COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,384 Articles (22,816 medRxiv, 8,568 bioRxiv)

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Fourteen-days Evolution of COVID-19 Symptoms During the Third Wave in Non-vaccinated Subjects and Effects of Hesperidin Therapy: A randomized, double-blinded, placebo-controlled study.
Dupuis, J., Laurin, P., Tardif, J.-C., Hausermann, L., Rosa, C., Guertin, M.-C., Thibaudeau, K., Gagnon, L., Cesari, F., Robitaille, M., Moran, J. E.
10.1101/2021.10.04.21264483 — Posted: 2021-10-05
SARS-CoV-2 genome sequences from Lucknow, Uttar Pradesh, India by Nanopore Sequencing
Sahoo, B., Maurya, P. K., Tripathi, R. K., Agarwal, J., Tiwari, S.
10.1101/2021.10.05.463185 — Posted: 2021-10-05
TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques
Upadhyay, A. A., Hoang, T. N., Pino, M., Boddapati, A. K., Viox, E. G., Lee, M. Y. H., Corry, J., Strongin, Z., Cowan, D. A., Beagle, E. N., Horton, T. R., Hamilton, S., Aoued, H., Harper, J. L., Nguyen, K., Pellegrini, K. L., Tharp, G. K., Piantadosi, A., Levit, R. D., Amara, R. R., Barratt-Boyes, S. M., Ribeiro, S. P., Sekaly, R. P., Vanderford, T. H., Schinazi, R. F., Paiardini, M., Bosinger, S. E.
10.1101/2021.10.05.463212 — Posted: 2021-10-05
Genetic association of TMPRSS2 rs2070788 polymorphism with COVID-19 Case Fatality Rate among Indian populations
PANDEY, R. K., Srivastava, A., Singh, P. P., Chaubey, G.
10.1101/2021.10.04.463014 — Posted: 2021-10-05
B.1.617.3 SARS CoV-2 spike E156G/Δ157-158 mutations contribute to reduced neutralization sensitivity and increased infectivity
Mishra, T., Joshi, G., Kumar, A., Dalavi, R., Pandey, P., Shukla, S., Mishra, R. K., Chande, A.
10.1101/2021.10.04.463028 — Posted: 2021-10-05
Longitudinal characterization of circulating neutrophils uncovers distinct phenotypes associated with disease severity in hospitalized COVID-19 patients
LaSalle, T. J., Gonye, A. L. K., Freeman, S. S., Kaplonek, P., Gushterova, I., Kays, K. R., Manakongtreecheep, K., Tantivit, J., Rojas-Lopez, M., Russo, B. C., Sharma, N., Thomas, M. F., Lavin-Parsons, K. M., Lilly, B. M., Mckaig, B. N., Charland, N. C., Khanna, H. K., Lodenstein, C. L., Margolin, J. D., Blaum, E. M., Lirofonis, P. B., Sonny, A., Bhattacharyya, R. P., Parry, B. A., Goldberg, M. B., Alter, G., Filbin, M. R., Villani, A. C., Hacohen, N., Sade-Feldman, M.
10.1101/2021.10.04.463121 — Posted: 2021-10-05
A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry
Xu, M., Pradhan, M., Gorshkov, K., Petersen, J. D., Shen, M., Guo, H., Zhu, W., Klumpp-Thomas, C., Michael, S., Itkin, M., Itkin, Z., Straus, M. R., Zimmerberg, J., Zheng, W., Whittaker, G., Chen, C. Z.
10.1101/2021.10.04.463106 — Posted: 2021-10-05
Lung-selective Cas13d-based nanotherapy inhibits lethal SARS-CoV-2 infection by targeting host protease Ctsl
Cui, Z., Zeng, C., Huang, F., Yuan, F., Yan, J., Zhao, Y., Huang, J., Staats, H. F., Everitt, J. I., Sempowski, G. D., Wang, H., Dong, Y., Liu, S.-L., Wang, Q.
10.1101/2021.10.03.462915 — Posted: 2021-10-05
Oral and intranasal Ad5 SARS-CoV-2 vaccines decrease disease and viral transmission in a golden hamster model
Langel, S. N., Johnson, S., Martinez, C. I., Tedjakusuma, S. N., Peinovich, N., Dora, E. G., Kuehl, P. J., Irshad, H., Barrett, E. G., Werts, A., Tucker, S. N.
10.1101/2021.10.03.462919 — Posted: 2021-10-05 Discussion: Onsite
Acute COVID-19 gene-expression profiles show multiple etiologies of long-term sequelae
Thompson, R. C., Simons, N. W., Wilkins, L., Cheng, E., Del-Valle, D. M., Hoffman, G. E., Fennessy, B., Mouskas, K., Francoeur, N. J., Johnson, J. S., Lepow, L., Le Berichel, J., Chang, C., Beckmann, A. G., Wang, Y.-c., Nie, K., Zaki, N., Tuballes, K., Barcessat, V., Cedillo, M. A., Huckins, L., Roussos, P., Marron, T. U., The Mount Sinai COVID-19 Biobank Team, , Glicksberg, B. S., Nadkarni, G., Gonzalez-Kozlova, E., Kim-Schulze, S., Sebra, R., Merad, M., Gnjatic, S., Schadt, E. E., Charney, A. W., Beckmann, N. D.
10.1101/2021.10.04.21264434 — Posted: 2021-10-05

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).