COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,308 Articles (22,772 medRxiv, 8,536 bioRxiv)

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Comprehensive fitness landscape of SARS-CoV-2 Mpro reveals insights into viral resistance mechanisms
Flynn, J. M., Samant, N., Schneider-Nachum, G., Barkan, D. T., Yilmaz, N. K., Schiffer, C. A., Moquin, S. A., Dovala, D., Bolon, D. N. A.
10.1101/2022.01.26.477860 — Posted: 2022-01-26
SARS-CoV-2 Omicron Variant AI-based Primers
Perez-Romero, C. A., Tonda, A., Mendoza-Maldonado, L., MacSharry, J., Szafran, J., Claassen, E., Garssen, J., Kraneveld, A. D., Lopez-Rincon, A.
10.1101/2022.01.21.475953 — Posted: 2022-01-26
Structural diversity of the SARS-CoV-2 Omicron spike
Gobeil, S., Henderson, R., Stalls, V., Janowska, K., Huang, X., May, A., Speakman, M., Beaudoin, E., Manne, K., Li, D., Parks, R., Barr, M., Deyton, M., Martin, M., Mansouri, K., Edwards, R. J., Sempowski, G. D., Saunders, K. O., Wiehe, K., Williams, W., Korber, B., Haynes, B. F., Acharya, P.
10.1101/2022.01.25.477784 — Posted: 2022-01-26
The SARS-CoV-2 protein NSP2 impairs the microRNA-induced silencing capacity of human cells
Zou, L., Moch, C., GRAILLE, M., Chapat, C.
10.1101/2022.01.25.477753 — Posted: 2022-01-26
Despite the odds: formation of the SARS-CoV-2 methylation complex.
Matsuda, A., Plewka, J., Chykunova, Y., Jones, A. N., Pachota, M., Rawski, M., Mourao, A., Karim, A., Kresik, L., Lis, K., Minia, I., Hartman, K., Sonani, R., Schlauderer, F., Dubin, G., Sattler, M., Suder, P., Popowicz, G., Pyrc, K., Czarna, A.
10.1101/2022.01.25.477673 — Posted: 2022-01-26
Biodistribution and Environmental Safety of a Live-attenuated YF17D-vectored SARS-CoV-2 Vaccine Candidate
Li, L.-H., Liesenborghs, L., Wang, L., Lox, M., Yakass, M. B., Jansen, S., Rosales Rosas, A. L., Zhang, X., Thibaut, H. J., Teuwen, D., Neyts, J., Delang, L., Dallmeier, K.
10.1101/2022.01.24.477505 — Posted: 2022-01-26
Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine
Wu, Y., Wang, S., Zhang, Y., Yuan, L., Zheng, Q., Wei, M., Shi, Y., Wang, Z., Ma, J., Wang, K., Nie, M., Xiao, J., Huang, Z., Chen, P., Guo, H., Lan, M., Xu, J., Hou, W., Hong, Y., Chen, D., Sun, H., Xiong, H., Zhou, M., Liu, C., Guo, W., Guo, H., Gao, J., Li, Z., Zhang, H., Wang, X., Li, S., Cheng, T., Zhao, Q., Chen, Y., Wu, T., Zhang, T., Zhang, J., Cao, H., Zhu, H., Yuan, Q., Guan, Y., Xia, N.
10.1101/2022.01.25.477789 — Posted: 2022-01-26
Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability
Shi, W., Wang, L., Zhou, T., Sastry, M., Yang, E. S., Zhang, Y., Chen, M., Chen, X., Choe, M., Creanga, A., Leung, K., Olia, A. S., Pegu, A., Rawi, R., Shen, C.-H., Stancofski, E.-S. D., Talana, C. A., Teng, I.-T., Wang, S., Corbett, K. S., Tsybovsky, Y., Mascola, J. R., Kwong, P. D.
10.1101/2022.01.25.477770 — Posted: 2022-01-26
Anti-SARS-CoV-2 swine glyco-humanized polyclonal antibody XAV-19 retains neutralizing activity against SARS-CoV-2 B.1.1.529 (Omicron)
Vanhove, B., Marot, S. S., Evanno, G., Mallet, I., Rouvray, G., Shneiker, F., Mevel, E., Ciron, C., Rousse, J., Royer, P.-J., Lheriteau, E., Raffi, F., Duvaux, O., Marcelin, A.-G., Calvez, V.
10.1101/2022.01.26.477856 — Posted: 2022-01-26
Discovery of S-217622, a Non-Covalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19
Unoh, Y., Uehara, S., Nakahara, K., Nobori, H., Yamatsu, Y., Yamamoto, S., Maruyama, Y., Taoda, Y., Kasamatsu, K., Suto, T., Kouki, K., Nakahashi, A., Kawashima, S., Sanaki, T., Toba, S., Uemura, K., Mizutare, T., Ando, S., Sasaki, M., Orba, Y., Sawa, H., Sato, A., Sato, T., Kato, T., Tachibana, Y.
10.1101/2022.01.26.477782 — Posted: 2022-01-26

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).