COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,629 Articles (22,913 medRxiv, 8,716 bioRxiv)

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An exploratory randomized, controlled study on the efficacy and safety of lopinavir/ritonavir or arbidol treating adult patients hospitalized with mild/moderate COVID-19 (ELACOI)
Li, Y., Xie, Z., Lin, W., Cai, W., Wen, C., Guan, Y., Mo, X., Wang, J., Wang, Y., Peng, P., Chen, X., Hong, W., Xiao, G., Liu, J., Zhang, L., Hu, F., Li, F., Li, F., Zhang, F., Deng, X., Li, L.
10.1101/2020.03.19.20038984 — Posted: 2020-03-23
AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system in four weeks
Jin, S., Wang, B., Xu, H., Luo, C., Wei, L., Zhao, W., Hou, X., Ma, W., Xu, Z., Zheng, Z., Sun, W., Lan, L., Zhang, W., Mu, X., Shi, C., Wang, Z., Lee, J., Jin, Z., Lin, M., Jin, H., Zhang, L., Guo, J., Zhao, B., Ren, Z., Wang, S., You, Z., Dong, J., Wang, X., Wang, J., Xu, W.
10.1101/2020.03.19.20039354 — Posted: 2020-03-23
SARS-CoV-2, an evolutionary perspective of interaction with human ACE2 reveals undiscovered amino acids necessary for complex stability
Armijos-Jaramillo, V., Yeager, J., Muslin, C., Perez-Castillo, Y.
10.1101/2020.03.21.001933 — Posted: 2020-03-23
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
Gordon, D. E., Jang, G. M., Bouhaddou, M., Xu, J., Obernier, K., O’Meara, M. J., Guo, J. Z., Swaney, D. L., Tummino, T. A., Hüttenhain, R., Kaake, R. M., Richards, A. L., Tutuncuoglu, B., Foussard, H., Batra, J., Haas, K., Modak, M., Kim, M., Haas, P., Polacco, B. J., Braberg, H., Fabius, J. M., Eckhardt, M., Soucheray, M., Bennett, M. J., Cakir, M., McGregor, M. J., Li, Q., Naing, Z. Z., Zhou, Y., Peng, S., Kirby, I. T., Melnyk, J. E., Chorba, J. S., Lou, K., Dai, S. A., Shen, W., Shi, Y., Zhang, Z., Barrio-Hernandez, I., Memon, D., Hernandez-Armenta, C., Mathy, C. J., Perica, T., Pilla, K. B., Ganesan, S. J., Saltzberg, D. J., Ramachandran, R., Liu, X., Rosenthal, S. B., Calviello, L., Venkataramanan, S., Lin, Y., Wankowicz, S. A., Bohn, M., Trenker, R., Young, J. M., Cavero, D., Hiatt, J., Roth, T., Rathore, U., Subramanian, A., Noack, J., Hubert, M., Roesch, F., Vallet, T., Meyer, B., White, K. M., Miorin, L., Agard, D., Emerman, M., Ruggero, D., García-Sastre, A., Jura, N., Zastrow, M. v., Taunton, J., Schwartz, O., Vignuzzi, M., d’Enfert, C., Mukherjee, S., Jacobson, M., Malik, H. S., Fujimori, D. G., Ideker, T., Craik, C. S., Floor, S., Fraser, J. S., Gross, J., Sali, A., Kortemme, T., Beltrao, P., Shokat, K., Shoichet, B. K., Krogan, N. J.
10.1101/2020.03.22.002386 — Posted: 2020-03-22 Discussion: Onsite | Offsite
Emergence of SARS-CoV-2 through Recombination and Strong Purifying Selection
Li, X., Giorgi, E. E., Marichann, M. H., Foley, B., Xiao, C., Kong, X.-p., Chen, Y., Korber, B., Gao, F.
10.1101/2020.03.20.000885 — Posted: 2020-03-22
Building a COVID-19 Vulnerability Index
DeCaprio, D., Gartner, J. A., Burgess, T., Kothari, S., Sayed, S., McCall, C. J.
10.1101/2020.03.16.20036723 — Posted: 2020-03-21
Development and utilization of an intelligent application for aiding COVID-19 diagnosis
Meng, Z., Wang, M., Song, H., Guo, S., Zhou, Y., Li, W., Zhou, Y., Li, M., Song, X., Zhou, Y., Li, Q., Lu, X., Ying, B.
10.1101/2020.03.18.20035816 — Posted: 2020-03-21
COVID-19 coronavirus vaccine design using reverse vaccinology and machine learning
Ong, E., Wong, M. U., Huffman, A., He, Y.
10.1101/2020.03.20.000141 — Posted: 2020-03-21 Discussion: Onsite | Offsite
Molecular characterization of SARS-CoV-2 in the first COVID-19 cluster in France reveals an amino-acid deletion in nsp2 (Asp268Del)
Bal, A., Destras, G., Gaymard, A., Bouscambert-Duchamp, M., Valette, M., Escuret, V., Frobert, E., Billaud, G., Trouillet-Assant, S., Cheynet, V., Brengel-Pesce, K., Morfin, F., Lina, B., Josset, L.
10.1101/2020.03.19.998179 — Posted: 2020-03-21 Discussion: Onsite
Respiratory disease and virus shedding in rhesus macaques inoculated with SARS-CoV-2
Munster, V., Feldmann, F., Williamson, B., van Doremalen, N., Perez-Perez,, L., Schultz, J., Meade-White, K., Okumura, A., Callison, J., Brumbaugh, B., Avanzato, V., Rosenke, R., Hanley, P., Saturday, G., Scott, D., Fischer, E., de Wit, E.
10.1101/2020.03.21.001628 — Posted: 2020-03-21 Discussion: Onsite

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Subject Areas
* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).