show different pathogenic patterns from early SARS-CoV-2 strains
Radvak, P., Kwon, H. J., Kosikova, M., Ortega-Rodriguez, U., Xiang, R., Phue, J.-N., Shen, R.-F., Rozzelle, J., Kapoor, N., Rabara, T., Fairman, J., Xie, H.
10.1101/2021.06.05.447221 — Posted: 2021-06-07
Evolutionary velocity with protein language models
Hie, B. L., Yang, K. K., Kim, P. S.
10.1101/2021.06.07.447389 — Posted: 2021-06-07
E156/G and Arg158, Phe-157/del mutation in NTD of spike protein in B.1.167.2 lineage of SARS-CoV-2 leads to immune evasion through antibody escape
Chaudhari, A., Kumar, D., Joshi, D. M., Patel, A., joshi, P. C.
10.1101/2021.06.07.447321 — Posted: 2021-06-07
Dynamics and self-assembly of the SARS-CoV-2 spike transmembrane domain
Lall, S., Balaram, P., Gosavi, S., Mathew, M. K.
10.1101/2021.06.07.447334 — Posted: 2021-06-07
In vitro evaluation of the effect of mutations in primer binding sites on detection of SARS-CoV-2 by RT-qPCR
Zimmermann, F., Urban, M., Krueger, C., Walter, M., Woelfel, R., Zwirglmaier, K.
10.1101/2021.06.07.447338 — Posted: 2021-06-07
FXR inhibition reduces ACE2 expression, SARS-CoV-2 infection and may improve COVID-19 outcome
Brevini, T., Maes, M., Webb, G. J., Gelson, W. T. H., Forrest, S., Mlcochova, P., Dillon, S., Varankar, S., Darvish-Damavandi, M., Mulcahy, V. L., Kuc, R. E., Williams, T. L., Galanakis, V., Vila-Gonzalez, M., Tysoe, O. C., Muraro, D., Crozier, T. W. M., Bargehr, J., Sinha, S., Upponi, S. S., Swift, L., Saeb-Parsy, K., Davies, S. E., Marjot, T., Barnes, E., Lohse, A. W., Moon, A. M., Barritt, S. A., Gupta, R. K., Baker, S., Davenport, A. P., Corbett, G., Buczacki, S. J. A., Lee, J.-H., Gibbs, P., Butler, A. J., Watson, C. J. E., Mells, G. F., Dougan, G., vallier, L., Sampaziotis, F.
10.1101/2021.06.06.446781 — Posted: 2021-06-07

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).