COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,001 Articles (22,627 medRxiv, 8,374 bioRxiv)

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SARS-CoV-2 nsp1 mediates broad inhibition of translation in mammals
Gen, R., Addetia, A., Asarnow, D., Park, Y.-J., Quispe, J., Chan, M. C., Brown, J. T., Lee, J., Campbell, M. G., Lapointe, C. P., Veesler, D.
10.1101/2025.01.14.633005 — Posted: 2025-01-15
Deciphering the Host-Pathogen Interface in COVID-19: The precision molecular insight into epitranscriptomic modifications of high-impact transcripts
Mazdziarz, M. A., Krawczyk, K., Lepiarczyk, E., Paukszto, L., Makowczenko, K. G., Moczulska, B., Iwanowicz, P., Kocbach, P., Sawicki, J., Gromadzinski, L., Majewska, M.
10.1101/2025.01.14.632961 — Posted: 2025-01-15
Unlocking the Secrets of NSP3: AlphaFold2-assisted Domain Determination in SARS-CoV-2 Protein
Edich, M., Briggs, D., Gao, Y., Thorn, A.
10.1101/2025.01.14.632924 — Posted: 2025-01-15
Trypstatin as a Novel TMPRSS2 Inhibitor with Broad-Spectrum 1 Efficacy Against Corona and Influenza Viruses
Lawrenz, J., Wettstein, L., Rodriguez Alfonso, A., Nchioua, R., von Maltitz, P., Albers, D., Zech, F., Vandeput, J., Stevaert, A., Fois, G., Preising, N., Schmierer, E., Almeida-Hernandez, Y., Petersen, M., Staendker, L., Wiese, S., Braubach, P., Frick, M., Sanchez-Garcia, E., Sauter, D., Kirchhoff, F., Naesens, L., Muench, J.
10.1101/2025.01.14.632953 — Posted: 2025-01-15
Metabolic syndrome enhances SARS-CoV-2 disease severity and reduces mRNA vaccine efficacy in a mouse model
Geeling, E., Stone, E. T., Carpenter, D., Dickson, A., Brien, J., Pinto, A. K.
10.1101/2025.01.15.633120 — Posted: 2025-01-15
A genetically based computational drug repurposing framework for rapid identification of candidate compounds: application to COVID-19
Voloudakis, G., Lee, K. M., Vicari, J., Zhang, W., Hoagland, D., Venkatesh, S., Bian, J., Anyfantakis, M., Wu, Z., Rahman, S., Gao, L., Cho, K., Lee, J. S., Iyengar, S. K., Luoh, S.-W., Assimes, T. L., Hoffman, G., tenOever, B. R., Fullard, J. F., Lynch, J. A., Roussos, P.
10.1101/2025.01.10.25320348 — Posted: 2025-01-14
Metformin on Time to Sustained Recovery in Adults with COVID-19: The ACTIV-6 Randomized Clinical Trial
Bramante, C., Stewart, T. G., Boulware, D., McCarthy, M. W., Gao, Y., Rothman, R. L., Mourad, A., Thicklin, F., Cohen, J., Garcia del Sol, I. T., Ruiz-Unger, J., Shah, N. S., Mehta, M., Quintero Cardona, O., Scott, J., Ginde, A. A., Castro, M., Jayaweera, D., Sulkowski, M., Gentile, N., McTigue, K., Felker, G. M., Collins, S., Dunsmore, S. E., Adam, S. J., Lindsell, C. J., Hernandez, A. F., Naggie, S.
10.1101/2025.01.13.25320485 — Posted: 2025-01-14
Generating cognate epitope sequences of T-cell receptors with a generative transformer
Ma, M., Tu, W., Vasquez-Rios, C., Ding, J.
10.1101/2025.01.13.632824 — Posted: 2025-01-14
Distinct CD8+ T-cell types Associated with COVID-19 Severity in Unvaccinated HLA-A2+ Patients
Masuda, K., Iketani, S., Liu, L., Huang, J., Qiao, Y., Shah, J., McNairy, M. L., Groso, C., Ricupero, C., Loffredo, L. F., Wang, Q., Purpura, L., Coelho-dos-Reis, J. G. A., Sheng, Z., Yin, M. T., Tsuji, M.
10.1101/2025.01.12.632164 — Posted: 2025-01-14
MDL-001: An Oral, Safe, and Well-Tolerated Broad-Spectrum Inhibitor of Viral Polymerases
Woods, V., Umansky, T., Russell, S. M., McGovern, B. L., Rosales, R., Rodriguez, M. L., van Bakel, H., Sordillo, E. M., Simon, V., Garcia-Sastre, A., White, K. M., Smith, D. M., Haders, D.
10.1101/2025.01.13.632836 — Posted: 2025-01-14

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