COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,389 Articles (22,816 medRxiv, 8,573 bioRxiv)

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A short therapeutic regimen based on hydroxychloroquine plus azithromycin for the treatment of COVID-19 in patients with non-severe disease. A strategy associated with a reduction in hospital admissions and complications.
Oteo, J. A., Marco, P., Ponce de Leon, L., Roncero, A., Lobera, T., Lisa, V.
10.1101/2020.06.10.20101105 — Posted: 2020-06-12
Hydroxychloroquine Proves Ineffective in Hamsters and Macaques Infected with SARS-CoV-2
Rosenke, K., Jarvis, M., Feldmann, F., Schwarz, B., Okumura, A., Lovaglio, J., Saturday, G., Hanley, P., Meade-White, K., Williamson, B., Hansen, F., Perez-Perez, L., Leventhal, S., Tang-Huau, T.-L., Nason, M., Callison, J., Haddock, E., Scott, D., Sewell, G., Bosio, C., Hawman, D., de Wit, E., Feldmann, H.
10.1101/2020.06.10.145144 — Posted: 2020-06-11 Discussion: Onsite | Offsite
SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness
Corbett, K. S., Edwards, D., Leist, S. R., Abiona, O. M., Boyoglu-Barnum, S., Gillespie, R. A., Himansu, S., Schafer, A., Ziwawo, C. T., DiPiazza, A. T., Dinnon, K. H., Elbashir, S. M., Shaw, C. A., Woods, A., Fritch, E. J., Martinez, D. R., Bock, K. W., Minai, M., Nagata, B. M., Hutchinson, G. B., Bahl, K., Garcia-Dominguez, D., Ma, L., Renzi, I., Kong, W.-P., Schmidt, S. D., Wang, L., Zhang, Y., Stevens, L. J., Phung, E., Chang, L. A., Loomis, R. J., Altaras, N. E., Narayanan, E., Metkar, M., Presnyak, V., Liu, C., Louder, M. K., Shi, W., Leung, K., Yang, E. S., West, A., Gully, K. L., Wang, N., Wrapp, D., Doria-Rose, N. A., Stewart-Jones, G., Bennett, H., Nason, M. C., Ruckwardt, T. J., McLellan, J. S., Denison, M. R., Chappell, J. D., Moore, I. N., Morabito, K. M., Mascola, J. R., Baric, R. S., Carfi, A., Graham, B. S.
10.1101/2020.06.11.145920 — Posted: 2020-06-11 Discussion: Onsite | Offsite
COVID-19 Variants Database: A repository for Human SARS-CoV-2 Polymorphism Data
Rakha, A., Rasheed, H., Batool, Z., Akram, J., Adnan, A., Du, J.
10.1101/2020.06.10.145292 — Posted: 2020-06-11 Discussion: Onsite
Investigation of the effect of temperature on the structure of SARS-Cov-2 Spike Protein by Molecular Dynamics Simulations
Rath, S. L., Kumar, K.
10.1101/2020.06.10.145086 — Posted: 2020-06-11
Hijacking SARS-Cov-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on receptor binding region
Carino, A., Moraca, F., Fiorillo, B., Marcano, S., Sepe, V., Biagioli, M., Finamore, C., Bozza, S., Francisci, D., Distrutti, E., Catalanotti, B., Zampella, A., Fiorucci, S.
10.1101/2020.06.10.144964 — Posted: 2020-06-11
Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests.
Madala, B. S., Reis, A. L. M., Deveson, I. W., Rawlinson, W., Mercer, T. R.
10.1101/2020.06.09.143412 — Posted: 2020-06-11
Shielding and Beyond: The Roles of Glycans in SARS-CoV-2 Spike Protein
Casalino, L., Gaieb, Z., Dommer, A. C., Harbison, A. M., Fogarty, C. A., Barros, E. P., Taylor, B. C., Fadda, E., Amaro, R. E.
10.1101/2020.06.11.146522 — Posted: 2020-06-11
ROBOCOV: An affordable open-source robotic platform for COVID-19 testing by RT-qPCR
Villanueva-Canas, J. L., Gonzalez-Roca, E., Gastaminza Unanue, A., Titos, E., Martinez Yoldi, M. J., Vergara Gomez, A., Puig Butille, J. A.
10.1101/2020.06.11.140285 — Posted: 2020-06-11
Remdesivir but not famotidine inhibits SARS-CoV-2 replication in human pluripotent stem cell-derived intestinal organoids
Krueger, J., Gross, R., Conzelmann, C., Mueller, J. A., Koepke, L., Sparrer, K., Schuetz, D., Seufferlein, T., Barth, T. F. E., Stenger, S., Heller, S., Kleger, A., Muench, J.
10.1101/2020.06.10.144816 — Posted: 2020-06-11 Discussion: Onsite | Offsite

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).